Cholesterol Adsorption from Artificial Human Plasma with Molecular Imprinted Polymeric Nanostructures

Year 2018, Volume: 46 Issue: 2, 285 - 296, 03.06.2018

Tülden İnanan Nalan Tüzmen

Abstract

This study reports cholesterol adsorption from artificial human plasma using MIP nanostructures prepared
with different template:monomer ratios. The adsorption capacity of CP is 19.9% and 16.1% higher than those
of C3P and CP3, respectively and adsorption capacity of CP is significantly higher than NIP nanostructures.
All selectivity coefficients and relative selectivity values were higher than 1 for artificial human plasma. Under
optimum conditions, considerably high cholesterol was adsorbed from hypercholesterolemic plasma (95.33 %). 

Keywords

Cholesterol; molecular imprinting; plasma; nanostructures

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