Sirozlu Hastalarda Beslenme Durumunun Değerlendirilmesi

Abstract

Amaç: Sirozlu hastalarda beslenme bozukluğu sık olup, beslenme durumunun değerlendirildiği standart bir test yoktur. Sirozlu hastalarda malnütrisyon sıklığı ve malnütrisyonun asit, Child-Pugh skoru ve Model for End Stage Liver Disease (MELD) skoru ile ilişkisi araştırılmıştır.
Materyal ve metod: Bu prospektif çalışmada sirozda beslenme durumunun değerlendirilmesinde Subjektif Global Değerlendirme (SGA), Royal Free Hospital nutrisyonel önceliklendirme aracı (RFH-NPT) ve Mini Nütrisyonel Değerlendirme (MNA) testleri kullanılmıştır. 
Bulgular: Sirotik 80 hastanın, 46’sı erkek (%57,5), yaş ortalaması 54,40±11,77, yaş aralığı 18-75, kontrol grubunun 44’ü erkek (%55), yaş ortalaması 53,85±9,59, yaş dağılımı 18-75 idi. SGA, RFH-NPT ve MNA testine göre sirozlu hastalarda kontrol grubuna göre malnütrisyon sıklığı ileri derecede anlamlı olarak yüksek oranda saptandı (sırasıyla p<0,001, p=0,001, p<0,003).  Hasta grubunda MELD skoru, Child-Pugh skoru ve asit varlığı ile malnütrisyon gelişimi riski arasında kolerasyon saptanmadı. 
Sonuç: Sirozlu hastalarda kontrol grubuna göre malnütrisyon daha sıktır. Sirotik tüm hastalarda asit, Child-Pugh ve MELD skorundan bağımsız malnütrisyon taraması yapılmalıdır.

Keywords

• Karaciğer Sirozu
• Malnütrisyon
• SGA
• RFH-NPT
• MNA
• MELD
• Child-Pugh

Ethical Statement

Ethical approval for the study was obtained from the Ethics Committee of Harran University Faculty of Medicine (approval no: HRÜ/19.06.28, date: June 13, 2009). This study is derived from a postgraduate thesis (National Thesis Center No: 627293, Thesis Date: 2019).

Evaluation of Nutritional Status in Patients with Cirrhosis

Abstract

Background: Nutritional deficiencies are common in patients with cirrhosis; there is no standard test to assess nutritional status in patients with cirrhosis. This study investigated the prevalence of malnutrition in patients with cirrhosis and examined the association of malnutrition with ascites, Child-Pugh classification, and model of end stage liver disease (MELD) score.
Materials and Methods: Nutritional status in cirrhosis was assessed using the Subjective Global Assessment (SGA), the Royal Free Hospital Nutritional Prioritizing Tool (RFH-NPT), and the Mini Nutritional Assessment (MNA) prospectively.
Results: Of 80 cirrhotic patients, 46 were male (57.5%), and the mean age was 54.40±11.77 years (range: 18-75). In the control group, 44 of 80 were male (55%), and the mean age was 53.85±9.59 years (range: 18-75). Compared with controls according to SGA, RFH-NPT and MNA tests, malnutrition prevalence was significantly higher in cirrhotic patients than in controls (p<0.001, p<0.001, and p<0.003, respectively). No correlation was found between malnutrition risk and MELD score, Child-Pugh score, or the presence of ascites in the patient group.
Conclusion: Malnutrition is frequent in patients with cirrhosis. All cirrhotic patients should be screened for malnutrition, irrespective of ascites, Child-Pugh class, or MELD score.

Keywords

• Liver Cirrhosis
• Malnutrition
• SGA
• RFH-NPT
• MNA
• MELD
• Child-Pugh

Ethical Statement

Ethical approval for the study was obtained from the Ethics Committee of Harran University Faculty of Medicine (approval no: HRÜ/19.06.28, date: June 13, 2009).

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