USE OF PLANT-DERIVED MATERIALS FOR THE INHIBITION OF QOURUM SENSING MECHANISMS

Year 2021, Volume 46, Issue 2, 256 - 268, 23.03.2021

Gülten GÜNDÜZ Ayça KORKMAZ VURMAZ

https://doi.org/10.15237/gida.GD20134

Abstract

The gene regulation system of microorganisms through a cell density-dependent is controlled by a mechanism called Quorum Sensing. Quorum Sensing (QS) mechanism is a population physiology to control many characteristics regulated phenotypes like exopolysaccharide production, biofilm formation and virulence factor. In recent years, there is an increasing number of researches on the involvement of QS mechanism in the spoilage of food products and food safety. The strategy of inactivation of the QS is called Quorum Quenching (QQ). Studies have shown that QQ mechanism which plays a significant role in the inhibition of microbial growth might provide an alternative strategy to chemical preservatives for improving food safety. Plant-derived materials are promising potential sources of QS inhibitor as they can contain natural antimicrobial substances that inhibit the growth of microorganisms. In this review, the inhibition strategies of quorum sensing mechanism (QQ) by using plant-derived materials are focussed on.

Keywords

Quorum Sensing, Quorum Quenching, plant-drived material, antimicrobial

ÇOĞUNLUK ALGILAMA MEKANİZMASININ İNHİBİSYONUNDA BİTKİSEL MATERYALLERİN KULLANIMI

Abstract

Mikroorganizmaların hücre yoğunluğuna bağlı gen düzenleme sistemi çoğunluk algılama (Quorum Sensing) olarak adlandırılan mekanizma tarafından kontrol edilmektedir. Çoğunluk algılama mekanizması (QS) ekzopolisakkarit üretimi, biyofilm oluşumu ve virülans faktörü gibi popülasyon fizyolojisini düzenleyen fenotipleri kontrol eden mekanizmadır. Son yıllarda gıdaların bozulması ve gıda güvenliği alanlarında QS mekanizmasının rolü üzerine araştırmalar artmıştır. Çoğunluk algılama mekanizmasının inaktivasyonu stratejisine, çoğunluk algılama mekanizmasının inhibisyonu (Quorum Quenching-QQ) adı verilmektedir. Yapılan çalışmalar, QQ mekanizmasının mikrobiyel gelişimin inhibisyonunda önemli bir rol oynadığını ve kimyasal koruyucu yerine gıda güvenliğini arttırmak için alternatif bir strateji olabileceğini göstermiştir. Bitkisel materyaller, mikroorganizmaların gelişimini inhibe edici doğal antimikrobiyel bileşikler içerdikleri için potansiyel QS inhibitörü kaynaklarıdır. Bu derlemede, bitkisel materyaller kullanılarak çoğunluk algılama mekanizmasının inhibisyonu (QQ) stratejilerine odaklanılmıştır.

Keywords

Çoğunluk algılama mekanizması, çoğunluk algılama mekanizmasının inhibisyonu, bitkisel kaynaklı materyal, antimikrobiyel

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