Research Article

Enhancing Multi-Disease Prediction with Machine Learning: A Comparative Analysis and Hyperparameter Optimization Approach

Volume: 13 Number: 1 March 24, 2025
EN

Enhancing Multi-Disease Prediction with Machine Learning: A Comparative Analysis and Hyperparameter Optimization Approach

Abstract

Although traditional methods based on statistical parameters are still important in healthcare, Machine learning (ML) algorithms offer promising results for analyzing health data. Therefore, the presented work aimed to evaluate the success of several supervised ML models with hyperparameter optimization (HPO) for predicting multiple diseases such as diabetes, heart disease, Parkinson's disease, and breast cancer. We evaluated seven distinct algorithms: Logistic Regression (LR), Gradient Boosting (GB), k-Nearest Neighbors (k-NN), Extreme Gradient Boosting (XGB), Support Vector Machines (SVM), Random Forests (RF), and a basic "nonlinear mapping technique". Each algorithm was trained and compared in isolation for each targeted health condition. The success of these techniques was assessed using standard performance metrics like accuracy, precision, F1-score, and recall. Additionally, hyperparameter optimization was applied to each algorithm and its effect on the result was observed. The results show the potential of ML for multiple disease prediction with individual models achieving high accuracy for specific diseases. SVM achieved 100% accuracy for heart disease, Gradient Boosting achieved 90% for diabetes, a simple Neural Network achieved 99% for breast cancer, and Random Forest achieved 100% for Parkinson's disease. These results emphasize the importance of selecting appropriate models for specific disease prediction tasks. A web-based application has been developed so that users can easily use the models by selecting a disease, providing relevant input, and receiving a prediction based on the chosen model. In conclusion, this study highlights the potential of machine learning and hyperparameter optimization for multi-disease prediction and underlines the importance of model selection.

Keywords

Supporting Institution

Karabuk University Scientific Research Projects Coordination Department

Project Number

KBÜBAP-24-YL-065

Ethical Statement

There is no conflict of interest between the authors.

Thanks

This study was supported with the project code: KBÜBAP-24-YL-065 under the program of “Karabuk University Scientific Research Projects Coordination Department”.

References

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Details

Primary Language

English

Subjects

Biomedical Diagnosis

Journal Section

Research Article

Early Pub Date

February 20, 2025

Publication Date

March 24, 2025

Submission Date

May 26, 2024

Acceptance Date

February 9, 2025

Published in Issue

Year 2025 Volume: 13 Number: 1

APA
Bechir, M. K., & Atasoy, F. (2025). Enhancing Multi-Disease Prediction with Machine Learning: A Comparative Analysis and Hyperparameter Optimization Approach. Gazi Üniversitesi Fen Bilimleri Dergisi Part C: Tasarım Ve Teknoloji, 13(1), 367-381. https://doi.org/10.29109/gujsc.1489959

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