İnfeksiyöz Bronşitis Virusu'nun Tracheal Organ Kültürlerine Etkisi: Işık Mikroskobik İnceleme

Year 1996, Volume: 8 Issue: 4, 21 - 28, 01.12.1996

Ayşin Şen Mihriban Ülgen Deniz Mısırlıoğlu

Abstract

IBV M41 referens suşunun infektivite titrasyonu tracheal organ kültürlerinde
yapıldı ve Ml'de %50 siliostatik doz olarak ifade edildi. lB M41 suşunun titresi
Log10 5,48 CD50/ml idi. Virus-infekte tracheal halkaların histopatolojik
incelemesinde kinosilyumlarda kayıp, epitel katmanda yassılaşma ve epitel
hücrelerinde yuvarlaklaşma, piknoz ve dökülmeler gözlendi.

Keywords

IBV, tracheal organ kültürleri, histopatoloji, İnfeksiyöz Bronşitis, Ayşin ŞEN, Mihriban ÜLGEN, Deniz MISIRLIOGLU, 1996, Etlik Veteriner Mikrobiyoloji Dergisi

Effect Of Infectious Bronchitis Virus On The Tracheal Organ Cultures: Light Microscopic Examination

Abstract

Infectivity titration of IBV M4 1 strain (reference virus) were done in tracheal
organ cultures and expressed as the fıfty per cent ciliostatic dose (CD50)
per ml. The teter of the IBV M41 strain was log ı O 5,48 CD50/ml. Histopathological
examination of virus -infected tracheal rings showed loss of kynocilum,
fiattening of lamina epithelialis and pyknosis, raunding and desquamation of
epithelial cell.

Keywords

IBV, tracheal organ cultures, histopathology

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