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İNSAN SAĞLIĞI İÇİN RİSK FAKTÖRLERİ OLARAK İÇME SULARINDA ALÜMİNYUM VE FLOR

Year 2022, Volume: 47 Issue: 6, 1005 - 1013, 15.12.2022
https://doi.org/10.15237/gida.GD22085

Abstract

Su kaynakları ve içme suları çeşitli hastalıkları potansiyel olarak etkilemektedir ve çevresel risk faktörleriyle olan ilişkisi halen aydınlatılması gereken gelişmekte olan bir alandır. Çeşitli araştırmalar, suda doğal olarak bulunan elementler olan alüminyum ve florürün, çevresel yönlerden etkilenen içme suyunda artan konsantrasyonla insan sağlığı üzerinde olumsuz bir etki gösterdiğini bildirmiştir. İçme sularındaki yüksek alüminyum seviyelerinin demansa neden olabileceği düşünülmektedir. Birçok çalışma, içme suyundaki alüminyum miktarı ile artan Alzheimer riski arasında bir ilişki bulmuştur. Ayrıca, alüminyum ve florürün absorpsiyonun pozitif bir ilişkiye sahip olduğu ve birlikte daha fazla biyoyararlanıma sahip olduğu düşünülmektedir. Alüminyum ve florürün sağlık üzerindeki etkileri suyun kaynağına, maruz kalma süresine ve vücudun detoks sistemine göre değişiklik gösterebilir. İnsanda yaşamsal faaliyetlerin sağlıklı olması için, içilen içme suyu içeriğinin kontrolünün sağlanması kritik öneme sahiptir. Bu derlemede alüminyum ve florürün insan sağlığı için önemli olan genel özellikleri ve etkileşimleri tartışılacaktır. Bu kimyasalların önemli toksik etkileri göz önünde bulundurularak hastalıklar ve sağlık sorunları arasındaki ilişki değerlendirilecektir.

References

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  • Ahmed, M.F., Mokhtar, M.B., Alam, L. et al. (2019). Non-carcinogenic health risk assessment of aluminum ingestion via drinking water in Malaysia. Expo Health, 11: 167-180.
  • Ahmed Nel, M., Murakami, M., Hirose, Y., Nakashima, M. (2016). Therapeutic potential of dental pulp stem cell secretome for Alzheimer’s disease treatment: an in vitro study. Stem Cells Int, 8102478.
  • Akafu, T., Chimdi, A., Gomoro, K. (2019). Removal of fluoride from drinking water by sorption using diatomite modified with aluminum hydroxide. Journal of Analytical Methods in Chemistry, 3; 2019:4831926.
  • Akinrinade, I. D., Ogundele, O. M., Memudu, A. E., Adefule A. K., Kalejaiye E. D (2013). Degeneration of neuronal cells: A product of fluoride and aluminum assault to the prefrontal cortex. Journal of Cell and Animal Biology, 7(6): 63-66.
  • Akinrinade, I. D., Memudu, A. E., Ogundele, O. M. (2015). Fluoride and aluminum disturb neuronal morphology, transport functions, cholinesterase, lysosomal, and cell cycle activities. Pathophysiology, 22(2): 105-115.
  • Ashrafi, S.D., Jaafari, J., Sattari, L., Esmaeilzadeh, N., Safari, G.H. (2020). Monitoring and health risk assessment of fluoride in drinking water of east Azerbaijan province, Iran. International Journal of Environmental Analytical Chemistry, 1-15.
  • Ateş, M.P., Karaman, Y., Güntekin, S., Ergun, M.A. (2016). Analysis of genetics and risk factors of Alzheimer‘s disease. Neuroscience, 325: 124-131.
  • Bobuş Alkaya, G., Demirci, Ç., Şevik, H. (2022). Aluminum in food and potential role on Alzheimer’s disease of aluminum. Turkish Journal of Engineering, 6 (2), 118-127.
  • Bhatnagar, M. Sukhwal, P., Suhalka, P. Jain, A., Joshi, C., Sharma D. (2011). Effects of fluoride on NADPH-diaphorase neurons in mice forebrain. Research Report Fluoride, 44(4): 195-209.
  • Cao, K., Xiang, J., Dong, Y.T., Xu, Y., Li, Y., Song, H., Zeng, X.X., Ran, L. Y., Hong, W., Guan, Z.Z. (2019). ExposFluoride exposure rates the impairment in learning and memory and neuropathological lesions in mice carrying the APP/PS1 double-transgenic mutation. Alzheimer's Research & Therapy, 11(1): 35.
  • Chen, X., Zhang, M., Ahmed, M., Surapaneni, K. M., Veeraraghavan, V. P., Arulselvan, P. (2021). Neuroprotective effects of ononin against the aluminium chloride-induced Alzheimer’s disease in rats. Saudi Journal of Biological Sciences. 28(8): 4232-4239.
  • Choi, A. L., Zhang, Y., Sun, G., Bellinger, D. C., Wang, K., Yang, X. J., Grandjean, P. (2015). Association of lifetime exposure to fluoride and cognitive functions in Chinese children: A pilot study. Neurotoxicology and Teratology, 47: 96-101.
  • Das, N., Raymick, J., Sarkar, S. (2021). Role of metals in Alzheimer’s disease. Metab Brain Dis, 36: 1627-1639.
  • Davoudi, M., Barjasteh-Askari, F., Sarmadi, M., Ghorbani, M., Yaseri, M., Bazrafshan, E., Mahvi, A. H., Moohebati, M. (2021). Relationship of fluoride in drinking water with blood pressure and essential hypertension prevalence: A systematic review and meta-analysis. International Archives of Occupational and Environmental Health, 94(6): 1137-1146.
  • Dey, M., Singh, R.K. (2022). Neurotoxic effects of aluminum exposure as a potential risk factor for Alzheimer’s disease. Pharmacol. Rep., 74: 439-450.
  • Dick, B.A., Ammar, M. B., Sidi Y.M., Mohamed E. (2021). Evaluation of Aluminum Levels in Drinking Water of Nouakchott. Journal of Pharmacy and Pharmacology 9:210-213.
  • EFSA (European Food Safety Authority). (2008). Safety of aluminum from dietary intake, scientific opinion of the panel on food additives, flavorings, processing aids, and food contact materials (AFC) EFSA Journal. 1-34.
  • Everett, E.T. (2011). Fluoride's effects on the formation of teeth and bones, and the influence of genetics. Journal of Dental Research, 90(5): 552-560.
  • Farhat, S.M., Ali M. (2020). The concentration of aluminum in the drinking water of Pakistan and its implications on human health. Life and Science, 1(2): 77-82.
  • Flaten, T.P. (2001). Aluminum is a risk factor for Alzheimer’s disease, with emphasis on drinking water. Brain Research Bulletin, 55(2): 187-196.
  • Gara, T., Fengting, L., Nhapi, I. Clifton, M., Webster, G. (2018). Health safety of drinking water supplied in Africa: A Closer look using applicable water-quality standards as a measure. Expo Health, 10: 117-128.
  • Ghaffari, H.R., Kamari, Z., Ranaei, V., Pilevar, Z., Akbari, M., Moridi, M., Mohamed Khedher, K., Thai, V. N., Fakhri, Y., Khaneghah, A.M. (2021). The concentration of potentially hazardous elements (PHEs) in drinking water and non-carcinogenic risk assessment: A case study in Bandar Abbas, Iran. Environmental Research, 201-1111567.
  • Hasan, M. K., Alam, S., Mirkovic, J., Hossain, M. F. (2018). Screening of human proteins for fluoride and aluminum binding. Bioinformation, 14(2): 68-74.
  • He, Y., Pan, L., Chen, R., Shi, B. (2021). Field studies of aluminum release and deposition in drinking water distribution systems. Chemosphere, 275, 130067.
  • Indermitte, E., Saava, A., Karro, E. (2014). Reducing exposure to high fluoride drinking water in the Estonia-a countrywide study. International Journal of Environmental Research and Public Health, 11: 3132-3142.
  • Inan-Eroglu, E., Ayaz, A. (2018). Is aluminum exposure a risk factor for neurological disorders? Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences, 23: 51.
  • Jiang, G., Jin, L., Pan, Q., Peng, N., Meng, Y., Huang L., Wang H., (2022). Structural modification of aluminum oxides for removing fluoride in water: crystal forms and metal ion doping, Environmental Technology, 43:21, 3248-3261.
  • Khairul Zaman, N., Rohani, R., Izni Yusoff, I., Kamsol, M.A., Basiron, S.A., Abd. Rashid, A.I. (2021). Reply to Ivy et al. Comment on “Khairul Zaman et al. Eco-Friendly Coagulant versus Industrially Used Coagulants: Identification of Their Coagulation Performance, Mechanism and Optimization in Water Treatment Process. Int. J. Environ. Res. Public Health 2021, 18, 9164”. Int. J. Environ. Res. Public Health, 18, 12716.
  • KheradPisheh, Z., Ehrampoush, M.H., Montazeri, A., Mirzaei, M., Mokhtari, M., Mahvi A.H. (2016). Fluoride in drinking water in 31 provinces of Iran. Expo Health, 8: 465-474.
  • Klotz, K., Weistenhöfer, W., Neff, F., Hartwig, A., van Thriel, C., Drexler, H. (2017). The health effects of aluminum exposure. Deutsches Arzteblatt International, 114(39): 653-659. Kinawy A. A. (2019). Synergistic oxidative impact of aluminum chloride and sodium fluoride exposure during early stages of brain development in the rat. Environmental Science and Pollution Research International, 26(11): 10951-10960.
  • Korabecny., J, Zemek., F, Soukup., O, Spilovska., K, Musilek., K, Jun., D, Nepovimova., E, Kuca., K. (2014). Pharmacotherapy of Alzheimer’s disease: Current state and future perspectives. In: Drug design and discovery in Alzheimer's Disease Ed.: Atta ur, R. Choudhary, M. I.: Elsevier. 3-39.
  • Krause, B.C., Kriegel, F.L., Rosenkranz, D. (2020). Aluminum and aluminum oxide nanomaterials uptake after oral exposure - a comparative study. Sci Rep. 10:2698
  • Krupińska, I. (2020). Aluminum drinking water treatment residuals and their toxic impact on human health. Molecules (Basel, Switzerland), 25(3): 641.
  • Letzel, M., Drexler, H., Göen, T., Hiller, J. (2020). Impact of daily antiperspirant use on the systemic aluminum exposure: An experimental intervention study. Skin Pharmacol Physiol, 33(1): 1-8.
  • Li, M., Cheng J., Zou F., (2021). Effects of pre-oxidation on residual dissolved aluminum in coagulated water: A pilot-scale study. Water Research. 190:116682. DOI: 10.1016/j.watres.2020.116682. PMID: 33279751.
  • Lim, W.L.K., Chung, E.C.Y., Chong, C.H., Ong, N.T.K., Hew, W.S., Kahar, N.B., Goh, Z.J. (2018). Removal of fluoride and aluminum using plant-based coagulants wrapped with a fibrous thin film. Process Safety and Environmental Protection, 117: 704-710. Martyn, C.N., Barker, D.J., Osmond, C., Harris, E.C., Edwardson, J.A., Lacey, R.F. (1989). Geographical relation between Alzheimer's disease and aluminum in drinking water. Lancet (London, England), 1(8629): 59-62.
  • Mcdonald, J.B., Dhakal, S., Macreadie, I. (2021). A Toxic Synergy between Aluminium and Amyloid Beta in Yeast. International Journal of Molecular Sciences, 22(4): 1835.
  • McLachlan, D.R., Bergeron, C., Smith, J.E., Boomer, D., Rifat, S.L. (1996). Risk for neuropathologically confirmed Alzheimer's disease and residual aluminum in municipal drinking water employing weighted residential histories. Neurology, 46(2): 401-405.
  • Mehany, H., El-Shafai, N., Attia, A., Ibrahim, M., El-Mehasseb, I. (2022). Potential of chitosan nanoparticle/fluoride nanocomposite for reducing the toxicity of fluoride an in-vivo study on the rat heart functions: Hematopoietic and immune systems. International Journal of Biological Macromolecules. 216-10.16.
  • Pang, T., Aye Chan, T. S., Jande, Y., Shen, J. (2020). Removal of fluoride from water using activated carbon fibers modified with zirconium by a drop-coating method. Chemosphere, 255: 126950.
  • Papadimitriou, C., Celikkaya, H., Cosacak, M.I., Mashkaryan, V., Bray, L., Bhattarai, P., Brandt, K., Hollak, H., Chen, X., He, S., Antos, C.L., Lin, W., Thomas, A.K., Dahl, A., Kurth, T., Friedrichs, J., Zhang, Y., Freudenberg, U., Werner C., Kizil, C. (2018). 3D culture method for Alzheimer's disease modeling reveals Interleukin-4 rescues Abeta42-induced loss of human neural stem cell plasticity. Developmental Cell, 46(1): 85-101.
  • Rondeau, V., Jacqmin-Gadda, H., Commenges, D., Helmer, C., Dartigues, J.F. (2009). Aluminum and silica in drinking water and the risk of Alzheimer's disease or cognitive decline: findings from a 15-year follow-up of the PAQUID cohort. American Journal of Epidemiology, 169(4): 489-496.
  • Russ, T. C., Killin, L., Hannah, J., Batty, G. D., Deary, I. J., Starr, J. M. (2020). Aluminum and fluoride in drinking water in relation to later dementia risk. The British Journal of Psychiatry: the Journal of Mental Science, 216(1): 29-34.
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ALUMINIUM AND FLUORINE IN DRINKING WATER AS RISK FACTORS FOR HUMAN HEALTH

Year 2022, Volume: 47 Issue: 6, 1005 - 1013, 15.12.2022
https://doi.org/10.15237/gida.GD22085

Abstract

Drinking water potentially affects a variety of diseases, and their relationship to environmental risk factors is an emerging area that still needs to be clarified. Studies have reported that aluminum and fluoride, elements naturally found in water, have an adverse effect on human health with increasing concentration in drinking water, which is affected by environmental aspects. High aluminum levels in drinking water can cause dementia. Many studies have found an association between the amount of aluminum in drinking water and an increased risk of Alzheimer's. The absorption of aluminum and fluoride is thought to have a positive relationship and together have greater bioavailability. The health effects of aluminum and fluoride can vary depending on the source of the water, the duration of exposure, and the body's detox system. It is crucial to control the content of drinking water in order for humans' vital activities to be healthy. In this review, the general properties and interactions of aluminum and fluoride, which are important for human health, will be discussed. Considering the important toxic effects of these chemicals, the relationship between diseases and health problems will be evaluated.

References

  • Aghaei, M., Karimzade, S., Yaseri, M., Khorsandi, H., Zolfi, E., Mahvi, A. H. (2015). Hypertension and fluoride in drinking water: A case study from West Azerbaijan, Iran. Fluoride, 48(3): 252-258.
  • Ahmed, M.F., Mokhtar, M.B., Alam, L. et al. (2019). Non-carcinogenic health risk assessment of aluminum ingestion via drinking water in Malaysia. Expo Health, 11: 167-180.
  • Ahmed Nel, M., Murakami, M., Hirose, Y., Nakashima, M. (2016). Therapeutic potential of dental pulp stem cell secretome for Alzheimer’s disease treatment: an in vitro study. Stem Cells Int, 8102478.
  • Akafu, T., Chimdi, A., Gomoro, K. (2019). Removal of fluoride from drinking water by sorption using diatomite modified with aluminum hydroxide. Journal of Analytical Methods in Chemistry, 3; 2019:4831926.
  • Akinrinade, I. D., Ogundele, O. M., Memudu, A. E., Adefule A. K., Kalejaiye E. D (2013). Degeneration of neuronal cells: A product of fluoride and aluminum assault to the prefrontal cortex. Journal of Cell and Animal Biology, 7(6): 63-66.
  • Akinrinade, I. D., Memudu, A. E., Ogundele, O. M. (2015). Fluoride and aluminum disturb neuronal morphology, transport functions, cholinesterase, lysosomal, and cell cycle activities. Pathophysiology, 22(2): 105-115.
  • Ashrafi, S.D., Jaafari, J., Sattari, L., Esmaeilzadeh, N., Safari, G.H. (2020). Monitoring and health risk assessment of fluoride in drinking water of east Azerbaijan province, Iran. International Journal of Environmental Analytical Chemistry, 1-15.
  • Ateş, M.P., Karaman, Y., Güntekin, S., Ergun, M.A. (2016). Analysis of genetics and risk factors of Alzheimer‘s disease. Neuroscience, 325: 124-131.
  • Bobuş Alkaya, G., Demirci, Ç., Şevik, H. (2022). Aluminum in food and potential role on Alzheimer’s disease of aluminum. Turkish Journal of Engineering, 6 (2), 118-127.
  • Bhatnagar, M. Sukhwal, P., Suhalka, P. Jain, A., Joshi, C., Sharma D. (2011). Effects of fluoride on NADPH-diaphorase neurons in mice forebrain. Research Report Fluoride, 44(4): 195-209.
  • Cao, K., Xiang, J., Dong, Y.T., Xu, Y., Li, Y., Song, H., Zeng, X.X., Ran, L. Y., Hong, W., Guan, Z.Z. (2019). ExposFluoride exposure rates the impairment in learning and memory and neuropathological lesions in mice carrying the APP/PS1 double-transgenic mutation. Alzheimer's Research & Therapy, 11(1): 35.
  • Chen, X., Zhang, M., Ahmed, M., Surapaneni, K. M., Veeraraghavan, V. P., Arulselvan, P. (2021). Neuroprotective effects of ononin against the aluminium chloride-induced Alzheimer’s disease in rats. Saudi Journal of Biological Sciences. 28(8): 4232-4239.
  • Choi, A. L., Zhang, Y., Sun, G., Bellinger, D. C., Wang, K., Yang, X. J., Grandjean, P. (2015). Association of lifetime exposure to fluoride and cognitive functions in Chinese children: A pilot study. Neurotoxicology and Teratology, 47: 96-101.
  • Das, N., Raymick, J., Sarkar, S. (2021). Role of metals in Alzheimer’s disease. Metab Brain Dis, 36: 1627-1639.
  • Davoudi, M., Barjasteh-Askari, F., Sarmadi, M., Ghorbani, M., Yaseri, M., Bazrafshan, E., Mahvi, A. H., Moohebati, M. (2021). Relationship of fluoride in drinking water with blood pressure and essential hypertension prevalence: A systematic review and meta-analysis. International Archives of Occupational and Environmental Health, 94(6): 1137-1146.
  • Dey, M., Singh, R.K. (2022). Neurotoxic effects of aluminum exposure as a potential risk factor for Alzheimer’s disease. Pharmacol. Rep., 74: 439-450.
  • Dick, B.A., Ammar, M. B., Sidi Y.M., Mohamed E. (2021). Evaluation of Aluminum Levels in Drinking Water of Nouakchott. Journal of Pharmacy and Pharmacology 9:210-213.
  • EFSA (European Food Safety Authority). (2008). Safety of aluminum from dietary intake, scientific opinion of the panel on food additives, flavorings, processing aids, and food contact materials (AFC) EFSA Journal. 1-34.
  • Everett, E.T. (2011). Fluoride's effects on the formation of teeth and bones, and the influence of genetics. Journal of Dental Research, 90(5): 552-560.
  • Farhat, S.M., Ali M. (2020). The concentration of aluminum in the drinking water of Pakistan and its implications on human health. Life and Science, 1(2): 77-82.
  • Flaten, T.P. (2001). Aluminum is a risk factor for Alzheimer’s disease, with emphasis on drinking water. Brain Research Bulletin, 55(2): 187-196.
  • Gara, T., Fengting, L., Nhapi, I. Clifton, M., Webster, G. (2018). Health safety of drinking water supplied in Africa: A Closer look using applicable water-quality standards as a measure. Expo Health, 10: 117-128.
  • Ghaffari, H.R., Kamari, Z., Ranaei, V., Pilevar, Z., Akbari, M., Moridi, M., Mohamed Khedher, K., Thai, V. N., Fakhri, Y., Khaneghah, A.M. (2021). The concentration of potentially hazardous elements (PHEs) in drinking water and non-carcinogenic risk assessment: A case study in Bandar Abbas, Iran. Environmental Research, 201-1111567.
  • Hasan, M. K., Alam, S., Mirkovic, J., Hossain, M. F. (2018). Screening of human proteins for fluoride and aluminum binding. Bioinformation, 14(2): 68-74.
  • He, Y., Pan, L., Chen, R., Shi, B. (2021). Field studies of aluminum release and deposition in drinking water distribution systems. Chemosphere, 275, 130067.
  • Indermitte, E., Saava, A., Karro, E. (2014). Reducing exposure to high fluoride drinking water in the Estonia-a countrywide study. International Journal of Environmental Research and Public Health, 11: 3132-3142.
  • Inan-Eroglu, E., Ayaz, A. (2018). Is aluminum exposure a risk factor for neurological disorders? Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences, 23: 51.
  • Jiang, G., Jin, L., Pan, Q., Peng, N., Meng, Y., Huang L., Wang H., (2022). Structural modification of aluminum oxides for removing fluoride in water: crystal forms and metal ion doping, Environmental Technology, 43:21, 3248-3261.
  • Khairul Zaman, N., Rohani, R., Izni Yusoff, I., Kamsol, M.A., Basiron, S.A., Abd. Rashid, A.I. (2021). Reply to Ivy et al. Comment on “Khairul Zaman et al. Eco-Friendly Coagulant versus Industrially Used Coagulants: Identification of Their Coagulation Performance, Mechanism and Optimization in Water Treatment Process. Int. J. Environ. Res. Public Health 2021, 18, 9164”. Int. J. Environ. Res. Public Health, 18, 12716.
  • KheradPisheh, Z., Ehrampoush, M.H., Montazeri, A., Mirzaei, M., Mokhtari, M., Mahvi A.H. (2016). Fluoride in drinking water in 31 provinces of Iran. Expo Health, 8: 465-474.
  • Klotz, K., Weistenhöfer, W., Neff, F., Hartwig, A., van Thriel, C., Drexler, H. (2017). The health effects of aluminum exposure. Deutsches Arzteblatt International, 114(39): 653-659. Kinawy A. A. (2019). Synergistic oxidative impact of aluminum chloride and sodium fluoride exposure during early stages of brain development in the rat. Environmental Science and Pollution Research International, 26(11): 10951-10960.
  • Korabecny., J, Zemek., F, Soukup., O, Spilovska., K, Musilek., K, Jun., D, Nepovimova., E, Kuca., K. (2014). Pharmacotherapy of Alzheimer’s disease: Current state and future perspectives. In: Drug design and discovery in Alzheimer's Disease Ed.: Atta ur, R. Choudhary, M. I.: Elsevier. 3-39.
  • Krause, B.C., Kriegel, F.L., Rosenkranz, D. (2020). Aluminum and aluminum oxide nanomaterials uptake after oral exposure - a comparative study. Sci Rep. 10:2698
  • Krupińska, I. (2020). Aluminum drinking water treatment residuals and their toxic impact on human health. Molecules (Basel, Switzerland), 25(3): 641.
  • Letzel, M., Drexler, H., Göen, T., Hiller, J. (2020). Impact of daily antiperspirant use on the systemic aluminum exposure: An experimental intervention study. Skin Pharmacol Physiol, 33(1): 1-8.
  • Li, M., Cheng J., Zou F., (2021). Effects of pre-oxidation on residual dissolved aluminum in coagulated water: A pilot-scale study. Water Research. 190:116682. DOI: 10.1016/j.watres.2020.116682. PMID: 33279751.
  • Lim, W.L.K., Chung, E.C.Y., Chong, C.H., Ong, N.T.K., Hew, W.S., Kahar, N.B., Goh, Z.J. (2018). Removal of fluoride and aluminum using plant-based coagulants wrapped with a fibrous thin film. Process Safety and Environmental Protection, 117: 704-710. Martyn, C.N., Barker, D.J., Osmond, C., Harris, E.C., Edwardson, J.A., Lacey, R.F. (1989). Geographical relation between Alzheimer's disease and aluminum in drinking water. Lancet (London, England), 1(8629): 59-62.
  • Mcdonald, J.B., Dhakal, S., Macreadie, I. (2021). A Toxic Synergy between Aluminium and Amyloid Beta in Yeast. International Journal of Molecular Sciences, 22(4): 1835.
  • McLachlan, D.R., Bergeron, C., Smith, J.E., Boomer, D., Rifat, S.L. (1996). Risk for neuropathologically confirmed Alzheimer's disease and residual aluminum in municipal drinking water employing weighted residential histories. Neurology, 46(2): 401-405.
  • Mehany, H., El-Shafai, N., Attia, A., Ibrahim, M., El-Mehasseb, I. (2022). Potential of chitosan nanoparticle/fluoride nanocomposite for reducing the toxicity of fluoride an in-vivo study on the rat heart functions: Hematopoietic and immune systems. International Journal of Biological Macromolecules. 216-10.16.
  • Pang, T., Aye Chan, T. S., Jande, Y., Shen, J. (2020). Removal of fluoride from water using activated carbon fibers modified with zirconium by a drop-coating method. Chemosphere, 255: 126950.
  • Papadimitriou, C., Celikkaya, H., Cosacak, M.I., Mashkaryan, V., Bray, L., Bhattarai, P., Brandt, K., Hollak, H., Chen, X., He, S., Antos, C.L., Lin, W., Thomas, A.K., Dahl, A., Kurth, T., Friedrichs, J., Zhang, Y., Freudenberg, U., Werner C., Kizil, C. (2018). 3D culture method for Alzheimer's disease modeling reveals Interleukin-4 rescues Abeta42-induced loss of human neural stem cell plasticity. Developmental Cell, 46(1): 85-101.
  • Rondeau, V., Jacqmin-Gadda, H., Commenges, D., Helmer, C., Dartigues, J.F. (2009). Aluminum and silica in drinking water and the risk of Alzheimer's disease or cognitive decline: findings from a 15-year follow-up of the PAQUID cohort. American Journal of Epidemiology, 169(4): 489-496.
  • Russ, T. C., Killin, L., Hannah, J., Batty, G. D., Deary, I. J., Starr, J. M. (2020). Aluminum and fluoride in drinking water in relation to later dementia risk. The British Journal of Psychiatry: the Journal of Mental Science, 216(1): 29-34.
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There are 53 citations in total.

Details

Primary Language English
Subjects Food Engineering
Journal Section Articles
Authors

Fatma Özsel Araç 0000-0002-4668-5880

Ozan Aldemir 0000-0002-0199-5674

Early Pub Date October 19, 2022
Publication Date December 15, 2022
Published in Issue Year 2022 Volume: 47 Issue: 6

Cite

APA Araç, F. Ö., & Aldemir, O. (2022). ALUMINIUM AND FLUORINE IN DRINKING WATER AS RISK FACTORS FOR HUMAN HEALTH. Gıda, 47(6), 1005-1013. https://doi.org/10.15237/gida.GD22085
AMA Araç FÖ, Aldemir O. ALUMINIUM AND FLUORINE IN DRINKING WATER AS RISK FACTORS FOR HUMAN HEALTH. The Journal of Food. December 2022;47(6):1005-1013. doi:10.15237/gida.GD22085
Chicago Araç, Fatma Özsel, and Ozan Aldemir. “ALUMINIUM AND FLUORINE IN DRINKING WATER AS RISK FACTORS FOR HUMAN HEALTH”. Gıda 47, no. 6 (December 2022): 1005-13. https://doi.org/10.15237/gida.GD22085.
EndNote Araç FÖ, Aldemir O (December 1, 2022) ALUMINIUM AND FLUORINE IN DRINKING WATER AS RISK FACTORS FOR HUMAN HEALTH. Gıda 47 6 1005–1013.
IEEE F. Ö. Araç and O. Aldemir, “ALUMINIUM AND FLUORINE IN DRINKING WATER AS RISK FACTORS FOR HUMAN HEALTH”, The Journal of Food, vol. 47, no. 6, pp. 1005–1013, 2022, doi: 10.15237/gida.GD22085.
ISNAD Araç, Fatma Özsel - Aldemir, Ozan. “ALUMINIUM AND FLUORINE IN DRINKING WATER AS RISK FACTORS FOR HUMAN HEALTH”. Gıda 47/6 (December 2022), 1005-1013. https://doi.org/10.15237/gida.GD22085.
JAMA Araç FÖ, Aldemir O. ALUMINIUM AND FLUORINE IN DRINKING WATER AS RISK FACTORS FOR HUMAN HEALTH. The Journal of Food. 2022;47:1005–1013.
MLA Araç, Fatma Özsel and Ozan Aldemir. “ALUMINIUM AND FLUORINE IN DRINKING WATER AS RISK FACTORS FOR HUMAN HEALTH”. Gıda, vol. 47, no. 6, 2022, pp. 1005-13, doi:10.15237/gida.GD22085.
Vancouver Araç FÖ, Aldemir O. ALUMINIUM AND FLUORINE IN DRINKING WATER AS RISK FACTORS FOR HUMAN HEALTH. The Journal of Food. 2022;47(6):1005-13.

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