Research Article
BibTex RIS Cite

Farelerde İvermektinle Zehirlenmelerde Sağaltım Denemeleri

Year 1996, Volume: 8 Issue: 4, 131 - 136, 01.12.1996

Abstract

Bu çalışınada 0.8-30 mg/kg arasında değişen miktarlarda farelere verilenivennektinle zehirlennıe hallarinde kafein ve neostigminin klinik olarak antidotal etkisi incelendi. Deri altı yoll<\ kafein 10 mg/kg ve neostigınin 0.025 mg/kgdozlarda uygulandı. Denemeler sonucunda kafeinin daha etkili olduğu sonucuna varıldı.

References

  • ALABAY, M. ( 1982): Veteriner hekiınlikte avennektinler ve bunların etki alanları . Vet.Hek.Dem.Derg. 42(2):37-42.
  • AMDUR,M.AAT ALL (1991): CaserettandDoull'sToxicology. 4tl'Ed. Pergaınon Press, Ine. New York, USA.
  • BENZ. G.W. AND ERNST, J.V. (1981): Anthelmintic efficacy of 22,23- dihidroavermectin B1 (I vermeeti n) against gastrointestinal nematades in calves. Amer. J.VetRes. 42:1409-1411.
  • CAMPBELL, W. C. AND BLAIR, LS. ( 1978): Efficacy of avennectins against Drofilaria immilis in dog. J.Helminthol. 52:308-310.
  • EAGLESON, J.S. AND ALLERTON, G.R. (1992): Efficacy and safety of iverınectin applied topically to cattle under field conditions in Australia. Aust. Vet. 69(6): 133-134.
  • EGERTON, J.R., AT ALL (1979): Avennectins, newfamily ofpotent anthelmin tic agents: efficacy oftheB1, component. Antimicrob. Agents. Chemother. 15 :372-378.
  • GOODMAN, G. AT ALL (1991): Goodman and Gilman's The Phannacological Basis ofTherapeutics 8tl'Ed. Pergamon Press, Ine/New York, USA.
  • Kll.,GORE, R.L. AT ALL (1983): Response of horses to repeated intraınuscular injections ofivennectin. Vet.Med.Sınall.Aniın. C lin. 78: 1894-1897.
  • KURTDEDE, A. VE ARK. (1992) : Köpeklerde deneysel iverınektin toksikasyonunda picrotoxin kullarunu. Ankara Üniv. Vet.Fak.Derg. 39(1-2):20 1-206.
  • KURTDEDE, A VE ARK. (1 990): Köpeklerde deneysel ivennektin toksikasyonu. Ankara Üniv.\et.Fak.Derg. 37(3):5:9-608.
  • LYONS, E. T. AT ALL (1980): Antiparasi tic activity ofivennectin in critical tesıs inequids. Aıner. J.Vet.Res. 41 :2069-2072.
  • MAN GER, B.R ( 1992): Antlıelmintics 413-548. Veterinary Applied Phannacology and Therapeutics. Fifth Edition In: G.C. Brander, D.M.Pugh, R.J.Bywater and W.L.Jenkins (Eds). Bailliere Tindall, London.
  • MELLIN, T.N. AT ALL (1983): Postsynaptic inhibition ofinvertebrate neuromuscular transmission by avermectin B,._ Neuropharmacology. 22:89-96.
  • OSTLIND, D.A. AT All (1979): Insecticidal activity of the antiparasİtic avermectins. Vet.Rec. 105 :168.
  • . PLUMB, D. C. (1991): Veterinary Drug Handbook. Pocket Edition. Pharma Vet Publishing, USA. PONG, S.S. AND WANG, C.C (1982): AvennectinB,.ınodulationofgaınınaaminobutyric acid receptors in rat brain membranes. J.Neurochem. 38:375-379.
  • ROBERSON, E.L. (1988): Chemotherapy of parasitic diseases: Introduction and antinematodal drugs. 877-92 7. In :M. H.Bootlı and L.E.Mc Donald(Eds): In: Veterinary Phannacology and Therapeutics. 6th Edi tion. Iowa State Universty Press, Ames, Iowa.
  • SEWARD, RL. (1983): Reactions in doggiven ivennectin. J.Amer. Vet. Med. Assoc. 183:493.
  • KAYA, S. (1994). Spesiyalitelerin kısa taıuını . 41-356. İçinde:Y. Şanlı ve S.Kaya (1994). Veteriner İlaç Rehberi ve Uygulaınalı Bilgiler El Kitabı. Medisan Yayı nevi, Yayın No 15, Ankara

Therapeutic Applications In Ivermect In Poisoning Mice

Year 1996, Volume: 8 Issue: 4, 131 - 136, 01.12.1996

Abstract

In this study, antidotal effects of caffeine and neostigmine were investigated clinically in mice poisoned with ivermectin usedin doses of0.8 to 30 mg/kg body weight. Caffeine and neostigmine were given subcutaneously at dose level of 10 mg/kg and neostigmine 0.025 mg/kg body weight respectively. It was concluded from the experiments that caffeine was more effective than neostigmine

References

  • ALABAY, M. ( 1982): Veteriner hekiınlikte avennektinler ve bunların etki alanları . Vet.Hek.Dem.Derg. 42(2):37-42.
  • AMDUR,M.AAT ALL (1991): CaserettandDoull'sToxicology. 4tl'Ed. Pergaınon Press, Ine. New York, USA.
  • BENZ. G.W. AND ERNST, J.V. (1981): Anthelmintic efficacy of 22,23- dihidroavermectin B1 (I vermeeti n) against gastrointestinal nematades in calves. Amer. J.VetRes. 42:1409-1411.
  • CAMPBELL, W. C. AND BLAIR, LS. ( 1978): Efficacy of avennectins against Drofilaria immilis in dog. J.Helminthol. 52:308-310.
  • EAGLESON, J.S. AND ALLERTON, G.R. (1992): Efficacy and safety of iverınectin applied topically to cattle under field conditions in Australia. Aust. Vet. 69(6): 133-134.
  • EGERTON, J.R., AT ALL (1979): Avennectins, newfamily ofpotent anthelmin tic agents: efficacy oftheB1, component. Antimicrob. Agents. Chemother. 15 :372-378.
  • GOODMAN, G. AT ALL (1991): Goodman and Gilman's The Phannacological Basis ofTherapeutics 8tl'Ed. Pergamon Press, Ine/New York, USA.
  • Kll.,GORE, R.L. AT ALL (1983): Response of horses to repeated intraınuscular injections ofivennectin. Vet.Med.Sınall.Aniın. C lin. 78: 1894-1897.
  • KURTDEDE, A. VE ARK. (1992) : Köpeklerde deneysel iverınektin toksikasyonunda picrotoxin kullarunu. Ankara Üniv. Vet.Fak.Derg. 39(1-2):20 1-206.
  • KURTDEDE, A VE ARK. (1 990): Köpeklerde deneysel ivennektin toksikasyonu. Ankara Üniv.\et.Fak.Derg. 37(3):5:9-608.
  • LYONS, E. T. AT ALL (1980): Antiparasi tic activity ofivennectin in critical tesıs inequids. Aıner. J.Vet.Res. 41 :2069-2072.
  • MAN GER, B.R ( 1992): Antlıelmintics 413-548. Veterinary Applied Phannacology and Therapeutics. Fifth Edition In: G.C. Brander, D.M.Pugh, R.J.Bywater and W.L.Jenkins (Eds). Bailliere Tindall, London.
  • MELLIN, T.N. AT ALL (1983): Postsynaptic inhibition ofinvertebrate neuromuscular transmission by avermectin B,._ Neuropharmacology. 22:89-96.
  • OSTLIND, D.A. AT All (1979): Insecticidal activity of the antiparasİtic avermectins. Vet.Rec. 105 :168.
  • . PLUMB, D. C. (1991): Veterinary Drug Handbook. Pocket Edition. Pharma Vet Publishing, USA. PONG, S.S. AND WANG, C.C (1982): AvennectinB,.ınodulationofgaınınaaminobutyric acid receptors in rat brain membranes. J.Neurochem. 38:375-379.
  • ROBERSON, E.L. (1988): Chemotherapy of parasitic diseases: Introduction and antinematodal drugs. 877-92 7. In :M. H.Bootlı and L.E.Mc Donald(Eds): In: Veterinary Phannacology and Therapeutics. 6th Edi tion. Iowa State Universty Press, Ames, Iowa.
  • SEWARD, RL. (1983): Reactions in doggiven ivennectin. J.Amer. Vet. Med. Assoc. 183:493.
  • KAYA, S. (1994). Spesiyalitelerin kısa taıuını . 41-356. İçinde:Y. Şanlı ve S.Kaya (1994). Veteriner İlaç Rehberi ve Uygulaınalı Bilgiler El Kitabı. Medisan Yayı nevi, Yayın No 15, Ankara
There are 18 citations in total.

Details

Primary Language Turkish
Subjects Veterinary Surgery
Journal Section Original Article
Authors

Ali Bilgili This is me

Sezai Kaya This is me

Ender Yarsan This is me

Publication Date December 1, 1996
Submission Date December 1, 1996
Published in Issue Year 1996 Volume: 8 Issue: 4

Cite

APA Bilgili, A., Kaya, S., & Yarsan, E. (1996). Farelerde İvermektinle Zehirlenmelerde Sağaltım Denemeleri. Etlik Veteriner Mikrobiyoloji Dergisi, 8(4), 131-136.

download