Research Article
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Year 2019, Volume: 47 Issue: 1, 23 - 32, 01.02.2019

Abstract

References

  • R.A. Burges, D.G. Gardiner, M. Gwilt, A.J. Higgins, K.J. Blackburn, S.F. Campbell, P.E. Cross, J.K. Stubbs, Calcium channel blocking properties of amlodipine in vascular smooth muscle and cardiac muscle in vitro: evidence for voltage modulation of vascular dihydropyridine receptors, J. Cardiovas. Pharm., 9 (1987) 110-9.
  • 2. A.A.K. Gazy, Determination of amlodipine besylate by adsorptive square-wave anodic stripping voltammetry on glassy carbon electrode in tablets and biological fluids, Talanta, 62 (2004) 575-582.
  • 3. T. Manuel, V. Velasquez, Angiotensin II receptor blockers: a new class of antihypertensive drugs, Arch. Fam. Med., 5 (1996) 351-356.
  • 4. H. Yi, W.H.-C. and S.B. Biointerfaces, undefined 2007, Enhancement effect of sodium dodecyl benzene sulfonate (SDBS) and its application into voltammetric determination of telmisartan, Elsevier. (n.d.).
  • 5. M.S. Kondawar, K.G. Kamble, K.S. Raut, K.H. Maharshi, UV Spectrophotometric estimation of Amlodipine besylate and Telmisartan in Bulk drug and Dosage form by Multiwavelength Analysis, Intern. J. Chem. Tech Res. 3 (n.d.) 974-4290.
  • 6. A.S. Arul, G. Dhas, A.K. Muthu, R. Sankhla, S. Gupta, A.A. Smith, R. Manavalan, Development and validation of a reversed phase hplc method for simultaneous determination of amlodipine and telmisartan in pharmaceutical dosage form, article in journal of chemical research, J. Appl. Chem. Res., 12 (2010) 43-52.
  • 7. A.R. Chabukswar, S.C. Jagdale, S. V Kumbhar, V.J. Kadam, V.D. Patil, B.S. Kuchekar, P.D. Lokhande, Simultaneous HPTLC estimation of telmisartan and amlodipine besylate in tablet dosage form, Arch. Appl. Sci. Res., 2 (2010) 94-100.
  • 8. S. Nalwade, V.R. Reddy, D.D. Rao, I.K. Rao, Rapid Simultaneous determination of telmisartan, amlodipine besylate and hydrochlorothiazide in a combined poly pill dosage form by stability-indicating ultra performance liquid chromatography, Scientia Pharmaceutica. 79 (2011) 69-84.
  • 9. R.N. Goyal, N. Bachheti, A. Tyagi, A.K. Pandey, Differential pulse voltammetric determination of methylprednisolone in pharmaceuticals and human biological fluids, Anal. Chim. Acta, 12 (2007) 34-40.
  • 10. N. Karadas-Bakirhan, M. Gumustas, B. Uslu, S.A. Ozkan, Simultaneous determination of amlodipine besylate and rosuvastatin calcium in binary mixtures by voltammetric and chromatographic techniques, Ionics, 22 (2016) 277-288.
  • 11. B.S. Goyal, Voltammetric determination of amlodipine besylate in human urine and pharmaceuticals, Bioelectrochem., 79 (2010) 234-240.
  • 12. B. Bozal-Palabiyik, B. Dogan-Topal, B. Uslu, A. Can, S.A. Ozkan, Sensitive voltammetric assay of etoposide using modified glassy carbon electrode with a dispersion of multiwalled carbon nanotube, J. Solid State Electrochem., 17 (2013) 2815-2822.
  • 13. S. Kurbanoglu, B. Dogan-Topal, B. Uslu, A. Can, S.A. Ozkan, Electrochemical investigations of the anticancer drug idarubicin using multiwalled carbon nanotubes modified glassy carbon and pyrolytic graphite electrodes, Electroanalysis, 25 (2013) 1473-1482.
  • 14. C. Brett, A. Brett, Electrochemistry: Principles, Methods, and Applications, Springer, (1993) 427.
  • 15. F. Agin, N. Karadas, B. Uslu, S.A. Ozkan, Electroanalytical characterization of levodropropizine and its voltammetric determination in pharmaceuticals, Curr. Pharm. Anal., 9 (2013).
  • 16. S.A. Ozkan, J.M. Kauffmann, P. Zuman, Electroanalysis in Biomedical and Pharmaceutical Sciences, Springer Berlin Heidelberg, Berlin, Heidelberg, 2015.
  • 17. N. Karadas, S. Sanli, M. Gumustas, S.A. Ozkan, Voltammetric and RP-LC assay for determination of benidipine HCl, J. Pharm. Biomed. Anal., 66 (2012).
  • 18. N. Karadas, S. Sanli, B. Akmese, B. Dogan-Topal, A. Can, S.A. Ozkan, Analytical application of polymethylene bluemultiwalled carbon nanotubes modified glassy carbon electrode on anticancer drug irinotecan and determination of its ionization constant value, Talanta, 115 (2013) 911-919.
  • 19. N. Karadas, S.A. Ozkan, Electrochemical preparation of sodium dodecyl sulfate doped over-oxidized polypyrrole/ multi-walled carbon nanotube composite on glassy carbon electrode and its application on sensitive and selective determination of anticancer drug: Pemetrexed, Talanta, 119 (2014).
  • 20. S.A. Ozkan, Electroanalytical Methods in Pharmaceutical Analysis and Their Validation, First edit, HNB Pub., 2012.
  • 21. M. Gumustas, N. Karadas, S.A. Ozkan, Validated electroanalytical and RP-LC assay of ertapenem in its pharmaceutical dosage form, Rev. Roum. Chim., 58 (2013) 679-690

Electroanalytical Studies and Simultaneous Validated Assay of Antihypertensive Compounds in Their Binary Mixtures Using Fast Electrochemical Technique

Year 2019, Volume: 47 Issue: 1, 23 - 32, 01.02.2019

Abstract

The electrochemical behavior of amlodipine (AML) and telmisartan (TLM) on a glassy carbon electrode were investigated in different aqueous solutions by using cyclic, differential pulse, and square wave voltammetric techniques. AML and TLM exhibited one peak (both of them) to the anodic direction. The oxidation process was found to be irreversible and adsorption controlled. To obtain good sensitivity, the instrumental and accumulation variables were studied using square wave voltammetry (SWV) techniques in 0.5 M H2SO4 solution, which was obtained as the most repeatabile and sensitive media. In this study; sensitive, fast and reliable method development was aimed for simultaneous detection of AML and TLM. This voltammetric method exhibited linear dynamic responses in the concentration range between 1.0×10-7 M and 1.0×10-4 M for AML and 1.0×10-7 M and 1.0×10-5 M for TLM, with detection limits of 0.654 nM and 22.6 nM, respectively. The proposed method is validated and successfully applied for the analysis of AML and TLM tablets.

References

  • R.A. Burges, D.G. Gardiner, M. Gwilt, A.J. Higgins, K.J. Blackburn, S.F. Campbell, P.E. Cross, J.K. Stubbs, Calcium channel blocking properties of amlodipine in vascular smooth muscle and cardiac muscle in vitro: evidence for voltage modulation of vascular dihydropyridine receptors, J. Cardiovas. Pharm., 9 (1987) 110-9.
  • 2. A.A.K. Gazy, Determination of amlodipine besylate by adsorptive square-wave anodic stripping voltammetry on glassy carbon electrode in tablets and biological fluids, Talanta, 62 (2004) 575-582.
  • 3. T. Manuel, V. Velasquez, Angiotensin II receptor blockers: a new class of antihypertensive drugs, Arch. Fam. Med., 5 (1996) 351-356.
  • 4. H. Yi, W.H.-C. and S.B. Biointerfaces, undefined 2007, Enhancement effect of sodium dodecyl benzene sulfonate (SDBS) and its application into voltammetric determination of telmisartan, Elsevier. (n.d.).
  • 5. M.S. Kondawar, K.G. Kamble, K.S. Raut, K.H. Maharshi, UV Spectrophotometric estimation of Amlodipine besylate and Telmisartan in Bulk drug and Dosage form by Multiwavelength Analysis, Intern. J. Chem. Tech Res. 3 (n.d.) 974-4290.
  • 6. A.S. Arul, G. Dhas, A.K. Muthu, R. Sankhla, S. Gupta, A.A. Smith, R. Manavalan, Development and validation of a reversed phase hplc method for simultaneous determination of amlodipine and telmisartan in pharmaceutical dosage form, article in journal of chemical research, J. Appl. Chem. Res., 12 (2010) 43-52.
  • 7. A.R. Chabukswar, S.C. Jagdale, S. V Kumbhar, V.J. Kadam, V.D. Patil, B.S. Kuchekar, P.D. Lokhande, Simultaneous HPTLC estimation of telmisartan and amlodipine besylate in tablet dosage form, Arch. Appl. Sci. Res., 2 (2010) 94-100.
  • 8. S. Nalwade, V.R. Reddy, D.D. Rao, I.K. Rao, Rapid Simultaneous determination of telmisartan, amlodipine besylate and hydrochlorothiazide in a combined poly pill dosage form by stability-indicating ultra performance liquid chromatography, Scientia Pharmaceutica. 79 (2011) 69-84.
  • 9. R.N. Goyal, N. Bachheti, A. Tyagi, A.K. Pandey, Differential pulse voltammetric determination of methylprednisolone in pharmaceuticals and human biological fluids, Anal. Chim. Acta, 12 (2007) 34-40.
  • 10. N. Karadas-Bakirhan, M. Gumustas, B. Uslu, S.A. Ozkan, Simultaneous determination of amlodipine besylate and rosuvastatin calcium in binary mixtures by voltammetric and chromatographic techniques, Ionics, 22 (2016) 277-288.
  • 11. B.S. Goyal, Voltammetric determination of amlodipine besylate in human urine and pharmaceuticals, Bioelectrochem., 79 (2010) 234-240.
  • 12. B. Bozal-Palabiyik, B. Dogan-Topal, B. Uslu, A. Can, S.A. Ozkan, Sensitive voltammetric assay of etoposide using modified glassy carbon electrode with a dispersion of multiwalled carbon nanotube, J. Solid State Electrochem., 17 (2013) 2815-2822.
  • 13. S. Kurbanoglu, B. Dogan-Topal, B. Uslu, A. Can, S.A. Ozkan, Electrochemical investigations of the anticancer drug idarubicin using multiwalled carbon nanotubes modified glassy carbon and pyrolytic graphite electrodes, Electroanalysis, 25 (2013) 1473-1482.
  • 14. C. Brett, A. Brett, Electrochemistry: Principles, Methods, and Applications, Springer, (1993) 427.
  • 15. F. Agin, N. Karadas, B. Uslu, S.A. Ozkan, Electroanalytical characterization of levodropropizine and its voltammetric determination in pharmaceuticals, Curr. Pharm. Anal., 9 (2013).
  • 16. S.A. Ozkan, J.M. Kauffmann, P. Zuman, Electroanalysis in Biomedical and Pharmaceutical Sciences, Springer Berlin Heidelberg, Berlin, Heidelberg, 2015.
  • 17. N. Karadas, S. Sanli, M. Gumustas, S.A. Ozkan, Voltammetric and RP-LC assay for determination of benidipine HCl, J. Pharm. Biomed. Anal., 66 (2012).
  • 18. N. Karadas, S. Sanli, B. Akmese, B. Dogan-Topal, A. Can, S.A. Ozkan, Analytical application of polymethylene bluemultiwalled carbon nanotubes modified glassy carbon electrode on anticancer drug irinotecan and determination of its ionization constant value, Talanta, 115 (2013) 911-919.
  • 19. N. Karadas, S.A. Ozkan, Electrochemical preparation of sodium dodecyl sulfate doped over-oxidized polypyrrole/ multi-walled carbon nanotube composite on glassy carbon electrode and its application on sensitive and selective determination of anticancer drug: Pemetrexed, Talanta, 119 (2014).
  • 20. S.A. Ozkan, Electroanalytical Methods in Pharmaceutical Analysis and Their Validation, First edit, HNB Pub., 2012.
  • 21. M. Gumustas, N. Karadas, S.A. Ozkan, Validated electroanalytical and RP-LC assay of ertapenem in its pharmaceutical dosage form, Rev. Roum. Chim., 58 (2013) 679-690
There are 21 citations in total.

Details

Primary Language English
Journal Section Articles
Authors

Nurgul K. Bakirhan

Fatma Kartal This is me

Sibel A. Özkan This is me

Publication Date February 1, 2019
Acceptance Date December 7, 2018
Published in Issue Year 2019 Volume: 47 Issue: 1

Cite

APA Bakirhan, N. K., Kartal, F., & Özkan, S. A. (2019). Electroanalytical Studies and Simultaneous Validated Assay of Antihypertensive Compounds in Their Binary Mixtures Using Fast Electrochemical Technique. Hacettepe Journal of Biology and Chemistry, 47(1), 23-32.
AMA Bakirhan NK, Kartal F, Özkan SA. Electroanalytical Studies and Simultaneous Validated Assay of Antihypertensive Compounds in Their Binary Mixtures Using Fast Electrochemical Technique. HJBC. February 2019;47(1):23-32.
Chicago Bakirhan, Nurgul K., Fatma Kartal, and Sibel A. Özkan. “Electroanalytical Studies and Simultaneous Validated Assay of Antihypertensive Compounds in Their Binary Mixtures Using Fast Electrochemical Technique”. Hacettepe Journal of Biology and Chemistry 47, no. 1 (February 2019): 23-32.
EndNote Bakirhan NK, Kartal F, Özkan SA (February 1, 2019) Electroanalytical Studies and Simultaneous Validated Assay of Antihypertensive Compounds in Their Binary Mixtures Using Fast Electrochemical Technique. Hacettepe Journal of Biology and Chemistry 47 1 23–32.
IEEE N. K. Bakirhan, F. Kartal, and S. A. Özkan, “Electroanalytical Studies and Simultaneous Validated Assay of Antihypertensive Compounds in Their Binary Mixtures Using Fast Electrochemical Technique”, HJBC, vol. 47, no. 1, pp. 23–32, 2019.
ISNAD Bakirhan, Nurgul K. et al. “Electroanalytical Studies and Simultaneous Validated Assay of Antihypertensive Compounds in Their Binary Mixtures Using Fast Electrochemical Technique”. Hacettepe Journal of Biology and Chemistry 47/1 (February 2019), 23-32.
JAMA Bakirhan NK, Kartal F, Özkan SA. Electroanalytical Studies and Simultaneous Validated Assay of Antihypertensive Compounds in Their Binary Mixtures Using Fast Electrochemical Technique. HJBC. 2019;47:23–32.
MLA Bakirhan, Nurgul K. et al. “Electroanalytical Studies and Simultaneous Validated Assay of Antihypertensive Compounds in Their Binary Mixtures Using Fast Electrochemical Technique”. Hacettepe Journal of Biology and Chemistry, vol. 47, no. 1, 2019, pp. 23-32.
Vancouver Bakirhan NK, Kartal F, Özkan SA. Electroanalytical Studies and Simultaneous Validated Assay of Antihypertensive Compounds in Their Binary Mixtures Using Fast Electrochemical Technique. HJBC. 2019;47(1):23-32.

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