Review
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Micro and Nanogels for Biomedical Applications

Year 2020, The 100 Year of Polymers, 407 - 424, 01.11.2020

Mehmet Can Olgun Guven Nurettin Sahiner

https://doi.org/10.15671/hjbc.810599
Cited By: 4

Abstract

Micro and nano hydrogels developed from natural and synthetic polymers have garnered great deal of attention in scientific and industrial realms due to their higher surface area, degree of swelling and active material loading capacity, softness and flexibility, as well as their similarity to natural tissues. Particularly, biocompatible, non-toxic, and biodegradable micro/nano vehicles with tailor made design and functionalization facilities their use with excellent feasibility for a variety of biomedical applications such as tissue engineering, bioimaging and drug delivery. However, these platforms require rational design and functionalization strategies to cope with barriers of in vivo environment to pass into clinical use. Firstly, an ideal carrier should be biocompatible, and capable of evasion from immune elimination, specifically target at desired sites and sustainably release the therapeutic cargo in response to microenvironment conditions. Despite the few setbacks in micro/nano vehicle design and several successful formulations translated to clinical use and majority of the carries are yet to achieve complete success for all biological criteria. In this review, design, and functionalization strategies of micro and nanogels have been summarized and the recent progress in biomedical applications of microgels and nanogels have been outlined with a primary focus placed on drug and biomolecule delivery applications.

Keywords

microgel nanogel drug delivery biomedical applications.

Supporting Institution

N/A

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Year 2020, The 100 Year of Polymers, 407 - 424, 01.11.2020

Mehmet Can Olgun Guven Nurettin Sahiner

https://doi.org/10.15671/hjbc.810599
Cited By: 4

Abstract

References

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There are 148 citations in total.

Details

Primary Language English
Subjects Engineering
Journal Section Articles
Authors

Mehmet Can This is me 0000-0002-5993-206X

Olgun Guven This is me 0000-0002-7559-1365

Nurettin Sahiner 0000-0003-0120-530X

Publication Date November 1, 2020
Acceptance Date October 16, 2020
Published in Issue Year 2020 The 100 Year of Polymers

Cite

APA Can, M., Guven, O., & Sahiner, N. (2020). Micro and Nanogels for Biomedical Applications. Hacettepe Journal of Biology and Chemistry, 48(5), 407-424. https://doi.org/10.15671/hjbc.810599
AMA Can M, Guven O, Sahiner N. Micro and Nanogels for Biomedical Applications. HJBC. November 2020;48(5):407-424. doi:10.15671/hjbc.810599
Chicago Can, Mehmet, Olgun Guven, and Nurettin Sahiner. “Micro and Nanogels for Biomedical Applications”. Hacettepe Journal of Biology and Chemistry 48, no. 5 (November 2020): 407-24. https://doi.org/10.15671/hjbc.810599.
EndNote Can M, Guven O, Sahiner N (November 1, 2020) Micro and Nanogels for Biomedical Applications. Hacettepe Journal of Biology and Chemistry 48 5 407–424.
IEEE M. Can, O. Guven, and N. Sahiner, “Micro and Nanogels for Biomedical Applications”, HJBC, vol. 48, no. 5, pp. 407–424, 2020, doi: 10.15671/hjbc.810599.
ISNAD Can, Mehmet et al. “Micro and Nanogels for Biomedical Applications”. Hacettepe Journal of Biology and Chemistry 48/5 (November 2020), 407-424. https://doi.org/10.15671/hjbc.810599.
JAMA Can M, Guven O, Sahiner N. Micro and Nanogels for Biomedical Applications. HJBC. 2020;48:407–424.
MLA Can, Mehmet et al. “Micro and Nanogels for Biomedical Applications”. Hacettepe Journal of Biology and Chemistry, vol. 48, no. 5, 2020, pp. 407-24, doi:10.15671/hjbc.810599.
Vancouver Can M, Guven O, Sahiner N. Micro and Nanogels for Biomedical Applications. HJBC. 2020;48(5):407-24.

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