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21. Yüzyıl Kimya Laboratuvarında Güvenlik Paradigması: Proaktif Stratejiler, Dijital Dönüşüm ve İnsan Odaklı Yaklaşımlar

Year 2025, Volume: 14 Issue: 2, 16 - 33, 30.11.2025

Abstract

Bu derleme, 21. yüzyıl kimya laboratuvarlarında iş sağlığı ve güvenliği (İSG) alanındaki paradigma değişimini ele almaktadır. Geleneksel reaktif yaklaşımların yerini alan proaktif stratejiler, dijital dönüşümün getirdiği yenilikler ve insan odaklı güvenlik kültürü uygulamaları merkeze alınmıştır. Makale, nanomalzemeler gibi yeni nesil tehlikelerden başlayarak, risk yönetimindeki evrimi, otomasyon ve akıllı laboratuvar teknolojilerini, giyilebilir sensörleri, yapay zeka destekli öngörücü güvenlik sistemlerini ve sanal/artırılmış gerçeklik tabanlı eğitimleri detaylı bir şekilde incelemektedir. Özellikle kimya öğrencilerinin ve genç araştırmacıların İSG bilincinin artırılması, müfredat entegrasyonu, insan faktörleri ve davranışsal güvenlik konuları vurgulanmaktadır. İSG'nin yeşil kimya ve sürdürülebilirlik prensipleriyle kesişimi, gelecekteki araştırma yönelimleri, teknolojik atılımlar ve politika önerileri de sunulmaktadır. Derleme, geleceğin kimyagerlerine güvenlik elçileri ve değişim liderleri olmaları yönünde bir çağrı yaparak, İSG alanındaki potansiyel kariyer fırsatlarına dikkat çekmektedir. Temel argüman, güçlü bir İSG çerçevesinin bilimsel inovasyonun temel bir katalizörü olduğu ve en güvenli laboratuvarın bilinçli, sorgulayan ve güvenliği bir yaşam biçimi olarak benimsemiş bireylerle mümkün olacağıdır.

References

  • Adadi, A., & Berrada, M. (2018). Peeking Inside the Black-Box: A Survey on Explainable Artificial Intelligence (XAI). IEEE Access, 6, 52138-52160. https://doi.org/10.1109/ACCESS.2018.2870079
  • Ahamad, M. R., Kushwaha, K. P. S., & Kundu, S. (2022). Systematic Literature Review on Variables Impacting Organization’s Zero Accident Vision (ZAV) Implementation. Sustainability, 14(13), 7523. MDPI. https://www.mdpi.com/2071-1050/14/13/7523
  • American Chemical Society, Committee on Chemical Safety. (2023). Safety in Academic Chemistry Laboratories (9th ed.). ACS. https://www.acs.org
  • Anastas, P. T., & Warner, J. C. (1998). Green Chemistry: Theory and Practice. Oxford University Press.
  • Bogue, R. (2012). Robots in the laboratory: a review of applications. Industrial Robot, 39(2), 113-119. https://doi.org/10.1108/01439911211203382
  • Burange, A. S., Osman, S. M., & Luque, R. (2023). The future of MXenes. Chemistry of Materials, 35(35), 8767-8770. https://doi.org/10.1021/acs.chemmater.3c02491
  • Chemical Safety Board (CSB). (2011). Texas Tech University Chemistry Lab Explosion (Case Study No. 2010-05-I-TX). U.S. Chemical Safety and Hazard Investigation Board. https://www.csb.gov/
  • Cooper, M. D. (2000). Towards a model of safety culture. Safety Science, 36(2), 111-136. https://doi.org/10.1016/S0925-7535(00)00035-7
  • Deng, S., Li, C., Cao, J., Cui, Z., Du, J., Fu, Z., Yang, H., & Chen, P. (2023). Organ-on-a-chip meets artificial intelligence in drug evaluation. Theranostics, 13(13), 4526-4558. https://doi.org/10.7150/thno.87266
  • ECHA (European Chemicals Agency). (2023). Guidance on Information Requirements and Chemical Safety Assessment - Chapter R.7a: Endpoint specific guidance (Version 7.0). European Chemicals Agency.
  • European Agency for Safety and Health at Work. (2023, July 25). The role of Vision Zero and related occupational safety & health strategies, interventions, and tools in reducing EU work related fatalities, accidents and ill health. OSHwiki. https://oshwiki.osha.europa.eu/en/themes/role-vision-zero-and-related-occupational-safety-health-strategies-interventions-and-tools
  • Flin, R., Mearns, K., O'Connor, P., & Bryden, R. (2000). Measuring safety climate: identifying the common features. Safety Science, 34(1-3), 177-192. https://doi.org/10.1016/S0925-7535(00)00037-3
  • Guthrie, S., Lichten, C. A., van Belle, J., Ball, S., Knack, A., & Hofman, J. (2018). Understanding mental health in the research environment: A Rapid Evidence Assessment. RAND Corporation. https://doi.org/10.7249/RR2022
  • Hou, W., Zhang, Y., Huang, F., Xu, H., et al. (2024). Nanomole-scale medical chemistry and bioconjugation-compatible bioinspired selenium–nitrogen exchange (SeNEx) click chemistry. Angewandte Chemie, 136(15). https://doi.org/10.1002/ange.202318534
  • Ismael, M., McCall, R., McGee, F., Belkacem, I., Stefas, M., Baixauli, J., & Arl, D. (2024). Acceptance of augmented reality in laboratory safety training: Methodology and an evaluation study. Frontiers in Virtual Reality, 5. https://doi.org/10.3389/frvir.2024.1322543
  • Jin, X., Zhang, H., & Wang, X. (2025). Kimyasal İlgili Akademik Laboratuvarların Emniyet ve Güvenlik Risk Yönetimindeki Önyargılar. Laboratories, 2(2), 11. https://doi.org/10.3390/laboratories2020011
  • Kemsley, J. (2015). Learning from UCLA. Chemical & Engineering News, 93(6), 29-34. https://doi.org/10.1021/cen-09306-cover
  • Kümmerer, K., & Clark, J. H. (2020). Sustainability and circular economy in the chemistry curriculum. Green Chemistry, 22(18), 5917-5920. https://doi.org/10.1126/science.aba4979
  • Lee, S., Kim, J., Kim, D., Lee, G., et al. (2024). Wearable volatile organic compound sensors for plant health monitoring. Advanced Sustainable Systems.
  • Maheronnaghsh, S., Zolfagharnasab, H., Gorgich, M., & Duarte, J. (2023). Machine learning in occupational safety and health: A systematic review. International Journal of Occupational and Environmental Safety, 7(1), 14-32. https://doi.org/10.24840/2184-0954_007-001_001586
  • Mittelstadt, B. D., Allo, P., Taddeo, M., Wachter, S., & Floridi, L. (2016). The ethics of algorithms: Mapping the debate. Big Data & Society, 3(2), 2053951716679679. https://doi.org/10.1177/2053951716666516
  • Mould, R. F. (1993). A century of X-rays and radioactivity in medicine: With emphasis on photographic records of the early years (1st ed.). CRC Press. https://doi.org/10.1201/9781315136271
  • Mughal, B. (2023, October 1). Zero Accidents: 10 Steps To Achieve This Goal At Workplace. HSE Blog. https://www.hseblog.com/zero-accidents/
  • National Research Council, Committee on Prudent Practices in the Laboratory. (2014). Safe science: Promoting a culture of safety in academic chemical research. The National Academies Press. https://doi.org/10.17226/18874
  • Nyström, A. M., & Fadeel, B. (2012). Safety assessment of nanomaterials: Implications for nanomedicine. Journal of Controlled Release, 161(2), 403-408. https://doi.org/10.1016/j.jconrel.2012.01.027
  • Reason, J. (2000). Human error: models and management. BMJ, 320(7237), 768-770. https://doi.org/10.1136/bmj.320.7237.768
  • Safety Partners, Inc. (2025). Incidents, Accidents, and Near Misses in Laboratory Research (Vol. 9). Safety Partners, Inc. https://www.safetypartnersinc.com/wp-content/uploads/2025/01/IANM_Publication_Vol_9_DIGITAL.pdf
  • Wang, W., Su, Y., Cao, H., & Li, D. (2025). Enhancing Chemical Laboratory Safety with Hazards Risks Mitigation and Strategic Actions. Laboratories, 2(1), 5. https://doi.org/10.3390/laboratories2010005
  • Zwetsloot, G., Kines, P., Ruotsala, R., Drupsteen, L., & Bezemer, R. (2017). Zero Accident Vision based strategies in organisations: Innovative perspectives. NIVA. https://niva.org/app/uploads/Zwetsloot_Kines-et-al-Vision-Zero-Perspectives-SafSci2017.pdf

Safety Paradigm in 21st Century Chemistry Laboratories: Proactive Strategies, Digital Transformation, and Human-Centered Approaches

Year 2025, Volume: 14 Issue: 2, 16 - 33, 30.11.2025

Abstract

This review addresses the paradigm shift in occupational health and safety (OHS) in 21st-century chemistry laboratories. Proactive strategies, innovations brought by digital transformation, and human-centered safety culture practices have replaced traditional reactive approaches. The article provides a detailed examination of the evolution of risk management, automation, innovative laboratory technologies, wearable sensors, AI-supported predictive safety systems, and virtual/augmented reality-based training, starting with new-generation hazards such as nanomaterials. Particular emphasis is placed on raising OSH awareness among chemistry students and young researchers, curriculum integration, human factors, and behavioral safety issues. The intersection of OSH with green chemistry and sustainability principles, future research directions, technological advances, and policy recommendations is also presented. The review calls on future chemists to become safety ambassadors and change leaders, highlighting potential career opportunities in the field of OSH. The central argument is that a strong OSH framework is a fundamental catalyst for scientific innovation. The safest laboratory is one where individuals are conscious, inquisitive, and have adopted safety as a way of life.

References

  • Adadi, A., & Berrada, M. (2018). Peeking Inside the Black-Box: A Survey on Explainable Artificial Intelligence (XAI). IEEE Access, 6, 52138-52160. https://doi.org/10.1109/ACCESS.2018.2870079
  • Ahamad, M. R., Kushwaha, K. P. S., & Kundu, S. (2022). Systematic Literature Review on Variables Impacting Organization’s Zero Accident Vision (ZAV) Implementation. Sustainability, 14(13), 7523. MDPI. https://www.mdpi.com/2071-1050/14/13/7523
  • American Chemical Society, Committee on Chemical Safety. (2023). Safety in Academic Chemistry Laboratories (9th ed.). ACS. https://www.acs.org
  • Anastas, P. T., & Warner, J. C. (1998). Green Chemistry: Theory and Practice. Oxford University Press.
  • Bogue, R. (2012). Robots in the laboratory: a review of applications. Industrial Robot, 39(2), 113-119. https://doi.org/10.1108/01439911211203382
  • Burange, A. S., Osman, S. M., & Luque, R. (2023). The future of MXenes. Chemistry of Materials, 35(35), 8767-8770. https://doi.org/10.1021/acs.chemmater.3c02491
  • Chemical Safety Board (CSB). (2011). Texas Tech University Chemistry Lab Explosion (Case Study No. 2010-05-I-TX). U.S. Chemical Safety and Hazard Investigation Board. https://www.csb.gov/
  • Cooper, M. D. (2000). Towards a model of safety culture. Safety Science, 36(2), 111-136. https://doi.org/10.1016/S0925-7535(00)00035-7
  • Deng, S., Li, C., Cao, J., Cui, Z., Du, J., Fu, Z., Yang, H., & Chen, P. (2023). Organ-on-a-chip meets artificial intelligence in drug evaluation. Theranostics, 13(13), 4526-4558. https://doi.org/10.7150/thno.87266
  • ECHA (European Chemicals Agency). (2023). Guidance on Information Requirements and Chemical Safety Assessment - Chapter R.7a: Endpoint specific guidance (Version 7.0). European Chemicals Agency.
  • European Agency for Safety and Health at Work. (2023, July 25). The role of Vision Zero and related occupational safety & health strategies, interventions, and tools in reducing EU work related fatalities, accidents and ill health. OSHwiki. https://oshwiki.osha.europa.eu/en/themes/role-vision-zero-and-related-occupational-safety-health-strategies-interventions-and-tools
  • Flin, R., Mearns, K., O'Connor, P., & Bryden, R. (2000). Measuring safety climate: identifying the common features. Safety Science, 34(1-3), 177-192. https://doi.org/10.1016/S0925-7535(00)00037-3
  • Guthrie, S., Lichten, C. A., van Belle, J., Ball, S., Knack, A., & Hofman, J. (2018). Understanding mental health in the research environment: A Rapid Evidence Assessment. RAND Corporation. https://doi.org/10.7249/RR2022
  • Hou, W., Zhang, Y., Huang, F., Xu, H., et al. (2024). Nanomole-scale medical chemistry and bioconjugation-compatible bioinspired selenium–nitrogen exchange (SeNEx) click chemistry. Angewandte Chemie, 136(15). https://doi.org/10.1002/ange.202318534
  • Ismael, M., McCall, R., McGee, F., Belkacem, I., Stefas, M., Baixauli, J., & Arl, D. (2024). Acceptance of augmented reality in laboratory safety training: Methodology and an evaluation study. Frontiers in Virtual Reality, 5. https://doi.org/10.3389/frvir.2024.1322543
  • Jin, X., Zhang, H., & Wang, X. (2025). Kimyasal İlgili Akademik Laboratuvarların Emniyet ve Güvenlik Risk Yönetimindeki Önyargılar. Laboratories, 2(2), 11. https://doi.org/10.3390/laboratories2020011
  • Kemsley, J. (2015). Learning from UCLA. Chemical & Engineering News, 93(6), 29-34. https://doi.org/10.1021/cen-09306-cover
  • Kümmerer, K., & Clark, J. H. (2020). Sustainability and circular economy in the chemistry curriculum. Green Chemistry, 22(18), 5917-5920. https://doi.org/10.1126/science.aba4979
  • Lee, S., Kim, J., Kim, D., Lee, G., et al. (2024). Wearable volatile organic compound sensors for plant health monitoring. Advanced Sustainable Systems.
  • Maheronnaghsh, S., Zolfagharnasab, H., Gorgich, M., & Duarte, J. (2023). Machine learning in occupational safety and health: A systematic review. International Journal of Occupational and Environmental Safety, 7(1), 14-32. https://doi.org/10.24840/2184-0954_007-001_001586
  • Mittelstadt, B. D., Allo, P., Taddeo, M., Wachter, S., & Floridi, L. (2016). The ethics of algorithms: Mapping the debate. Big Data & Society, 3(2), 2053951716679679. https://doi.org/10.1177/2053951716666516
  • Mould, R. F. (1993). A century of X-rays and radioactivity in medicine: With emphasis on photographic records of the early years (1st ed.). CRC Press. https://doi.org/10.1201/9781315136271
  • Mughal, B. (2023, October 1). Zero Accidents: 10 Steps To Achieve This Goal At Workplace. HSE Blog. https://www.hseblog.com/zero-accidents/
  • National Research Council, Committee on Prudent Practices in the Laboratory. (2014). Safe science: Promoting a culture of safety in academic chemical research. The National Academies Press. https://doi.org/10.17226/18874
  • Nyström, A. M., & Fadeel, B. (2012). Safety assessment of nanomaterials: Implications for nanomedicine. Journal of Controlled Release, 161(2), 403-408. https://doi.org/10.1016/j.jconrel.2012.01.027
  • Reason, J. (2000). Human error: models and management. BMJ, 320(7237), 768-770. https://doi.org/10.1136/bmj.320.7237.768
  • Safety Partners, Inc. (2025). Incidents, Accidents, and Near Misses in Laboratory Research (Vol. 9). Safety Partners, Inc. https://www.safetypartnersinc.com/wp-content/uploads/2025/01/IANM_Publication_Vol_9_DIGITAL.pdf
  • Wang, W., Su, Y., Cao, H., & Li, D. (2025). Enhancing Chemical Laboratory Safety with Hazards Risks Mitigation and Strategic Actions. Laboratories, 2(1), 5. https://doi.org/10.3390/laboratories2010005
  • Zwetsloot, G., Kines, P., Ruotsala, R., Drupsteen, L., & Bezemer, R. (2017). Zero Accident Vision based strategies in organisations: Innovative perspectives. NIVA. https://niva.org/app/uploads/Zwetsloot_Kines-et-al-Vision-Zero-Perspectives-SafSci2017.pdf
There are 29 citations in total.

Details

Primary Language Turkish
Subjects Physical Chemistry (Other)
Journal Section Review
Authors

Yakup Budak 0000-0001-7108-5548

Meliha Burcu Gürdere

Mustafa Ceylan 0000-0002-9184-4385

Early Pub Date November 26, 2025
Publication Date November 30, 2025
Submission Date May 15, 2025
Acceptance Date November 4, 2025
Published in Issue Year 2025 Volume: 14 Issue: 2

Cite

APA Budak, Y., Gürdere, M. B., & Ceylan, M. (2025). 21. Yüzyıl Kimya Laboratuvarında Güvenlik Paradigması: Proaktif Stratejiler, Dijital Dönüşüm ve İnsan Odaklı Yaklaşımlar. Gaziosmanpaşa Bilimsel Araştırma Dergisi, 14(2), 16-33.
AMA Budak Y, Gürdere MB, Ceylan M. 21. Yüzyıl Kimya Laboratuvarında Güvenlik Paradigması: Proaktif Stratejiler, Dijital Dönüşüm ve İnsan Odaklı Yaklaşımlar. GBAD. November 2025;14(2):16-33.
Chicago Budak, Yakup, Meliha Burcu Gürdere, and Mustafa Ceylan. “21. Yüzyıl Kimya Laboratuvarında Güvenlik Paradigması: Proaktif Stratejiler, Dijital Dönüşüm Ve İnsan Odaklı Yaklaşımlar”. Gaziosmanpaşa Bilimsel Araştırma Dergisi 14, no. 2 (November 2025): 16-33.
EndNote Budak Y, Gürdere MB, Ceylan M (November 1, 2025) 21. Yüzyıl Kimya Laboratuvarında Güvenlik Paradigması: Proaktif Stratejiler, Dijital Dönüşüm ve İnsan Odaklı Yaklaşımlar. Gaziosmanpaşa Bilimsel Araştırma Dergisi 14 2 16–33.
IEEE Y. Budak, M. B. Gürdere, and M. Ceylan, “21. Yüzyıl Kimya Laboratuvarında Güvenlik Paradigması: Proaktif Stratejiler, Dijital Dönüşüm ve İnsan Odaklı Yaklaşımlar”, GBAD, vol. 14, no. 2, pp. 16–33, 2025.
ISNAD Budak, Yakup et al. “21. Yüzyıl Kimya Laboratuvarında Güvenlik Paradigması: Proaktif Stratejiler, Dijital Dönüşüm Ve İnsan Odaklı Yaklaşımlar”. Gaziosmanpaşa Bilimsel Araştırma Dergisi 14/2 (November2025), 16-33.
JAMA Budak Y, Gürdere MB, Ceylan M. 21. Yüzyıl Kimya Laboratuvarında Güvenlik Paradigması: Proaktif Stratejiler, Dijital Dönüşüm ve İnsan Odaklı Yaklaşımlar. GBAD. 2025;14:16–33.
MLA Budak, Yakup et al. “21. Yüzyıl Kimya Laboratuvarında Güvenlik Paradigması: Proaktif Stratejiler, Dijital Dönüşüm Ve İnsan Odaklı Yaklaşımlar”. Gaziosmanpaşa Bilimsel Araştırma Dergisi, vol. 14, no. 2, 2025, pp. 16-33.
Vancouver Budak Y, Gürdere MB, Ceylan M. 21. Yüzyıl Kimya Laboratuvarında Güvenlik Paradigması: Proaktif Stratejiler, Dijital Dönüşüm ve İnsan Odaklı Yaklaşımlar. GBAD. 2025;14(2):16-33.