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İdrar Torbasında Mor Tonlar: Nadir Görülen Ancak Çarpıcı Bir Klinik Fenomen

Year 2025, Volume: 22 Issue: 4, 842 - 844, 25.12.2025
https://doi.org/10.35440/hutfd.1674873

Abstract

Mor İdrar Torbası Sendromu (PUBS), genellikle ileri yaşta, uzun süreli idrar sondası kullanan ve yatağa bağımlı bireylerde gözlenen nadir bir klinik durumdur. Triptofan metabolizması ürünleri ile bazı bakteriyel enzimlerin etkileşimi sonucu idrar torbasında belirgin bir mor renk değişimi meydana gelir. Son dönemde geçirdiği inme sonrası yatağa bağımlı hale gelen 75 yaşındaki kadın hasta, idrar torbasında oluşan mor renk değişimi nedeniyle ailesi tarafından acil servise getirildi. Fizik muayenesinde sol taraf hemipleji ve suprapubik bölgede hafif hassasiyet tespit edildi. Laboratuvar incelemelerinde anlamlı patoloji saptanmadı; ancak idrar kültüründe Escherichia coli üremesi mevcuttu. Kateter değiştirildi ve aileye durumun benign bir seyir izlediği, uygun antibiyotik tedavisi ile iyileşme sağlanabileceği bilgisi verildi. Hasta oral antibiyotik reçetesiyle taburcu edildi. PUBS, nadir görülse de dikkat çekici görünümü nedeniyle hasta ve yakınlarında endişeye yol açabilir. Acil serviste görevli hekimlerin bu sendromu tanıması, gereksiz tetkiklerin önüne geçilmesini sağlar. Erken fark edilmesi, uygun antibiyotik tedavisi ve kateter yönetimi ile genellikle kısa sürede geriler.

References

  • 1. Pillai BP, Chong VH, Yong AM. Purple urine bag syndrome. Singapore Med J. 2009;50(5):e193-e194.
  • 2. Rossi M, Johnson DW, Morrison M, et al. Synbiotics Easing Renal Failure by Improving Gut Microbiology (SYNERGY): A Randomized Trial. Clin J Am Soc Nephrol. 2016;11(2):223-231.
  • 3. Banoglu E, Jha GG, King RS. Hepatic microsomal metabolism of indole to indoxyl, a precursor of indoxyl sulfate. Eur J Drug Metab Pharmacokinet. 2001;26(4):235-240.
  • 4. Banoglu E, King RS. Sulfation of indoxyl by human and rat aryl (phenol) sulfotransferases to form indoxyl sulfate. Eur J Drug Metab Pharmacokinet. 2002;27(2):135-140.
  • 5. Dealler SF, Hawkey PM, Millar MR. Enzymatic degradation of urinary indoxyl sulfate by Providencia stuartii and Klebsiella pneumoniae causes the purple urine bag syndrome. J Clin Microbiol. 1988;26(10):2152-2156.
  • 6. Sabanis N, Paschou E, Papanikolaou P, Zagkotsis G. Purple Urine Bag Syndrome: More Than Eyes Can See. Curr Urol. 2019;13(3):125-132.
  • 7. Dealler SF, Belfield PW, Bedford M, Whitley AJ, Mulley GP. Purple urine bags. J Urol. 1989;142(3):769-770.
  • 8. Mantani N, Ochiai H, Imanishi N, Kogure T, Terasawa K, Tamura J. A case-control study of purple urine bag syndrome in geriatric wards. J Infect Chemother. 2003;9(1):53-57.
  • 9. Ishida T, Ogura S, Kawakami Y. Nihon Ronen Igakkai Zasshi. 1999;36(11):826-829.

Purple Hues in the Urinary Bag: A Rare but Striking Clinical Phenomenon

Year 2025, Volume: 22 Issue: 4, 842 - 844, 25.12.2025
https://doi.org/10.35440/hutfd.1674873

Abstract

Purple Urine Bag Syndrome (PUBS) represents a rare but striking clinical entity, predominantly affecting elderly, immobilized patients with long-term urinary catheterization. The purple discoloration of the urine collection system stems from bacterial enzymatic interactions with tryptophan metabolites. A 75-year-old woman, recently bedridden following a cerebrovascular event, was brought to the emergency department due to an unusual purple hue in her urine collection bag. On examination, she exhibited left-sided hemiplegia and mild suprapubic tenderness. Laboratory findings were mostly within normal limits, except for a positive urine culture growing Escherichia coli. The catheter was replaced, and the patient’s family was reassured about the benign nature of the condition. The patient was discharged with appropriate oral antibiotic treatment targeting the urinary tract infection. Although benign, PUBS may cause significant psychological distress due to its unusual appearance. Familiarity with this condition among emergency physicians is crucial to avoid unnecessary diagnostic or therapeutic procedures. Timely recognition and proper management, including catheter care and targeted antibiotic therapy, usually result in rapid resolution.n.

References

  • 1. Pillai BP, Chong VH, Yong AM. Purple urine bag syndrome. Singapore Med J. 2009;50(5):e193-e194.
  • 2. Rossi M, Johnson DW, Morrison M, et al. Synbiotics Easing Renal Failure by Improving Gut Microbiology (SYNERGY): A Randomized Trial. Clin J Am Soc Nephrol. 2016;11(2):223-231.
  • 3. Banoglu E, Jha GG, King RS. Hepatic microsomal metabolism of indole to indoxyl, a precursor of indoxyl sulfate. Eur J Drug Metab Pharmacokinet. 2001;26(4):235-240.
  • 4. Banoglu E, King RS. Sulfation of indoxyl by human and rat aryl (phenol) sulfotransferases to form indoxyl sulfate. Eur J Drug Metab Pharmacokinet. 2002;27(2):135-140.
  • 5. Dealler SF, Hawkey PM, Millar MR. Enzymatic degradation of urinary indoxyl sulfate by Providencia stuartii and Klebsiella pneumoniae causes the purple urine bag syndrome. J Clin Microbiol. 1988;26(10):2152-2156.
  • 6. Sabanis N, Paschou E, Papanikolaou P, Zagkotsis G. Purple Urine Bag Syndrome: More Than Eyes Can See. Curr Urol. 2019;13(3):125-132.
  • 7. Dealler SF, Belfield PW, Bedford M, Whitley AJ, Mulley GP. Purple urine bags. J Urol. 1989;142(3):769-770.
  • 8. Mantani N, Ochiai H, Imanishi N, Kogure T, Terasawa K, Tamura J. A case-control study of purple urine bag syndrome in geriatric wards. J Infect Chemother. 2003;9(1):53-57.
  • 9. Ishida T, Ogura S, Kawakami Y. Nihon Ronen Igakkai Zasshi. 1999;36(11):826-829.
There are 9 citations in total.

Details

Primary Language English
Subjects Emergency Medicine
Journal Section Case Report
Authors

Zahit Dönmez 0009-0009-8833-2141

Hüseyin Avni Demir 0000-0003-2891-9345

Eyyup Sabri Şeyhanlı 0000-0002-1800-1357

Ahmet Celal Özsoy 0009-0004-5849-088X

Muhammed Tabası 0009-0006-3529-3394

Abdul Samed Rayan 0009-0005-0543-112X

Submission Date April 12, 2025
Acceptance Date August 11, 2025
Early Pub Date December 15, 2025
Publication Date December 25, 2025
Published in Issue Year 2025 Volume: 22 Issue: 4

Cite

Vancouver 1.Dönmez Z, Demir HA, Şeyhanlı ES, Özsoy AC, Tabası M, Rayan AS. Purple Hues in the Urinary Bag: A Rare but Striking Clinical Phenomenon. Harran Üniversitesi Tıp Fakültesi Dergisi [Internet]. 2025 Dec. 1;22(4):842-4. Available from: https://izlik.org/JA53MB47XA

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