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The Chemical Analysis of Propolis, Which are Produced in Western of Turkey

Year 2016, Volume: 44 Issue: 3, 327 - 338, 01.09.2016

Abstract

Propolis or bee glue is a natural product that contains numerous fairly strong chemical compounds and it is important for people health. But propolis collecting area and collecting time are very important for the product quality. For this purpose, this study conducted in the region of Muğla city in western of Turkey and propolis features uncovered. 27 propolis samples were collected from nine areas of the Muğla city in western of Turkey where honeydew beekeeping is practiced extensively, from September to November. GC-MS chemical substance analyses of 27 propolis samples revealed many chemicals including alcohols, aromatic alcohols, linear aldehydes, flavanones, linear hydrocarbons, linear acid esters, aromatic acids, aromatic esters, aromatic acid esters, aliphatic carboxilic acids, aliphatic carboxilic acid esters, aliphatic esters and other chemical substances. Propolis concentration changed between 0.71% and 13%. according to the amount of propolis used.

References

  • V.D. Wagh, Propolis: a wonder bees product and its pharmacological potentials, Adv. Pharm. Sci., 2013 (2013) 308249.
  • V. Bankova, M. Popova, S. Bogdanov, A.G. Sabatini, Chemical composition of European propolis: expected and unexpected results. Z Naturforsch., 57 (2002) 530-533.
  • S. Castaldo, F. Capasso, Propolis, an old remedy used in modern medicine. Fitoterapia, 73 (2002) 1–6.
  • L. Monzote, O. Cuesta-Rubio, M. Campo Fernandez, I. Márquez Hernandez, J. Fraga, K. Pérez, M. Kerstens, L. Maes, P. Cos, In vitro antimicrobial assessment of Cuban propolis extracts. Mem. Inst. Oswaldo Cruz, 107 (2012) 978-984.
  • H. Shi, H. Yang, X. Zhang, L. Yu, Identification and quantification of phytochemical composition and anti-inflammatory and radical scavenging properties of methanolic extracts of Chinese propolis. J. Agr. Food Chem., 60 (2012) 12403-12410.
  • G.C. Chan, K.W Cheung, D.M. Sze, The immunomodulatory and anticancer properties of propolis. Clin. Rev. Allergy Immunol., 44 (2013) 262- 273.
  • M.I. Nieva Moreno, M.I. Isla, N.G. Cudmani, M.A. Vattuone, A. R. Sampietro, Screening of antibacterial activity of Amaicha del Valle (Tucumán, Argentina) própolis . Ethnopharmacol, 68 (1999) 97–102.
  • O. Koru, F. Toskay, C.H. Açıkel, Y.M. Tunca, M. Baysallar, G.A. Üsküdar, E. Akça, A. Özkök Tüylü, K. Sorkun, M. Tanyüksel, B. Salih, In vitro antimicrobial activity of propolis samples from different geographical origins against certain oral pathogens, Anaerobe, 13,3-4 (2007) 140-145.
  • N. Vera, E. Solorzano, R. Ordóñez, L. Maldonado, E. Bedascarrasbure, M.I. Isla Chemical composition of Argentinean propolis collected in extreme regions and its relation with antimicrobial and antioxidant activities, Nat Prod. Commun., 6 (2011) 823–827.
  • E. Solorzano, N. Vera, S. Cuello, R. Ordóñez, C. Zampini, L. Maldonado, E. Bedascarrasbure, M.I. Isla Chalcones in bioactive argentine propolis collected in arid environments Nat. Prod. Commun., 7 (2012) 879–882.
  • A.L. Salas, R.M. Ordóñez, C. Silva, L. Maldonado, E. Bedascarrasbure, M.I. Isla, I.C. Zampini, Antimicrobial activity of Argentinean propolis against Staphylococcus isolated of canine otitis J. Exp. Biol. Agric. Sci., 2 (2014) 197–207.
  • M.B. Agüero, M. González, B. Lima, L. Svetaz, M. Sánchez, S. Zacchino, G. Feresin, G. Schmeda- Hirschmann, J. Palermo, D. Wunderlin, A. Tapia Argentinean propolis from Zuccagnia punctata Cav. (Caesalpiniceae) exudates: phytochemical characterization and antifungal activity J. Agric. Food Chem., 58 (2010) 194–201.
  • M.I. Isla, M.I. Nieva Moreno, C. Zampini, E. Solórzano, C. Danert, A. Salas, N. Vera, J. Sayago, E. Bedascarrasbure, L. Maldonado, R. Ordóñez Argentine propolis: flavonoid and chalcone content and its relation with the functional properties T. Farroqui, A.A. Farooqui (Eds.), Beneficial Effects of Propolis on Human Health and Chronic Diseases, Nova Science Publishers, Hauppauge (New York) (2013) 161–170.
  • M.I. Nieva Moreno, I.C. Zampini, M. Ordóñez, M.A. Vattuone, M.I. Isla Evaluation of the cytotoxicity, mutagenicity and antimutagenicity of propolis from Amaicha del Valle, Tucumán, Argentina J. Agric. Food Chem., 53 (2005) 8957–8962.
  • 15. F.C. Danert, C. Zampini, R. Ordóñez, L. Maldonado, E. Bedascarrasbure, M.I. Isla Argentinean propolis as non-conventional functional foods Nutr. Funct. Compos. Nat. Prod. Commun., 9 (2014) 167–170.
  • Y. Barlak, O. Deger, M. Colak, S.C. Karatayli, A.M. Bozdayi, F. Yucesan, Effect of Turkish propolis extracts on proteome of prostate cancer cell line Proteome Science, 9 (2011) 74.
  • G.C. Chan, K.W. Cheung, D.M. Sze, The immunomodulatory and anticancer properties of propolis Clin Rev Allergy Immunol, 44 (2013) 262–273.
  • M. Lofty, Biological activity of bee propolis in health and disease Asian Pacific Journal of Cancer Prevention, 7 (2006) 22–31.
  • S. Umthong, P. Phuwapraisirisan, S. Puthong, C. Chanchao In vitro antiproliferative activity of partially purified Trigona laeviceps propolis from Thailand on human cancer cell lines BMC Complementary and Alternative Medicine, 11 (2011) 37.
  • M.J. Valente, A.F. Baltazar, R. Henrique, L. Estevinho, M. Carvalho Biological activities of Portuguese propolis: Protection against free radical-induced erythrocyte damage and inhibition of human renal cancer cell growth in vitro Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association, 49 (2011) 86–92.
  • Wu, C. Omene, J. Karkoszka, M. Bosland, J. Eckard, C.B. Klein, K. Frenkel Caffeic acid phenethyl ester (CAPE), derived from a honeybee product propolis, exhibits a diversity of anti-tumor effects in pre-clinical models of human breast cancer Cancer Letters, 308 (2011) 43–53.
  • H. Fokt, A. Pereira, A.M. Ferreira, A. Cunha, C. Aguiar How do bees prevent hive infections? The antimicrobial properties of propolis A. Mendez-Vilas (Ed.), Current Research, Technology and Education Topics in Applied Microbiology and Microbial Biotechnology, vol. 1 Formatex, Badajoz, Spain (2010) 481–493 Microbiology Book Series- Number 2.
  • A. Salatino, C.C. Fernandes-Silva, A.A. Righi, M.L.F. Salatino, Propolis research and the chemistry of plant products. Nat. Prod. Rep., 28 (2011) 925-936.
  • V.A. Tagliacollo, R.O. Orsi, Quality of propolis commercialized in the informal market. Ciênc. Tecnol. Aliment., 31 (2011) 752-757.
  • I.M. Hernández, O. Cuesta-Rubio, M.C. Fernández, A.R. Pérez, R.M. Oca Porto, A.L. Piccinelli, L. Rastrelli, Studies on the constituents of yellow Cuban Propolis: GC-MS determination of triterpenoids and flavonoids. J. Agr. Food Chem., 58 (2010) 4725-4730.
  • T. Farooqui, A.A. Farooqui, Beneficial effects of propolis on human health and neurological diseases. Front. Biosci., 4 (2012) 779-793.
  • V. Bankova, M.C. Marcucci, S. Simova, N. Nikolova, A. Kujumgiev, S. Popov, Antibacterial diterpenic acids from Brazilian propolis. Z. Naturforsch. C., 51 (1996) 277-280.
  • V. Bankova, Chemical diversity of propolis and the problem of standardization. J. Ethnopharmacol., 100 (2005) 114-117.
  • R. Silva-Carvalho, V. Miranda-Gonçalves, A. Margarida Ferreira, S. M. Cardoso, A. J.F.N. Sobral, C. Almeida- Aguiar, F. Baltazar, Antitumoural and antiangiogenic activity of Portuguese propolis in in vitro and in vivo models, Journal of Functional Foods, 11 (20149) 160- 171.
  • D. Kasote, T. Suleman, W. Chen, M. Sandasi, A. Viljoen, S. Vuuren, Chemical profiling and chemometric analysis of South African Propolis, Biochemical Systematics and Ecology, 55 (2014) 156-163.
  • K. Sorkun, S. Bozcuk, Investigation of the effect of propolis on seed germination of some culture plants. X II. National Biology Conf. Edirne, Turkey, (1994), 54 -59.
  • H. Orhan, S. Marol, I.F. Hepsen, G. Sahin, Effect of some probable antioxidants on selenite-induced cataract formation and oxidative stress-related parameters in rats. Toxicology, 139 (1999) 219-232.
  • K. Ozturk, E. Kurt, M. Cerci, I. Emiroglu, U.U. Inan, S.S. Ilker, The effect of propolis extract in experimental chemical corneal injury. Ophthalmic Res., 32 (2000) 13-18.
  • M. Velikova, V. Bankova, K. Sorkun, S. Haucine, I. Tsvetkova, A. Kujumgiev, Propolis from Mediterraneaen region: Chemical composition and antimicrobial activity. Z. Naturforsch., 55 (2000) 1 -4 .
  • M. Velikova, V. Bankova, K. Sorkun, S. Popov, E. Kujumgiev, Chemical biological activity of propolis from Turkish and Bulgarian origin. Mellifera, 1 (2001) 57 -59.
  • D. Kolankaya, G. Selmanoğlu, K. Sorkun, B. Salih, Protective effects of Turkish propolis on alcohol- induced serum lipid changes and liver injury in male rats, Food Chemistry, 78 (2002) 213–217.
  • G. Girgin, T. Baydar, M. Ledochowski, H. Schennach, D.N. Bolukbası, K. Sorkun, B. Salih, G. Sahin, D. Fuchs, Immunomodulatory effects of Turkish propolis: Changes in neopterin release and tryptophan 48. R. Vrijien, L. Everaet, A. Boeye, Antiviral activity of degradation, Immunobiology, 214 (2009) 129–134.
  • S. Vatansever, K. Sorkun, D.İ. Gurhan, O.F. Kurt, E. Turkoz, O. Gençay, B. Salih, Propolis from Turkey induces apoptosis through activating caspases in human breast carcinoma cell lines, Acta Histochemica, 112 (2010), 546–556.
  • A. Temiz, A. Sener, A. Özkök Tüylü, K. Sorkun, B. Salih, Antibacterial activity of bee propolis samples from different geographical regions of Turkey against two foodborne pathogens, Salmonella Enteritidis and Listeria monocytogenes, Turkish Journal Biology, 35 (2011) 503-511.
  • N. Cihangir, K. Sorkun, B. Salih, Chemical composition and antibacterial activities of propolis collected from different regions of Turkey. Hacettepe Journal of Biology and Chemistry, 34 (2005) 59-67.
  • A. Uzel, K. Sorkun, Ö. Önçağ, Chemical compositions and antimicrobial ativities of four different Anatolian propolis samples. Microbiol. Res., 160 (2005) 189-195.
  • P. Güler, K. Sorkun, B. Salih, Effect of some Turkish Propolis on the product quantity of Agaricus bisporus (Lange.) Sing, Pak. J. Bot., 35 (2003) 439-447.
  • E. Debuyser, La propolis. Docteur en Pharmacie Thesis, Universite de Nantes, France, (1983) 82.
  • L. Meresta, T. Meresta, Antibacterial activity of flavanoid compounds of propolis, occurring in flora in Poland. Bull Vet Inst Pulawy 28-29, 61-63, Apic Abstr, (1990) 41, 1345.
  • A. Helbig, K.D. Thiel, Comparison of the antiviral activity of oxidizing caffeic acid and hydrocaffeic acid against Herpesvirus hominis types 1 and 0 in vitro. Pharmazie, 37 (1982) 603-604.
  • H. Ishitsuka, C, Ohsawa, T. Ohiwa, I. Umeda, Y. Suhara, Antipicornavirus flavone RO-09-0179. Antimicrob Agents Chemother, 22 (1982) 611-616.
  • I. Mucsi, Combined antiviral effect of flavanoids and 5-ethyl-2’-deoxyuridineon the multiplication of herpes virus. Acta Virol., 28 (1984) 395-400. flavones and potentiation by ascorbate, J. Gen. Virol., 69 (1988) 1749-1753.
  • M. Amoros, E. Lurton, J. Boustie, L. Girre, F. Sauvager, M. Cormier, Comparison of the anti-herpes simplex virus activities of propolis and 3-methylbut-2-enyl caffeate. J. Nat. Prod., 57 (1994) 644-647.
  • W. Greenaway, T. Scaysbrook, F.R. Whatley, The analysis of bud exudate of Populus x euramericana, and of propolis, by gas chromatography-mass spectrometry. Proc. R. Soc(Lond) Ser. B, 232 (1987) 249-272.
  • M. Seifert, E. Haslinger, Über die Inhaltsstoffe der Propolis. I. Liebigs Ann Chem, (1989) 1123-1126.
  • C. Garcia-Viguera, W. Greenaway, F.R. Whatley, Composition of propolis from two different Spanish regions. Z. Naturforsch, 47 (1992) 634-637.
  • M.C. Marcucci, M.L.F. Salatino, A. Salatino, Propolis constituents: waxes. Proc. SIMCRO(Brazilian Symposium of Chromatography), FM Lanças, Aguas de Sao Pedro, Brazil (1993) 37.
  • V.S. Bankova, R.S. Christov, A.D. Tejera, Lignans and other constituents of propolis from the Canary Islands, Phytochemistry, 49 (1998) 1411-1415.
  • S.J. Ory, C.B. Hammond, S.G. Yancy, R.W. Hendren, C.G Pitt, The effect of a biodegradable contraceptive capsule (Capronor) containing levonorgestrel on gonadotropin, estrogen, and progesterone levels. Am. J. Obstet. Gynecol., 145 (1983) 600–5.
  • I. Leoncini, Y. Le Conte, G. Costagliola, E. Plettner, A.L. Toth, M. Wang, Z. Huang, J.M. Bécard, Regulation of behavioral maturation by a primer pheromone produced by adult worker honey bees, Proc. Natl. Acad. Sci. U.S.A., 101 (2004) 17559–17564.

Türkiye’nin Batısında Üretilen Propolislerin Kimyasal Analizi

Year 2016, Volume: 44 Issue: 3, 327 - 338, 01.09.2016

Abstract

P ropolis veya arı zamkı farklı kimyasal özellikte bileşikler ve mineral maddeler içeren oldukça kompleks bir yapıya sahip doğal bir üründür ve insan sağlığı için önemlidir. Fakat propolisin toplama alanı ve zamanı ürün kalitesi için oldukça önemlidir. Bu amaçla bu çalışmada Türkiye’nin batısında bulunan Muğla ilinde üretilen propolislerin özellikleri ortaya çıkarılmıştır. Çam balı arıcılığının yoğun olarak yapıldığı Muğla ilinin 9 noktasından Eylül ayından Kasım ayına kadar 27 propolis örneği toplanmıştır. 27 adet propolis örneğinin GC-MS ile kimyasal madde tayini sonucunda, alkoller, aromatik alkoller, düz zincirli aldehitler, flavanonlar, düz zinzirli hidrokarbonlar, aromatik hidrokarbonlar, düz zincirli asit esterleri, aromatik asitler, aromatik esterler, aromatik asit esterleri, alifatik karboksilik asitler, alifatik karboksilik asit esterleri, alifatik esterler ve diğer kimyasal maddeler tespit edilmiştir. Propolis derişimleri, kullanılan propolis miktarına bağlı olarak % 0.71 ile % 13 arasında değişmiştir

References

  • V.D. Wagh, Propolis: a wonder bees product and its pharmacological potentials, Adv. Pharm. Sci., 2013 (2013) 308249.
  • V. Bankova, M. Popova, S. Bogdanov, A.G. Sabatini, Chemical composition of European propolis: expected and unexpected results. Z Naturforsch., 57 (2002) 530-533.
  • S. Castaldo, F. Capasso, Propolis, an old remedy used in modern medicine. Fitoterapia, 73 (2002) 1–6.
  • L. Monzote, O. Cuesta-Rubio, M. Campo Fernandez, I. Márquez Hernandez, J. Fraga, K. Pérez, M. Kerstens, L. Maes, P. Cos, In vitro antimicrobial assessment of Cuban propolis extracts. Mem. Inst. Oswaldo Cruz, 107 (2012) 978-984.
  • H. Shi, H. Yang, X. Zhang, L. Yu, Identification and quantification of phytochemical composition and anti-inflammatory and radical scavenging properties of methanolic extracts of Chinese propolis. J. Agr. Food Chem., 60 (2012) 12403-12410.
  • G.C. Chan, K.W Cheung, D.M. Sze, The immunomodulatory and anticancer properties of propolis. Clin. Rev. Allergy Immunol., 44 (2013) 262- 273.
  • M.I. Nieva Moreno, M.I. Isla, N.G. Cudmani, M.A. Vattuone, A. R. Sampietro, Screening of antibacterial activity of Amaicha del Valle (Tucumán, Argentina) própolis . Ethnopharmacol, 68 (1999) 97–102.
  • O. Koru, F. Toskay, C.H. Açıkel, Y.M. Tunca, M. Baysallar, G.A. Üsküdar, E. Akça, A. Özkök Tüylü, K. Sorkun, M. Tanyüksel, B. Salih, In vitro antimicrobial activity of propolis samples from different geographical origins against certain oral pathogens, Anaerobe, 13,3-4 (2007) 140-145.
  • N. Vera, E. Solorzano, R. Ordóñez, L. Maldonado, E. Bedascarrasbure, M.I. Isla Chemical composition of Argentinean propolis collected in extreme regions and its relation with antimicrobial and antioxidant activities, Nat Prod. Commun., 6 (2011) 823–827.
  • E. Solorzano, N. Vera, S. Cuello, R. Ordóñez, C. Zampini, L. Maldonado, E. Bedascarrasbure, M.I. Isla Chalcones in bioactive argentine propolis collected in arid environments Nat. Prod. Commun., 7 (2012) 879–882.
  • A.L. Salas, R.M. Ordóñez, C. Silva, L. Maldonado, E. Bedascarrasbure, M.I. Isla, I.C. Zampini, Antimicrobial activity of Argentinean propolis against Staphylococcus isolated of canine otitis J. Exp. Biol. Agric. Sci., 2 (2014) 197–207.
  • M.B. Agüero, M. González, B. Lima, L. Svetaz, M. Sánchez, S. Zacchino, G. Feresin, G. Schmeda- Hirschmann, J. Palermo, D. Wunderlin, A. Tapia Argentinean propolis from Zuccagnia punctata Cav. (Caesalpiniceae) exudates: phytochemical characterization and antifungal activity J. Agric. Food Chem., 58 (2010) 194–201.
  • M.I. Isla, M.I. Nieva Moreno, C. Zampini, E. Solórzano, C. Danert, A. Salas, N. Vera, J. Sayago, E. Bedascarrasbure, L. Maldonado, R. Ordóñez Argentine propolis: flavonoid and chalcone content and its relation with the functional properties T. Farroqui, A.A. Farooqui (Eds.), Beneficial Effects of Propolis on Human Health and Chronic Diseases, Nova Science Publishers, Hauppauge (New York) (2013) 161–170.
  • M.I. Nieva Moreno, I.C. Zampini, M. Ordóñez, M.A. Vattuone, M.I. Isla Evaluation of the cytotoxicity, mutagenicity and antimutagenicity of propolis from Amaicha del Valle, Tucumán, Argentina J. Agric. Food Chem., 53 (2005) 8957–8962.
  • 15. F.C. Danert, C. Zampini, R. Ordóñez, L. Maldonado, E. Bedascarrasbure, M.I. Isla Argentinean propolis as non-conventional functional foods Nutr. Funct. Compos. Nat. Prod. Commun., 9 (2014) 167–170.
  • Y. Barlak, O. Deger, M. Colak, S.C. Karatayli, A.M. Bozdayi, F. Yucesan, Effect of Turkish propolis extracts on proteome of prostate cancer cell line Proteome Science, 9 (2011) 74.
  • G.C. Chan, K.W. Cheung, D.M. Sze, The immunomodulatory and anticancer properties of propolis Clin Rev Allergy Immunol, 44 (2013) 262–273.
  • M. Lofty, Biological activity of bee propolis in health and disease Asian Pacific Journal of Cancer Prevention, 7 (2006) 22–31.
  • S. Umthong, P. Phuwapraisirisan, S. Puthong, C. Chanchao In vitro antiproliferative activity of partially purified Trigona laeviceps propolis from Thailand on human cancer cell lines BMC Complementary and Alternative Medicine, 11 (2011) 37.
  • M.J. Valente, A.F. Baltazar, R. Henrique, L. Estevinho, M. Carvalho Biological activities of Portuguese propolis: Protection against free radical-induced erythrocyte damage and inhibition of human renal cancer cell growth in vitro Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association, 49 (2011) 86–92.
  • Wu, C. Omene, J. Karkoszka, M. Bosland, J. Eckard, C.B. Klein, K. Frenkel Caffeic acid phenethyl ester (CAPE), derived from a honeybee product propolis, exhibits a diversity of anti-tumor effects in pre-clinical models of human breast cancer Cancer Letters, 308 (2011) 43–53.
  • H. Fokt, A. Pereira, A.M. Ferreira, A. Cunha, C. Aguiar How do bees prevent hive infections? The antimicrobial properties of propolis A. Mendez-Vilas (Ed.), Current Research, Technology and Education Topics in Applied Microbiology and Microbial Biotechnology, vol. 1 Formatex, Badajoz, Spain (2010) 481–493 Microbiology Book Series- Number 2.
  • A. Salatino, C.C. Fernandes-Silva, A.A. Righi, M.L.F. Salatino, Propolis research and the chemistry of plant products. Nat. Prod. Rep., 28 (2011) 925-936.
  • V.A. Tagliacollo, R.O. Orsi, Quality of propolis commercialized in the informal market. Ciênc. Tecnol. Aliment., 31 (2011) 752-757.
  • I.M. Hernández, O. Cuesta-Rubio, M.C. Fernández, A.R. Pérez, R.M. Oca Porto, A.L. Piccinelli, L. Rastrelli, Studies on the constituents of yellow Cuban Propolis: GC-MS determination of triterpenoids and flavonoids. J. Agr. Food Chem., 58 (2010) 4725-4730.
  • T. Farooqui, A.A. Farooqui, Beneficial effects of propolis on human health and neurological diseases. Front. Biosci., 4 (2012) 779-793.
  • V. Bankova, M.C. Marcucci, S. Simova, N. Nikolova, A. Kujumgiev, S. Popov, Antibacterial diterpenic acids from Brazilian propolis. Z. Naturforsch. C., 51 (1996) 277-280.
  • V. Bankova, Chemical diversity of propolis and the problem of standardization. J. Ethnopharmacol., 100 (2005) 114-117.
  • R. Silva-Carvalho, V. Miranda-Gonçalves, A. Margarida Ferreira, S. M. Cardoso, A. J.F.N. Sobral, C. Almeida- Aguiar, F. Baltazar, Antitumoural and antiangiogenic activity of Portuguese propolis in in vitro and in vivo models, Journal of Functional Foods, 11 (20149) 160- 171.
  • D. Kasote, T. Suleman, W. Chen, M. Sandasi, A. Viljoen, S. Vuuren, Chemical profiling and chemometric analysis of South African Propolis, Biochemical Systematics and Ecology, 55 (2014) 156-163.
  • K. Sorkun, S. Bozcuk, Investigation of the effect of propolis on seed germination of some culture plants. X II. National Biology Conf. Edirne, Turkey, (1994), 54 -59.
  • H. Orhan, S. Marol, I.F. Hepsen, G. Sahin, Effect of some probable antioxidants on selenite-induced cataract formation and oxidative stress-related parameters in rats. Toxicology, 139 (1999) 219-232.
  • K. Ozturk, E. Kurt, M. Cerci, I. Emiroglu, U.U. Inan, S.S. Ilker, The effect of propolis extract in experimental chemical corneal injury. Ophthalmic Res., 32 (2000) 13-18.
  • M. Velikova, V. Bankova, K. Sorkun, S. Haucine, I. Tsvetkova, A. Kujumgiev, Propolis from Mediterraneaen region: Chemical composition and antimicrobial activity. Z. Naturforsch., 55 (2000) 1 -4 .
  • M. Velikova, V. Bankova, K. Sorkun, S. Popov, E. Kujumgiev, Chemical biological activity of propolis from Turkish and Bulgarian origin. Mellifera, 1 (2001) 57 -59.
  • D. Kolankaya, G. Selmanoğlu, K. Sorkun, B. Salih, Protective effects of Turkish propolis on alcohol- induced serum lipid changes and liver injury in male rats, Food Chemistry, 78 (2002) 213–217.
  • G. Girgin, T. Baydar, M. Ledochowski, H. Schennach, D.N. Bolukbası, K. Sorkun, B. Salih, G. Sahin, D. Fuchs, Immunomodulatory effects of Turkish propolis: Changes in neopterin release and tryptophan 48. R. Vrijien, L. Everaet, A. Boeye, Antiviral activity of degradation, Immunobiology, 214 (2009) 129–134.
  • S. Vatansever, K. Sorkun, D.İ. Gurhan, O.F. Kurt, E. Turkoz, O. Gençay, B. Salih, Propolis from Turkey induces apoptosis through activating caspases in human breast carcinoma cell lines, Acta Histochemica, 112 (2010), 546–556.
  • A. Temiz, A. Sener, A. Özkök Tüylü, K. Sorkun, B. Salih, Antibacterial activity of bee propolis samples from different geographical regions of Turkey against two foodborne pathogens, Salmonella Enteritidis and Listeria monocytogenes, Turkish Journal Biology, 35 (2011) 503-511.
  • N. Cihangir, K. Sorkun, B. Salih, Chemical composition and antibacterial activities of propolis collected from different regions of Turkey. Hacettepe Journal of Biology and Chemistry, 34 (2005) 59-67.
  • A. Uzel, K. Sorkun, Ö. Önçağ, Chemical compositions and antimicrobial ativities of four different Anatolian propolis samples. Microbiol. Res., 160 (2005) 189-195.
  • P. Güler, K. Sorkun, B. Salih, Effect of some Turkish Propolis on the product quantity of Agaricus bisporus (Lange.) Sing, Pak. J. Bot., 35 (2003) 439-447.
  • E. Debuyser, La propolis. Docteur en Pharmacie Thesis, Universite de Nantes, France, (1983) 82.
  • L. Meresta, T. Meresta, Antibacterial activity of flavanoid compounds of propolis, occurring in flora in Poland. Bull Vet Inst Pulawy 28-29, 61-63, Apic Abstr, (1990) 41, 1345.
  • A. Helbig, K.D. Thiel, Comparison of the antiviral activity of oxidizing caffeic acid and hydrocaffeic acid against Herpesvirus hominis types 1 and 0 in vitro. Pharmazie, 37 (1982) 603-604.
  • H. Ishitsuka, C, Ohsawa, T. Ohiwa, I. Umeda, Y. Suhara, Antipicornavirus flavone RO-09-0179. Antimicrob Agents Chemother, 22 (1982) 611-616.
  • I. Mucsi, Combined antiviral effect of flavanoids and 5-ethyl-2’-deoxyuridineon the multiplication of herpes virus. Acta Virol., 28 (1984) 395-400. flavones and potentiation by ascorbate, J. Gen. Virol., 69 (1988) 1749-1753.
  • M. Amoros, E. Lurton, J. Boustie, L. Girre, F. Sauvager, M. Cormier, Comparison of the anti-herpes simplex virus activities of propolis and 3-methylbut-2-enyl caffeate. J. Nat. Prod., 57 (1994) 644-647.
  • W. Greenaway, T. Scaysbrook, F.R. Whatley, The analysis of bud exudate of Populus x euramericana, and of propolis, by gas chromatography-mass spectrometry. Proc. R. Soc(Lond) Ser. B, 232 (1987) 249-272.
  • M. Seifert, E. Haslinger, Über die Inhaltsstoffe der Propolis. I. Liebigs Ann Chem, (1989) 1123-1126.
  • C. Garcia-Viguera, W. Greenaway, F.R. Whatley, Composition of propolis from two different Spanish regions. Z. Naturforsch, 47 (1992) 634-637.
  • M.C. Marcucci, M.L.F. Salatino, A. Salatino, Propolis constituents: waxes. Proc. SIMCRO(Brazilian Symposium of Chromatography), FM Lanças, Aguas de Sao Pedro, Brazil (1993) 37.
  • V.S. Bankova, R.S. Christov, A.D. Tejera, Lignans and other constituents of propolis from the Canary Islands, Phytochemistry, 49 (1998) 1411-1415.
  • S.J. Ory, C.B. Hammond, S.G. Yancy, R.W. Hendren, C.G Pitt, The effect of a biodegradable contraceptive capsule (Capronor) containing levonorgestrel on gonadotropin, estrogen, and progesterone levels. Am. J. Obstet. Gynecol., 145 (1983) 600–5.
  • I. Leoncini, Y. Le Conte, G. Costagliola, E. Plettner, A.L. Toth, M. Wang, Z. Huang, J.M. Bécard, Regulation of behavioral maturation by a primer pheromone produced by adult worker honey bees, Proc. Natl. Acad. Sci. U.S.A., 101 (2004) 17559–17564.
There are 55 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Aslı Özkök This is me

Kadriye Sorkun This is me

Bekir Salih This is me

Publication Date September 1, 2016
Published in Issue Year 2016 Volume: 44 Issue: 3

Cite

APA Özkök, A., Sorkun, K., & Salih, B. (2016). The Chemical Analysis of Propolis, Which are Produced in Western of Turkey. Hacettepe Journal of Biology and Chemistry, 44(3), 327-338.
AMA Özkök A, Sorkun K, Salih B. The Chemical Analysis of Propolis, Which are Produced in Western of Turkey. HJBC. September 2016;44(3):327-338.
Chicago Özkök, Aslı, Kadriye Sorkun, and Bekir Salih. “The Chemical Analysis of Propolis, Which Are Produced in Western of Turkey”. Hacettepe Journal of Biology and Chemistry 44, no. 3 (September 2016): 327-38.
EndNote Özkök A, Sorkun K, Salih B (September 1, 2016) The Chemical Analysis of Propolis, Which are Produced in Western of Turkey. Hacettepe Journal of Biology and Chemistry 44 3 327–338.
IEEE A. Özkök, K. Sorkun, and B. Salih, “The Chemical Analysis of Propolis, Which are Produced in Western of Turkey”, HJBC, vol. 44, no. 3, pp. 327–338, 2016.
ISNAD Özkök, Aslı et al. “The Chemical Analysis of Propolis, Which Are Produced in Western of Turkey”. Hacettepe Journal of Biology and Chemistry 44/3 (September 2016), 327-338.
JAMA Özkök A, Sorkun K, Salih B. The Chemical Analysis of Propolis, Which are Produced in Western of Turkey. HJBC. 2016;44:327–338.
MLA Özkök, Aslı et al. “The Chemical Analysis of Propolis, Which Are Produced in Western of Turkey”. Hacettepe Journal of Biology and Chemistry, vol. 44, no. 3, 2016, pp. 327-38.
Vancouver Özkök A, Sorkun K, Salih B. The Chemical Analysis of Propolis, Which are Produced in Western of Turkey. HJBC. 2016;44(3):327-38.

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