Arylidene Carbazole Carbohydrazides: Synthesis and Characterization

Year 2018, Volume: 46 Issue: 2, 169 - 175, 03.06.2018

Cevher Gündoğdu Hızlıateş

Abstract

Because of the wide range of pharmacological activities and their distinctive structural features hydrazones
and carbazole alkaloids have attracted considerable attention in medicinal chemistry. In this study, new
carbazole acyl hydrozones (3a-k) which may have high biological activity potential, were synthesized with
condensation reaction between carbazole hydrazide and benzaldehyde derivatives. After determination of the
melting points of all synthesized derivatives, their structures were identified by FT-IR and 1
H-NMR spectroscopic
methods.

Keywords

Carbazole, carbohydrazide, hydrazide-hydrazone, biological activity

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