The Effects of High Intensive Interval Training (HIIT) on Brain-Derived Neurotrophic Factor (BDNF) and Cardiovascular Health: A Review

Serdar Bayrakdaroğlu; Nuri Topsakal; Özgür Eken

doi:10.37989/gumussagbil.1052230

Review

The Effects of High Intensive Interval Training (HIIT) on Brain-Derived Neurotrophic Factor (BDNF) and Cardiovascular Health: A Review

Year 2022, Volume: 11 Issue: 1, 346 - 354, 19.03.2022

Serdar Bayrakdaroğlu Nuri Topsakal Özgür Eken

https://doi.org/10.37989/gumussagbil.1052230

Cited By: 2

Abstract

High-intensity interval training (HIIT) programs have lately gained popularity because they produce beneficial adaptations for both inactive and athletes, as well as positive health and performance benefits and time efficiency. Therefore, it was purposed to review scientific research results about the effects of HIIT programs on BDNF and cardiovascular health. Although there are research findings suggesting that HIIT may be an effective strategy for promoting elevation of BDNF concentrations, current research seems to be rather limited and inconclusive. It can be thought that exercise intensity is a factor affecting BDNF activation. In healthy people, there seems to be a positive linear relationship between exercise intensity and BDNF levels of acute exercise. However, further experimental studies are needed to elucidate the effect of HIIT on BDNF in humans with metabolic or cardiovascular diseases. However, it can be suggested that high intensity can be an significant achievement factor to design an effective exercise programs and the HIIT methodology has a critical importance for improving cardiovascular function, particularly in healthy individuals. In conclusion, while existing studies show that high-intensity interval training (HIIT) programs can improve cardiovascular health in some populations, further scientific research is needed to determine the efficiency of this strategy in producing physiological adaptation to exercise.

Keywords

High intensity interval training (HIIT), BDNF, Cardiovascular health

References

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Yüksek Şiddetli İnterval Antrenmanların (HIIT) Beyin Kaynaklı Nörotrofik Faktör (BDNF) ve Kardiyovasküler Sağlık Üzerine Etkileri: Derleme

Year 2022, Volume: 11 Issue: 1, 346 - 354, 19.03.2022

Serdar Bayrakdaroğlu Nuri Topsakal Özgür Eken

https://doi.org/10.37989/gumussagbil.1052230

Cited By: 2

Abstract

Yüksek şiddetli interval antrenman (HIIT) programları son zamanlarda hem sedanterler hem de sporcular açısından pozitif adaptasyonlar sağlaması, sağlık ve performans açısından olumlu katkılar sunması, zamansal açıdan verim sağlamasından dolayı popülaritesi giderek artmıştır. Bu noktadan hareketle araştırmada HIIT metadolojisinin BDNF ve kardiyovasküler sağlık üzerindeki etkileri hakkında bilimsel araştırma sonuçlarının derlenmesi amaçlanmıştır. HIIT'in BDNF seviyesini arttırmak için etkili bir stratejisi olabileceğini gösteren araştırma sonuçları olmasına rağmen, mevcut araştırmaların oldukça sınırlı ve yetersiz olduğu görülmektedir. Egzersiz yoğunluğunun BDNF aktivasyonunu etkileyen bir unsur olduğu düşünülebilir. Sağlıklı insanlarda, egzersiz şiddeti ile BDNF seviyeleri arasında doğrusal bir ilişki olduğu görülmektedir. Bununla birlikte, metabolik veya kardiyovasküler hastalarda HIIT'in BDNF üzerindeki etkisini açıklamak için daha fazla deneysel çalışmaya ihtiyaç duyulmaktadır. Yüksek egzersiz şiddetlerinin, etkili egzersiz programları oluşturmak için önemli bir faktör olabileceği ve HIIT programlarının özellikle sağlıklı bireylerde kardiovasküler fonksiyonun iyileştirilmesi için kritik bir öneme sahip olduğu söylenebilir. Sonuç olarak, güncel araştırmalar, özel popülasyonlarda uygulanan HIIT programlarının kardiyovasküler sağlık üzerinde olumlu etkilerini rapor etmesine rağmen, bu yöntemin egzersize fizyolojik adaptasyonu sağlamadaki etkinliğini belirlemek için daha fazla bilimsel araştırma sonuçlarına ihtiyaç duyulduğu ifade edilebilir.

Keywords

Yüksek şiddetli interval antrenmanı (HIIT), BDNF, Kardiyovasküler sağlık

References

1. Garber, C. E, Blissmer, B, Deschenes, M. R, Franklin, B. A, Lamonte, M. J, Lee, I. M. and Swain, D.P. (2011). “Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Healthy Adults”. Medicine & Science in Sports & Exercise, 43 (7), 1334–1359.
2. Jiménez-Maldonado, A, Rentería, I, García-Suárez, P.C, Moncada-Jiménez, J. and Freire-Royes, L.F. (2018). “The Impact of High-Intensity Interval Training on Brain Derived Neurotrophic Factor in Brain: A Mini-Review”. Frontiers in Neuroscience, 12.
3. Gibala, M. J, Little, J. P, MacDonald, M. J. and Hawley, J. A. (2012). “Physiological adaptations to low-volume, high-intensity interval training in health and disease”. The Journal of Physiology, 590(5), 1077-1084.
4. Issurin, V.B. (2010). “New Horizons for the Methodology and Physiology of Training Periodization”. Sports Medicine, 40(3), 189-206.
5. Frazão, D. T, de Farias Junior, L. F, Dantas, T. C. B, Krinski, K, Elsangedy, H.M, Prestes, J. and Costa, E.C. (2016). “Correction: Feeling of Pleasure to High-Intensity Interval Exercise is Dependent of the Number of Work Bouts and Physical Activity Status”. PLOS ONE, 11(4), e0153986.
6. Los Arcos, A, Vázquez, J. S, Martín, J, Lerga, J, Sánchez, F, Villagra, F. and Zulueta, J. J. (2015). “Effects of Small-Sided Games vs. Interval Training in Aerobic Fitness and Physical Enjoyment in Young Elite Soccer Players”. PLOS ONE, 10(9), e0137224.
7. Selmi, O, Haddad, M, Majed, L, Ben Khalifa, W, Hamza, M. and Chamari, K. (2018). “Soccer Training: High-İntensity İnterval Training is Mood Disturbing While Small Sided Games Ensure Mood Balance”. The Journal of Sports Medicine and Physical Fitness, 58 (7), 8.
8. Berger, B. G, Motl, R. W, Butki, B. D, Martin, D. T, Wilkinson, J. G. and Owen, D. R. (1999). “Mood and Cycling Performance in Response to Three Weeks of High-Intensity, Short-Duration Overtraining, and a Two-Week Taper”. The Sport Psychologist, 13(4), 444-457.
9. Cassilhas, R. C, Antunes, H. K. M, Tufik, S. and de Mello, M. T. (2010). “Mood, Anxiety, and Serum IGF-1 in Elderly Men Given 24 Weeks of High Resistance Exercise”. Perceptual and Motor Skills, 110 (1), 265-276.
10. Di Blasio, A, Izzicupo, P, Tacconi, L, Di Santo, S, Leogrande, M, Bucci, I. and Napolitano, G. (2016). “Acute and Delayed Effects of High İntensity Interval Resistance Training Organization on Cortisol and Testosterone Production”. The Journal of Sports Medicine and Physical Fitness, 56 (3), 192-199.
11. Meeusen, R, Duclos, M, Foster, C, Fry, A, Gleeson, M, Nieman, D. and Urhausen, A. (2013). “Prevention, Diagnosis And Treatment of The Overtraining Syndrome: Joint Consensus Statement of the European College of Sport Science (ECSS) and the American College of Sports Medicine (ACSM)”. European Journal of Sport Science, 13(1), 1–24.
12. Bishop, D. J, Botella, J, Genders, A. J, Lee, M. J. C, Saner, N. J, Kuang, J. and Granata, C. (2019). ‘‘High-Intensity Exercise and Mitochondrial Biogenesis: Current Controversies and Future Research Directions’’. Physiology, 34 (1), 56–70.
13. Metcalfe, R. S, Koumanov, F, Ruffino, J. S, Stokes, K. A, Holman, G. D, Thompson, D. and Vollaard, N. B. J. (2015). ‘‘Physiological and Molecular Responses to an Acute Bout of Reduced-Exertion High-İntensity İnterval Training (REHIT)’’. European Journal of Applied Physiology, 115 (11), 2321-2334.
14. Torma, F, Gombos, Z, Jokai, M, Takeda, M, Mimura, T. and Radak, Z. (2019). ‘‘High İntensity İnterval Training and Molecular Adaptive Response of Skeletal Muscle’’. Sports Medicine and Health Science, 1 (1), 24-32.
15. Little, J.P, Safdar, A, Wilkin, G.P, Tarnopolsky, M.A. and Gibala, M.J. (2010). ‘‘A Practical Model of Low-Volume High-İntensity İnterval Training İnduces Mitochondrial Biogenesis in Human Skeletal Muscle: Potential Mechanisms’’. The Journal of Physiology, 588 (6), 1011-1022.
16. Huang, T, Larsen, K.T, Ried-Larsen, M, Møller, N.C. and Andersen, L.B. (2014). ‘‘The Effects of Physical Activity and Exercise on Brain-Derived Neurotrophic Factor in Healthy Humans: A Review’’. Scandinavian Journal of Medicine & Science in Sports, 24 (1), 1-10.
17. Knaepen, K, Goekint, M, Heyman, E.M. and Meeusen, R. (2010). ‘‘Neuroplasticity-Exercise-Induced Response of Peripheral Brain-Derived Neurotrophic Factor’’. Sports Medicine, 40 (9), 765-801.
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Details

Primary Language	English
Subjects	Health Care Administration
Journal Section	Derlemeler
Authors	Serdar Bayrakdaroğlu 0000-0002-2166-6675 Nuri Topsakal 0000-0003-1583-107X Özgür Eken 0000-0002-5488-3158
Publication Date	March 19, 2022
Published in Issue	Year 2022 Volume: 11 Issue: 1

Cite

APA	Bayrakdaroğlu, S., Topsakal, N., & Eken, Ö. (2022). The Effects of High Intensive Interval Training (HIIT) on Brain-Derived Neurotrophic Factor (BDNF) and Cardiovascular Health: A Review. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi, 11(1), 346-354. https://doi.org/10.37989/gumussagbil.1052230
AMA	Bayrakdaroğlu S, Topsakal N, Eken Ö. The Effects of High Intensive Interval Training (HIIT) on Brain-Derived Neurotrophic Factor (BDNF) and Cardiovascular Health: A Review. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi. March 2022;11(1):346-354. doi:10.37989/gumussagbil.1052230
Chicago	Bayrakdaroğlu, Serdar, Nuri Topsakal, and Özgür Eken. “The Effects of High Intensive Interval Training (HIIT) on Brain-Derived Neurotrophic Factor (BDNF) and Cardiovascular Health: A Review”. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi 11, no. 1 (March 2022): 346-54. https://doi.org/10.37989/gumussagbil.1052230.
EndNote	Bayrakdaroğlu S, Topsakal N, Eken Ö (March 1, 2022) The Effects of High Intensive Interval Training (HIIT) on Brain-Derived Neurotrophic Factor (BDNF) and Cardiovascular Health: A Review. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi 11 1 346–354.
IEEE	S. Bayrakdaroğlu, N. Topsakal, and Ö. Eken, “The Effects of High Intensive Interval Training (HIIT) on Brain-Derived Neurotrophic Factor (BDNF) and Cardiovascular Health: A Review”, Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi, vol. 11, no. 1, pp. 346–354, 2022, doi: 10.37989/gumussagbil.1052230.
ISNAD	Bayrakdaroğlu, Serdar et al. “The Effects of High Intensive Interval Training (HIIT) on Brain-Derived Neurotrophic Factor (BDNF) and Cardiovascular Health: A Review”. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi 11/1 (March 2022), 346-354. https://doi.org/10.37989/gumussagbil.1052230.
JAMA	Bayrakdaroğlu S, Topsakal N, Eken Ö. The Effects of High Intensive Interval Training (HIIT) on Brain-Derived Neurotrophic Factor (BDNF) and Cardiovascular Health: A Review. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi. 2022;11:346–354.
MLA	Bayrakdaroğlu, Serdar et al. “The Effects of High Intensive Interval Training (HIIT) on Brain-Derived Neurotrophic Factor (BDNF) and Cardiovascular Health: A Review”. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi, vol. 11, no. 1, 2022, pp. 346-54, doi:10.37989/gumussagbil.1052230.
Vancouver	Bayrakdaroğlu S, Topsakal N, Eken Ö. The Effects of High Intensive Interval Training (HIIT) on Brain-Derived Neurotrophic Factor (BDNF) and Cardiovascular Health: A Review. Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi. 2022;11(1):346-54.

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