Araştırma Makalesi
BibTex RIS Kaynak Göster

Farelerde İvermektinle Zehirlenmelerde Sağaltım Denemeleri

Yıl 1996, Cilt: 8 Sayı: 4, 131 - 136, 01.12.1996

Öz

Bu çalışınada 0.8-30 mg/kg arasında değişen miktarlarda farelere verilenivennektinle zehirlennıe hallarinde kafein ve neostigminin klinik olarak antidotal etkisi incelendi. Deri altı yoll<\ kafein 10 mg/kg ve neostigınin 0.025 mg/kgdozlarda uygulandı. Denemeler sonucunda kafeinin daha etkili olduğu sonucuna varıldı.

Kaynakça

  • ALABAY, M. ( 1982): Veteriner hekiınlikte avennektinler ve bunların etki alanları . Vet.Hek.Dem.Derg. 42(2):37-42.
  • AMDUR,M.AAT ALL (1991): CaserettandDoull'sToxicology. 4tl'Ed. Pergaınon Press, Ine. New York, USA.
  • BENZ. G.W. AND ERNST, J.V. (1981): Anthelmintic efficacy of 22,23- dihidroavermectin B1 (I vermeeti n) against gastrointestinal nematades in calves. Amer. J.VetRes. 42:1409-1411.
  • CAMPBELL, W. C. AND BLAIR, LS. ( 1978): Efficacy of avennectins against Drofilaria immilis in dog. J.Helminthol. 52:308-310.
  • EAGLESON, J.S. AND ALLERTON, G.R. (1992): Efficacy and safety of iverınectin applied topically to cattle under field conditions in Australia. Aust. Vet. 69(6): 133-134.
  • EGERTON, J.R., AT ALL (1979): Avennectins, newfamily ofpotent anthelmin tic agents: efficacy oftheB1, component. Antimicrob. Agents. Chemother. 15 :372-378.
  • GOODMAN, G. AT ALL (1991): Goodman and Gilman's The Phannacological Basis ofTherapeutics 8tl'Ed. Pergamon Press, Ine/New York, USA.
  • Kll.,GORE, R.L. AT ALL (1983): Response of horses to repeated intraınuscular injections ofivennectin. Vet.Med.Sınall.Aniın. C lin. 78: 1894-1897.
  • KURTDEDE, A. VE ARK. (1992) : Köpeklerde deneysel iverınektin toksikasyonunda picrotoxin kullarunu. Ankara Üniv. Vet.Fak.Derg. 39(1-2):20 1-206.
  • KURTDEDE, A VE ARK. (1 990): Köpeklerde deneysel ivennektin toksikasyonu. Ankara Üniv.\et.Fak.Derg. 37(3):5:9-608.
  • LYONS, E. T. AT ALL (1980): Antiparasi tic activity ofivennectin in critical tesıs inequids. Aıner. J.Vet.Res. 41 :2069-2072.
  • MAN GER, B.R ( 1992): Antlıelmintics 413-548. Veterinary Applied Phannacology and Therapeutics. Fifth Edition In: G.C. Brander, D.M.Pugh, R.J.Bywater and W.L.Jenkins (Eds). Bailliere Tindall, London.
  • MELLIN, T.N. AT ALL (1983): Postsynaptic inhibition ofinvertebrate neuromuscular transmission by avermectin B,._ Neuropharmacology. 22:89-96.
  • OSTLIND, D.A. AT All (1979): Insecticidal activity of the antiparasİtic avermectins. Vet.Rec. 105 :168.
  • . PLUMB, D. C. (1991): Veterinary Drug Handbook. Pocket Edition. Pharma Vet Publishing, USA. PONG, S.S. AND WANG, C.C (1982): AvennectinB,.ınodulationofgaınınaaminobutyric acid receptors in rat brain membranes. J.Neurochem. 38:375-379.
  • ROBERSON, E.L. (1988): Chemotherapy of parasitic diseases: Introduction and antinematodal drugs. 877-92 7. In :M. H.Bootlı and L.E.Mc Donald(Eds): In: Veterinary Phannacology and Therapeutics. 6th Edi tion. Iowa State Universty Press, Ames, Iowa.
  • SEWARD, RL. (1983): Reactions in doggiven ivennectin. J.Amer. Vet. Med. Assoc. 183:493.
  • KAYA, S. (1994). Spesiyalitelerin kısa taıuını . 41-356. İçinde:Y. Şanlı ve S.Kaya (1994). Veteriner İlaç Rehberi ve Uygulaınalı Bilgiler El Kitabı. Medisan Yayı nevi, Yayın No 15, Ankara

Therapeutic Applications In Ivermect In Poisoning Mice

Yıl 1996, Cilt: 8 Sayı: 4, 131 - 136, 01.12.1996

Öz

In this study, antidotal effects of caffeine and neostigmine were investigated clinically in mice poisoned with ivermectin usedin doses of0.8 to 30 mg/kg body weight. Caffeine and neostigmine were given subcutaneously at dose level of 10 mg/kg and neostigmine 0.025 mg/kg body weight respectively. It was concluded from the experiments that caffeine was more effective than neostigmine

Kaynakça

  • ALABAY, M. ( 1982): Veteriner hekiınlikte avennektinler ve bunların etki alanları . Vet.Hek.Dem.Derg. 42(2):37-42.
  • AMDUR,M.AAT ALL (1991): CaserettandDoull'sToxicology. 4tl'Ed. Pergaınon Press, Ine. New York, USA.
  • BENZ. G.W. AND ERNST, J.V. (1981): Anthelmintic efficacy of 22,23- dihidroavermectin B1 (I vermeeti n) against gastrointestinal nematades in calves. Amer. J.VetRes. 42:1409-1411.
  • CAMPBELL, W. C. AND BLAIR, LS. ( 1978): Efficacy of avennectins against Drofilaria immilis in dog. J.Helminthol. 52:308-310.
  • EAGLESON, J.S. AND ALLERTON, G.R. (1992): Efficacy and safety of iverınectin applied topically to cattle under field conditions in Australia. Aust. Vet. 69(6): 133-134.
  • EGERTON, J.R., AT ALL (1979): Avennectins, newfamily ofpotent anthelmin tic agents: efficacy oftheB1, component. Antimicrob. Agents. Chemother. 15 :372-378.
  • GOODMAN, G. AT ALL (1991): Goodman and Gilman's The Phannacological Basis ofTherapeutics 8tl'Ed. Pergamon Press, Ine/New York, USA.
  • Kll.,GORE, R.L. AT ALL (1983): Response of horses to repeated intraınuscular injections ofivennectin. Vet.Med.Sınall.Aniın. C lin. 78: 1894-1897.
  • KURTDEDE, A. VE ARK. (1992) : Köpeklerde deneysel iverınektin toksikasyonunda picrotoxin kullarunu. Ankara Üniv. Vet.Fak.Derg. 39(1-2):20 1-206.
  • KURTDEDE, A VE ARK. (1 990): Köpeklerde deneysel ivennektin toksikasyonu. Ankara Üniv.\et.Fak.Derg. 37(3):5:9-608.
  • LYONS, E. T. AT ALL (1980): Antiparasi tic activity ofivennectin in critical tesıs inequids. Aıner. J.Vet.Res. 41 :2069-2072.
  • MAN GER, B.R ( 1992): Antlıelmintics 413-548. Veterinary Applied Phannacology and Therapeutics. Fifth Edition In: G.C. Brander, D.M.Pugh, R.J.Bywater and W.L.Jenkins (Eds). Bailliere Tindall, London.
  • MELLIN, T.N. AT ALL (1983): Postsynaptic inhibition ofinvertebrate neuromuscular transmission by avermectin B,._ Neuropharmacology. 22:89-96.
  • OSTLIND, D.A. AT All (1979): Insecticidal activity of the antiparasİtic avermectins. Vet.Rec. 105 :168.
  • . PLUMB, D. C. (1991): Veterinary Drug Handbook. Pocket Edition. Pharma Vet Publishing, USA. PONG, S.S. AND WANG, C.C (1982): AvennectinB,.ınodulationofgaınınaaminobutyric acid receptors in rat brain membranes. J.Neurochem. 38:375-379.
  • ROBERSON, E.L. (1988): Chemotherapy of parasitic diseases: Introduction and antinematodal drugs. 877-92 7. In :M. H.Bootlı and L.E.Mc Donald(Eds): In: Veterinary Phannacology and Therapeutics. 6th Edi tion. Iowa State Universty Press, Ames, Iowa.
  • SEWARD, RL. (1983): Reactions in doggiven ivennectin. J.Amer. Vet. Med. Assoc. 183:493.
  • KAYA, S. (1994). Spesiyalitelerin kısa taıuını . 41-356. İçinde:Y. Şanlı ve S.Kaya (1994). Veteriner İlaç Rehberi ve Uygulaınalı Bilgiler El Kitabı. Medisan Yayı nevi, Yayın No 15, Ankara
Toplam 18 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Veteriner Cerrahi
Bölüm Araştırma Makaleleri
Yazarlar

Ali Bilgili Bu kişi benim

Sezai Kaya Bu kişi benim

Ender Yarsan Bu kişi benim

Yayımlanma Tarihi 1 Aralık 1996
Gönderilme Tarihi 1 Aralık 1996
Yayımlandığı Sayı Yıl 1996 Cilt: 8 Sayı: 4

Kaynak Göster

APA Bilgili, A., Kaya, S., & Yarsan, E. (1996). Farelerde İvermektinle Zehirlenmelerde Sağaltım Denemeleri. Etlik Veteriner Mikrobiyoloji Dergisi, 8(4), 131-136.


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