Cholesterol Adsorption from Artificial Human Plasma with Molecular Imprinted Polymeric Nanostructures

Abstract

This study reports cholesterol adsorption from artificial human plasma using MIP nanostructures prepared with different template:monomer ratios. The adsorption capacity of CP is 19.9% and 16.1% higher than those of C3P and CP3, respectively and adsorption capacity of CP is significantly higher than NIP nanostructures. All selectivity coefficients and relative selectivity values were higher than 1 for artificial human plasma. Under optimum conditions, considerably high cholesterol was adsorbed from hypercholesterolemic plasma (95.33 %). 

Keywords

• Cholesterol; molecular imprinting; plasma; nanostructures

References

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