Anti-genotoxic Effects of Schiff bases and their Mn(III) Complexes Containing L-Aspartic acid and L-Phenylalanine

Year 2018, Volume: 31 Issue: 2, 408 - 414, 01.06.2018

Elvan Hasanoğlu Özkan , Hamit Emre Kızıl İffet Şakıyan Dilek Nartop , Nurşen Sarı , Güleray Ağar

Abstract

The purpose of the research
was to evaluate the genotoxic and anti-genotoxic properties of Schiff bases and their Mn (III) complexes containing
L-aspartic acid, and L-phenylalanine. The
anti-genotoxic properties of four compounds in human lymphocytes cells were
investigated by sister chromatid exchanges (SCEs) test system against aflatoxin
B₁ (AFB₁). The results showed that compounds
have strong anti-genotoxic properties.

 

Keywords

Aflatoxin Bı, Mn(III) complexes, mutagenicity

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