Practical synthesis of pyrido[1,2-a]benzimidazoles via multicomponent reactions

Year 2019, Volume: 47 Issue: 4, 435 - 442, 01.12.2019

Akın Sağırlı

https://doi.org/10.15671/hjbc.550890

Cited By: 2

Abstract

Tek basamakta siklik enamin (2-(nitrometilen)-2,3-dihidro-1H-benzo[d]imidazol),
malononitril ve aromatik aldehit ile çoklu bileşenli tepkime üzerinden 1-amino-3-(4-substitue)-4-nitro-3,5-dihidrobenzo[4,5]imidazo[1,2-a]piridin-2-karbonitril
lerin kolay ve etkili bir biçimde sentezi açığa çıkarıldı. Ayrıca, istenilen
ürünlerin eldesinde herhangi bir saflaştırma prosedürü gerektirmedi. Bütün
ürünler saf olarak tepkime ortamında çökeltildi. On yeni yapı fiziksel ve
spektroskopik yöntemler kullanılarak karakterize edildi (e.n., IR, NMR ve
TOF-MS analizleri).

Keywords

Heterocyclic ketene aminal, enamine, multicomponent, benzimidazole, pyridobenzimidazole

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