Preparation and Properties of Electrospun Poly vinyl alcohol Blended Hybrid Polymer with Aloe vera and HPMC as Wound Dressing

Year 2010, Volume: 38 Issue: 1, 19 - 25, 01.01.2010

İbrahim Uslu Selda Keskin Ali Gül Tutku Ceren Karabulut Mehmet Levent Aksu

Abstract

A series of poly vinyl alcohol PVA /poly vinyl pyrrolidone PVP /poly ethylene glycol PEG hybrid nanofibers were fabricated by an electrospinning method, in order to be used as a potential wound dressing material. The effect of Aloe vera was investigated in terms of solution properties such as viscosity, conductivity, pH and surface tension. The nanofibrous wound dressing materials were characterized by scanning electron microscopy SEM , Fourier transform infrared FT-IR and differential scanning calorimetry DSC . SEM results revealed that the fiber diameters ranged between 200-500 nm and they were linear, homogenous and free of beads. DSC thermograms indicated that the addition of Aloe vera affects the crystal structure and efficiently cross-links the hybrid polymer, forming an amorphous structure with a melting temperature Tm of 219oC at an Aloe vera concentration of 3%. FTIR results clearly resolved the hybrid polymer structure of nanofibers obtained.

Keywords

Nanofiber, Electrospun, PVA, PEG, PVP, wound dressing, Aloe vera

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