The Phenolic Compounds from Hypericum Perforatum and Their Antimicrobial Activities

Year 2008, Volume: 36 Issue: 4, 339 - 345, 01.12.2008

Gönül Çelen Semiha Özkan Fatma Ayhan

Abstract

Hypericum perforatum St. John’s wort H. perforatum is a plant which has been used as a medicinal herb sinceancient times and grow in Europe, West Asia and North Africa. In this work, the crude extracts of HypericumPerforatum grown in Muğla were obtained by the extraction with acetone:water and water. The extracts werechemically investigated for their total phenol contents by the Folin–Ciocalteu method. The phenolic compounds in theextract with acetone:water 7:3, v/v, 150.44 mg GA/g material was determined as almost five fold higher than waterextraction process 33.01 mg GA/g material . The thin layer chromatographic TLC analysis revealed the presenceof polyphenolic compounds such as tannins

Keywords

Hypericum perforatum, Tannins, Total phenol content, TLC, antimicrobial activity, Muğla

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