Research Article

Analyzing the Competition of HIV-1 Phenotypes with Quantum Game Theory

Volume: 35 Number: 3 September 1, 2022
EN

Analyzing the Competition of HIV-1 Phenotypes with Quantum Game Theory

Abstract

HIV-1 (Human Immunodeficiency Virus) is a virus that causes AIDS (Acquired Immunodeficiency Syndrome), which damages the immune system by reducing people's resistance to infections and diseases. Antiretroviral treatment methods are based on drug designs developed using inhibitors that suppress the dynamics that enable the maturation of the virus. However, studies are needed to improve treatment methods against infection because HIV-1 is frequently mutated and mutant viruses develop resistance to the treatment used. Therefore, it is important to model the evolutionary development of the virus. For this purpose, the developmental process and spread of HIV-1 are modeled as a game with the players of phenotypes in this study. The related searches known to be made so far have been carried out based on the rules of classical physics. However, games of survival are being played on the molecular level, where the rules of quantum mechanics work. Since the HIV-1 game is being played on the molecular level, the behaviors of the virus phenotypes are examined from the perspective of quantum computation.

Keywords

References

  1. [1] Castiglione, F., Pappalardo, F., Bernasch, M. and Motta, S., “Optimization of haart with genetic algorithms and agent-based models of hiv infection”, Bioinformatics, 23(24): 3350-3355, (2007).
  2. [2] Harada, K., “Self-destruction Dynamics of HIV-1 Quasi-species Population in the Presence of Mutagenic Activities”, Procedia Computer Science, 22: 1259-1265, (2013).
  3. [3] Goshu, A.T. and Dessie, Z.G., “Modelling Progression of HIV/AIDS Disease Stages Using Semi-Markov Processes”, Journal of Data Science, 11: 269-280, (2013).
  4. [4] Wu, Y., Zhang, M., Wu, J., Zhao, X. and Xia, L., “Evolutionary game theoretic strategy for optimal drug delivery to influence selection pressure in treatment of HIV-1”, Journal of Mathematical Biology, 3(64): 495-512, (2012).
  5. [5] Khazaei, B., Sartakhti, J.S., Manshaei, M.H., Zhu, Q., Sadeghi, M. and Mousavi, S.R., “HIV-1 infected T-cells dynamics and prognosis: An evolutionary game theory model”, Computer Methods and Programs in Biomedicine, 152: 1-14, (2017).
  6. [6] Fisher, R. A., The Genetical Theory of Natural Selection, 1st ed., Oxford Clarendon Press, Oxford, (1930).
  7. [7] Hidalgo, E.G., “Quantum Games and the Relationships between Quantum Mechanics and Game Theory”, arXiv:0803.0292v2 [quant-ph], (2016).
  8. [8] Smith, J.M., Evolution and the Theory of Games, 1st ed., Cambridge University Press, Oxford, (1982).

Details

Primary Language

English

Subjects

Engineering

Journal Section

Research Article

Publication Date

September 1, 2022

Submission Date

July 21, 2020

Acceptance Date

September 15, 2021

Published in Issue

Year 2022 Volume: 35 Number: 3

APA
Özlüer Başer, B. (2022). Analyzing the Competition of HIV-1 Phenotypes with Quantum Game Theory. Gazi University Journal of Science, 35(3), 1190-1198. https://doi.org/10.35378/gujs.772616
AMA
1.Özlüer Başer B. Analyzing the Competition of HIV-1 Phenotypes with Quantum Game Theory. Gazi University Journal of Science. 2022;35(3):1190-1198. doi:10.35378/gujs.772616
Chicago
Özlüer Başer, Bilge. 2022. “Analyzing the Competition of HIV-1 Phenotypes With Quantum Game Theory”. Gazi University Journal of Science 35 (3): 1190-98. https://doi.org/10.35378/gujs.772616.
EndNote
Özlüer Başer B (September 1, 2022) Analyzing the Competition of HIV-1 Phenotypes with Quantum Game Theory. Gazi University Journal of Science 35 3 1190–1198.
IEEE
[1]B. Özlüer Başer, “Analyzing the Competition of HIV-1 Phenotypes with Quantum Game Theory”, Gazi University Journal of Science, vol. 35, no. 3, pp. 1190–1198, Sept. 2022, doi: 10.35378/gujs.772616.
ISNAD
Özlüer Başer, Bilge. “Analyzing the Competition of HIV-1 Phenotypes With Quantum Game Theory”. Gazi University Journal of Science 35/3 (September 1, 2022): 1190-1198. https://doi.org/10.35378/gujs.772616.
JAMA
1.Özlüer Başer B. Analyzing the Competition of HIV-1 Phenotypes with Quantum Game Theory. Gazi University Journal of Science. 2022;35:1190–1198.
MLA
Özlüer Başer, Bilge. “Analyzing the Competition of HIV-1 Phenotypes With Quantum Game Theory”. Gazi University Journal of Science, vol. 35, no. 3, Sept. 2022, pp. 1190-8, doi:10.35378/gujs.772616.
Vancouver
1.Bilge Özlüer Başer. Analyzing the Competition of HIV-1 Phenotypes with Quantum Game Theory. Gazi University Journal of Science. 2022 Sep. 1;35(3):1190-8. doi:10.35378/gujs.772616