The Effect of Treatment for Attention-Deficit/ Hyperactivity Disorder on Children's Symptoms and Caregivers' Quality of Life: A Prospective Study
Abstract
Aim: Attention-Deficit/Hyperactivity Disorder (ADHD) affects not only children’s mental health but also their parents’ psychological well-being. This study examined the impact of ADHD treatment on children’s symptoms and the quality of life (QoL) of their caregivers.
Materials and Methods: The study involved 100 children aged 6 to 17 who were newly diagnosed with ADHD and starting treatment, along with their 100 primary caregivers. Children were evaluated using
the Conners’ Parent Rating Scale–Revised: Long Form (CPRS-RL), while caregivers were assessed with the Short-Form 36 (SF-36) Scale, Hamilton Anxiety (HAM-A), and Depression (HAM-D) Scales. Mental status examinations and assessments were conducted at treatment initiation and repeated after three months.
Results: A statistically significant reduction was observed in CPRS-RL scores after three months of treatment (z = -8.385, p < 0.001). No significant difference was found in symptom reduction between those receiving stimulant versus non-stimulant medications (p = 0.541). Caregivers showed statistically significant improvements in all SF-36 subdomains after three months (p <0.001). When SF-36 score changes were compared according to the ADHD subtype of the children, significant differences remained between the inattentive and hyperactive (p < 0.001), and inattentive and combined type groups (p < 0.017), while no significant difference was observed between the hyperactive and combined type groups (p > 0.017). No significant changes were found in caregivers’ HAM-A or HAM-D scores over the three months (p = 0.211 and p = 0.562, respectively).
Conclusions: ADHD treatment—regardless of medication type—significantly reduces children’s symptom severity and improves caregivers’ QoL. Although anxiety and depression levels in caregivers remained unchanged, QoL improvements are likely due to symptom relief in children. Therefore, the early diagnosis of ADHD and the initiation of treatment as soon as possible are critically important for both reducing the symptoms in children and improving the QoL of their parents.
Keywords
ADHD, Caregivers, Treatment, Quality of Life, Psychological impact
References
- 1. Edition F. Diagnostic and statistical manual of mental disorders. Am Psychiatric Assoc 2013;21:591–643
- 2. Cortese S, Fusetto Veronesi G, Gabellone A, Margari A, Marzulli L, Matera E, et al. The management of sleep disturbances in children with attention-deficit/hyperactivity disorder (ADHD): an update of the literature. Expert Rev Neurother 2024;24:585–96
- 3. Andrade EM, Geha LM, Duran P, Suwwan R, Machado F, do Rosário MC. Quality of life in caregivers of ADHD children and diabetes patients. Front Psychiatry 2016;7:127
- 4. Amerikan Psikiyatri Birliği DSM-V-TR Tanı ölçütleri başvuru kitabı. Çeviren: Ertuğrul Köroğlu. Ankara: HYB Yayıncılık; 2013
- 5. Ma JLC, Lai KYC, Wan ESF, Xia LLL. Multiple family therapy for Chinese families of children with attention deficit hyperactivity disorder (ADHD): treatment efficacy from the children’s perspective and their subjective experiences. J Fam Ther 2019;41:599–619
- 6. Zhao X, Page TF, Altszuler AR, Pelham WE, Kipp H, Gnagy EM, et al. Family Burden of Raising a Child with ADHD. J Abnorm Child Psychol 2019;47:1327–38
- 7. Ahmed MGAE, Felemban EM, El-slamoni MAE fatah A. A comparative study: quality of life, self-competence, and self-liking among the caregivers of children with attention deficit hyperactivity disorder and other non-ADHD children. Middle East Curr Psychiatr 2022;29:27
- 8. Chou WJ, Hsiao RC, Chang CC, Yen CF. Predictors of depressive symptoms in caregivers of children with attention-deficit/hyperactivity disorder: A one-year follow-up study. Int J Environ Res Public Health 2021;18:8835
- 9. Liu TL, Hsiao RC, Chou WJ, Yen CF. Hopelessness in caregivers of children with attention-deficit/hyperactivity disorder: Associations with depression and anxiety and multidimensionally related factors. J Formos Med Assoc 2023;122:1158–64
- 10. Peñuelas-Calvo I, Palomar-Ciria N, Porras-Segovia A, Miguélez-Fernández C, Baltasar-Tello I, Colmenero SP, et al. Impact of ADHD symptoms on family functioning, family burden and parents’ quality of life in a hospital area in Spain. Eur J Psychiatry 2021;35:166–72