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Pediatrik Yaş Grubunda Trombosit İndisleri

Year 2011, Volume: 39 Issue: 1, 83 - 86, 01.01.2011

Abstract

Trombosit indisleri olan ortalama trombosit hacmi, trombosit hematokriti ve trombosit genişlik dağılımı, klinisyenler tarafından çok da dikkate alınmayan parametrelerdir. Her ne kadar bazı hastalıklarla ilişkileri belirtilmişse de, henüz tam bir tanı değeri bulunmamaktadır. Amacımız, trombosit parametrelerini 6 ay-18 yaş arası çocukluk çağı yaş grubunda dağılımlarını belirlemektir. Elde ettiğimiz veriler, trombosit sayısının artmasıyla, trombosit hematokrit değerinin arttığını r = 0.91, p < 0.0001 ve buna karşın ortalama trombosit hacmiyle ters orantılı olduğunu göstermiştir r = 0.3, p < 0.001 . Trombosit genişlik dağılımı ortalama trombosit hacmi arasında doğru orantılı bir bağıntı varken r = 0.3, p < 0.001 , trombosit sayısı r= -0.2 ve trombosit hematokriti r = -0.1 ile arasında ters bir orantı bulunmaktadır r = -0.1, p < 0.001 . Verilerimiz trombosit dağılım genişliğinin temel olduğunu ve bazı hastalıklarda tanı ve ayırıcı tanıda kullanılabileceğini düşündürmektedir

References

  • [1] M.G. Farias, E.G. Schunck, S. Dal Bo, S.M. de Castro, Definition of reference ranges for the platelet distribution width (PDW): a local need, Clin. Chem. Lab. Med., 48 (2010) 255.
  • [2] J.C. Osselaer, J. Jamart, J.M. Scheiff, Platelet distribution width for differential diagnosis of thrombocytosis, Clin. Chem., 43 (1997) 1072.
  • [3] K.M. Bowles, L.J. Cooke, E.M. Richards, T.P. Baglin, Platelet size has diagnostic predictive value in patients with thrombocytopenia, Clin. Lab. Haematol., 27 (2005) 370.
  • [4] A. Wasiluk, J. Osada, M. Dabrowska, M. Szczepaski, E. Jasinska, Does prematurity affect platelet indices? Adv. Med. Sci., 54 (2009) 253.
  • [5] M.C. Becerra-Flores, J.M. Farfan-Canto, B. NievaGarcia, A. Fajardo-Gutierrez, Platelet reference values in healthy children living in Mexico City, Rev. Med. Inst. Mex. Seguro. Soc., 44 (2006) 121.
  • [6] C.H. Patrick, J. Lazarchick, T. Stubbs, W.B. Pittard, Mean platelet volume and platelet distribution width in the neonate. Am. J. Pediatr. Hematol. Oncol., 9 (1987) 130.
  • [7] A. Muscari, S. De Pascalis, A. Cenni, C. Ludovico, N. Castaldini, S. Antonelli, G. Bianchi, D. Magalotti, M. Zoli, Determinants of mean platelet volume (MPV) in an elderly population: relevance of body fat, blood glucose and ischaemic electrocardiographic changes, Thromb. Haemost., 99 (2008) 1079.
  • [8] L. Ruocco, L. Del Corso, A.M. Romanelli, D. Deri, F. Pentimone, New hematological indices in the healthy elderly. Minerva Med., 92 (2001) 69.
  • [10] M.A. Amin, A.P. Amin, H.R. Kulkarni, Platelet distribution width (PDW) is increased in vasoocclusive crisis in sickle cell disease. Ann. Hematol., 83 (2004) 331.
  • [11] P.C. Bartels, M. Schoorl, A.J. Lombarts, Screening for EDTA-dependent deviations in platelet counts and abnormalities in platelet distribution histograms in pseudothrombocytopenia. Scand. J. Clin. Lab. Invest., 57 (1997) 629.

Thrombocyte Indices in Pediatric Age Group

Year 2011, Volume: 39 Issue: 1, 83 - 86, 01.01.2011

Abstract

Platelet PLT indices mean platelet volume MPV , platelet hematocrit PCT and platelet distribution width PDW are probably the most ignored parameters by the clinicians. Although several studies held among different disease states, they do not have diagnostic value yet. Our aim was to determine the reference range of platelet parameters in venous blood samples of a population with an age range 6 months to 18 years in a hospital laboratory. This retrospective study consisted of 710 healthy children and the subjects were categorized into five groups according to their age. Age distribution of these groups was 6 months; 12 months; 18 months; 2-5 years and 6-18 years respectively. Our data revealed significant differences with regard to the MPV, PCT and PDW among the groups p

References

  • [1] M.G. Farias, E.G. Schunck, S. Dal Bo, S.M. de Castro, Definition of reference ranges for the platelet distribution width (PDW): a local need, Clin. Chem. Lab. Med., 48 (2010) 255.
  • [2] J.C. Osselaer, J. Jamart, J.M. Scheiff, Platelet distribution width for differential diagnosis of thrombocytosis, Clin. Chem., 43 (1997) 1072.
  • [3] K.M. Bowles, L.J. Cooke, E.M. Richards, T.P. Baglin, Platelet size has diagnostic predictive value in patients with thrombocytopenia, Clin. Lab. Haematol., 27 (2005) 370.
  • [4] A. Wasiluk, J. Osada, M. Dabrowska, M. Szczepaski, E. Jasinska, Does prematurity affect platelet indices? Adv. Med. Sci., 54 (2009) 253.
  • [5] M.C. Becerra-Flores, J.M. Farfan-Canto, B. NievaGarcia, A. Fajardo-Gutierrez, Platelet reference values in healthy children living in Mexico City, Rev. Med. Inst. Mex. Seguro. Soc., 44 (2006) 121.
  • [6] C.H. Patrick, J. Lazarchick, T. Stubbs, W.B. Pittard, Mean platelet volume and platelet distribution width in the neonate. Am. J. Pediatr. Hematol. Oncol., 9 (1987) 130.
  • [7] A. Muscari, S. De Pascalis, A. Cenni, C. Ludovico, N. Castaldini, S. Antonelli, G. Bianchi, D. Magalotti, M. Zoli, Determinants of mean platelet volume (MPV) in an elderly population: relevance of body fat, blood glucose and ischaemic electrocardiographic changes, Thromb. Haemost., 99 (2008) 1079.
  • [8] L. Ruocco, L. Del Corso, A.M. Romanelli, D. Deri, F. Pentimone, New hematological indices in the healthy elderly. Minerva Med., 92 (2001) 69.
  • [10] M.A. Amin, A.P. Amin, H.R. Kulkarni, Platelet distribution width (PDW) is increased in vasoocclusive crisis in sickle cell disease. Ann. Hematol., 83 (2004) 331.
  • [11] P.C. Bartels, M. Schoorl, A.J. Lombarts, Screening for EDTA-dependent deviations in platelet counts and abnormalities in platelet distribution histograms in pseudothrombocytopenia. Scand. J. Clin. Lab. Invest., 57 (1997) 629.
There are 10 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Abbas Yousefi Rad This is me

Şükrü Cin This is me

Nejat Akar This is me

Publication Date January 1, 2011
Published in Issue Year 2011 Volume: 39 Issue: 1

Cite

APA Rad, A. Y., Cin, Ş., & Akar, N. (2011). Pediatrik Yaş Grubunda Trombosit İndisleri. Hacettepe Journal of Biology and Chemistry, 39(1), 83-86.
AMA Rad AY, Cin Ş, Akar N. Pediatrik Yaş Grubunda Trombosit İndisleri. HJBC. January 2011;39(1):83-86.
Chicago Rad, Abbas Yousefi, Şükrü Cin, and Nejat Akar. “Pediatrik Yaş Grubunda Trombosit İndisleri”. Hacettepe Journal of Biology and Chemistry 39, no. 1 (January 2011): 83-86.
EndNote Rad AY, Cin Ş, Akar N (January 1, 2011) Pediatrik Yaş Grubunda Trombosit İndisleri. Hacettepe Journal of Biology and Chemistry 39 1 83–86.
IEEE A. Y. Rad, Ş. Cin, and N. Akar, “Pediatrik Yaş Grubunda Trombosit İndisleri”, HJBC, vol. 39, no. 1, pp. 83–86, 2011.
ISNAD Rad, Abbas Yousefi et al. “Pediatrik Yaş Grubunda Trombosit İndisleri”. Hacettepe Journal of Biology and Chemistry 39/1 (January 2011), 83-86.
JAMA Rad AY, Cin Ş, Akar N. Pediatrik Yaş Grubunda Trombosit İndisleri. HJBC. 2011;39:83–86.
MLA Rad, Abbas Yousefi et al. “Pediatrik Yaş Grubunda Trombosit İndisleri”. Hacettepe Journal of Biology and Chemistry, vol. 39, no. 1, 2011, pp. 83-86.
Vancouver Rad AY, Cin Ş, Akar N. Pediatrik Yaş Grubunda Trombosit İndisleri. HJBC. 2011;39(1):83-6.

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