Differentiation between Marek's disease and leukosis among laying hens, its distribution curve and preparation of vaccine against Marek's disease

Year 1977, Volume: 4 Issue: 11-12, 22 - 63, 01.12.1978

Ahmet Sipahioğlu Hamdi Girgin Aysel Ergün Reinhard Fuhr

Abstract

Ahmet Sipahioğlu; Harndi Girgin; Aysel Ergün, Reinhard
Fuht, Etlik Veteriner Kontrol ve Araştırma Enstitüsü Ankara.
This study was carried out in order to recognize the
existence of Marek's disease and leukosis, its clinical, seralogisal
and histopathological differentiation and the production
of vaccine against Marek's disease in Turkey.
Marek's disease in its acute form was observed in broilers
Only whereas laying hens showed the· chronical form of the
disease. White hens were more susceptible to the disease
whereas red . races such as Golden Commets showed the
lowest susceptibility.
1015 different organs from suspected hens were examined
histopathologically and determined 240 . of . them as Marek's
disease and 3 of the rest as lymphoid leukosis.
LL and MD were compared with relate· to cellular compositian
in these materials. LL tumors showed a uniform, large
lymphoid cells (blast cells) whereas the cells in MD were determined
· in proliferative lesions as being a.nisomorphic and
pleomorphic cells, especially various size of lymphoid cells,
reticular cells and plasma cells; it is also noticed .somotimes
heterophil granulocytes and fibrocytic cells.A vaccine against Marek's disease was -produced with
HVT - FC 126 vaccine strain. Serological rate of immunity
was 76,9 % under the laboratory conditions.
2134 sera of hens. were exkamined serologically for 1 h ··)
diagnosis of Marek's disease. İn the agar - gel precipitnti.on
tests 59,2 % of hens sefa were positive for Marek's di.sease.

Tavukların Marek ve Loukosis Hastalıklarının Araştırılması ve Marek Hastalığına Karşı Etkin bir Aşı Hazırlama

Abstract

Bu araştırma Türkiye'de MD ve LL'nin aranması, bu hastalıkların
klinik, serolojik ve histopatolijik ayırımı ve Marek
hastalığına karşı bir aşı hazırlamak için yapıldı.
Marek hastalığının akut formu sadece kasaplık piliçlerde
görüldü; buna karşın yumurtacı tavuklarda hastalığın kronik
formuna rastlanıldı. Beyaz ırkların hastalığa daha alıngan
oldukları , kırmızı ırkların örneğin Golden Commet'lerin
en düşük alınganlık gösterdikleri saptandı.
Hastalıktan şüpheli 417 hayvandan 1015 organ ve doku
parçası alındı ve bunlar histopatolojik olarak incelendi; 240
hayvanda MD, 3 hayvanda da LL bulundu-. Bu materyallerde
LL ve MD hücre kompozisyonlarına, göre karşılaştırıldı. LL
tümörlerinde bir örnek büyük lenfoid hücreler (blast hücreler),
buna karşın MD' de proliferatif lazyonlarda anizomorfik
ve pleomorfik hücreler özellikle, çeşitli büyüklükte lenfoid
hücreler, retikuler hücreler ve plasma hücreleri görüldü. MD'de
ayrıpa heterofil granulositler ve fibrositik hücreler de dikkati
çekti.Marek hastalığına karşı HVT-FC 126 aşı suşu kUllanılarak
bir aşı yapıldı. Laboratuvar koşullarında bağışıklık
oranı % 76,9 bulundu.
MD'nin serolajik teşhisi için 2134 tavuk serum u yoklan-.
dı. AGP testlerinde ·MD yönünden % 59,2 olumlu sonuç alındı.

Keywords

Marek, Tavuk, Loukosis, Marek Aşı, 1977, 1978, Ahmet SİPAHİOĞLU, Hamdi GİRGİN, Aysel ERGÜN, Reinhard FUHR

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