Sublethal Exposure and Toxicity Effect of Propanil on Hematology and Serum Biochemistry in Oreochromis niloticus in a Static Bioassay

Abstract

Herbicide Propanil is a toxicant that can adversely affect the health of fish. The present study was conducted to ascertain the toxicity effect of Propanil on hematology and serum biochemistry in Oreochromis niloticus juvenile. Fish specimens were exposed to sub-lethal concentrations (0.0, 0.22, 0.44 and 0.87 mg/L) of Propanil derived from the 96hour Lethal concentration for eight weeks. Fish specimens were sampled for hematological and biochemical analysis at 2, 6 and 8 week’s duration exposure. Significant changes and dose dependent decreases in red blood cell, pack cell volume, hemoglobin values were observed in Propanil exposed fish compared to the control. Progressive increase in white blood cell count and leukocyte differentials (neutrophils and lymphocytes) were found in Propanil exposed fish compared to the control. Significant increases in biochemical parameters (glucose, protein, triglycerides, glutamic oxalo-acetic transminase and glutamate pyruvate transaminase) were observed in Propanil exposed fish groups compared to the control. However, cholesterol levels decreased significantly except for 8th week Propanil duration exposure. Findings of the present study revealed that Propanil adversely affected fish health.

Keywords

• Toxicity,Biochemistry,Propanil,Hematology,Biochemistry,Oreochromis niloticus

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