Injectable Polyethylene Glycol Terminated Poly propylene fumarate / Acrylamide Biodegradable Materials for Cardiac Applications

Bobby C. Kallukalam; Mutu Jayabalan; Vandana Sankar

Injectable Polyethylene Glycol Terminated Poly propylene fumarate / Acrylamide Biodegradable Materials for Cardiac Applications

Year 2008, Volume: 36 Issue: 4, 283 - 290, 01.12.2008

Bobby C. Kallukalam Mutu Jayabalan Vandana Sankar

Abstract

Injectable and biodegradable hydrogel material based on polyethylene glycol terminated poly propylenefumarate PEG-PPF-PEG / acrylamide have been developed and evaluated for cardiac applications. The presentPEG-PPF-PEG resin undergoes fast setting with acrylamide with low exothermic temperature and mechanicalproperties equivalent to that of cardiac tissue. The chemically cross linked hydrogels undergo swelling in Ringer’ssolution prior to degradation. The present material are non cytotoxic to L-929 fibroblast and compatible with thecardiac fibroblast cells. Adhesion and proliferation of cardiac fibroblast cells has been appreciably good which is dueto surface reorganisation and generation of synergistic hydrophilic-hydrophobic surface

Keywords

Injectable and biodegradable hydrogel, Polyethylene glycol terminated pol propylene fumarate /acrylamide, Fast

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There are 13 citations in total.

Details

Primary Language	English
Journal Section	Research Article
Authors	Bobby C. Kallukalam This is me Mutu Jayabalan This is me Vandana Sankar This is me
Publication Date	December 1, 2008
Published in Issue	Year 2008 Volume: 36 Issue: 4

Cite

APA	Kallukalam, B. C., Jayabalan, M., & Sankar, V. (2008). Injectable Polyethylene Glycol Terminated Poly propylene fumarate / Acrylamide Biodegradable Materials for Cardiac Applications. Hacettepe Journal of Biology and Chemistry, 36(4), 283-290.
AMA	Kallukalam BC, Jayabalan M, Sankar V. Injectable Polyethylene Glycol Terminated Poly propylene fumarate / Acrylamide Biodegradable Materials for Cardiac Applications. HJBC. December 2008;36(4):283-290.
Chicago	Kallukalam, Bobby C., Mutu Jayabalan, and Vandana Sankar. “Injectable Polyethylene Glycol Terminated Poly Propylene Fumarate / Acrylamide Biodegradable Materials for Cardiac Applications”. Hacettepe Journal of Biology and Chemistry 36, no. 4 (December 2008): 283-90.
EndNote	Kallukalam BC, Jayabalan M, Sankar V (December 1, 2008) Injectable Polyethylene Glycol Terminated Poly propylene fumarate / Acrylamide Biodegradable Materials for Cardiac Applications. Hacettepe Journal of Biology and Chemistry 36 4 283–290.
IEEE	B. C. Kallukalam, M. Jayabalan, and V. Sankar, “Injectable Polyethylene Glycol Terminated Poly propylene fumarate / Acrylamide Biodegradable Materials for Cardiac Applications”, HJBC, vol. 36, no. 4, pp. 283–290, 2008.
ISNAD	Kallukalam, Bobby C. et al. “Injectable Polyethylene Glycol Terminated Poly Propylene Fumarate / Acrylamide Biodegradable Materials for Cardiac Applications”. Hacettepe Journal of Biology and Chemistry 36/4 (December 2008), 283-290.
JAMA	Kallukalam BC, Jayabalan M, Sankar V. Injectable Polyethylene Glycol Terminated Poly propylene fumarate / Acrylamide Biodegradable Materials for Cardiac Applications. HJBC. 2008;36:283–290.
MLA	Kallukalam, Bobby C. et al. “Injectable Polyethylene Glycol Terminated Poly Propylene Fumarate / Acrylamide Biodegradable Materials for Cardiac Applications”. Hacettepe Journal of Biology and Chemistry, vol. 36, no. 4, 2008, pp. 283-90.
Vancouver	Kallukalam BC, Jayabalan M, Sankar V. Injectable Polyethylene Glycol Terminated Poly propylene fumarate / Acrylamide Biodegradable Materials for Cardiac Applications. HJBC. 2008;36(4):283-90.