Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome): Case Report
Year 2016,
Volume: 13 Issue: 1, 84 - 87, 28.04.2016
Hakan Tanrıverdi
Fırat Uygur
Bülent Altınsoy
,
Fatma Erboy
,
Ömer Yazgan
Figen Atalay
Abstract
Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic necrotizing vasculitis characterized by
tissue and blood eosinophilia. Several drugs including leukotriene receptor antagonists (LTRAs) are
suspected to trigger EGPAdevelopment. Here, we present a case of EGPAunrelated to LTRAs.
References
- 1.Groh M, Pagnoux C, Baldini C, Bel E, Bottero P,
Cottin V et al. Eosinophilic granulomatosis with
polyangiitis (Churg–Strauss) (EGPA) Consensus Task
Force recommendations for evaluation and
management. Eur J Intern Med. 2015;26 (7):545-53.
http://dx.doi.org/10.1016/j.ejim.2015.04.022
- 2.Samson M, Puéchal X, Devilliers H, Ribi C, Cohen P,
Stern M et al. Long-term outcomes of 118 patients with
eosinophilic granulomatosis with polyangiitis (ChurgStrauss
syndrome) enrolled in two prospective trials. J
Autoimmun 2013;43:60-9.
- 3.Ramentol-Sintas M, Martínez-Valle F, Solans-Laqué R.
Churg–Strauss Syndrome: An evolving paradigm.
Autoimmun Rev 2012;12(2):235–40.
Masi AT
1
- 4. , Hunder GG, Lie JT, Michel BA, Bloch DA, Arend
WP, et al. The American College of Rheumatology 1990
criteria for the classification of Churg-Strauss syndrome
(allergic granulomatosis and angiitis). Arthritis Rheum.
1990;33(8):1094-100.
- 5.Yıldız F, Zorludemir S, Erken E. Montelukast ilişkili
Churg Strauss sendromu: Üç olgu. Cukurova Med J
2014;39(2):347-52
- 6.Bibby S, Healy B, Steele R, Kumareswaran K, Nelson H,
Beasley R. Association between leukotriene receptor
antagonist therapy and Churg–Strauss syndrome: an
analysis of the FDA AERS database. Thorax
2010;65(2):132–8
- 7.Hauser T, Mahr A, Metzler C, Coste J, Sommerstein R,
Gross WL, e t a l. The l eucotri ene r e c eptor
antagonistmontelukast and the risk of Churg–Strauss
Sy n d r ome : a c a s e - c r o ss o v e r st u d y. Th o r a x
2008;63(8):677–82.
- 8.Abril A, Calamia KT, Cohen MD. The Churg Strauss
syndrome (Allergic granulomatous angiitis): Review and
update. Semin Arthritis Rheum 2003;33:106-14.
Polianjitisle Seyreden Eozinofilik Granülomatozis (Churg Strauss Sendromu): Olgu Sunumu
Year 2016,
Volume: 13 Issue: 1, 84 - 87, 28.04.2016
Hakan Tanrıverdi
Fırat Uygur
Bülent Altınsoy
,
Fatma Erboy
,
Ömer Yazgan
Figen Atalay
Abstract
Polianjitisle birlikte seyreden eozinofilik granülomatozis (Churg Strauss sendromu), nadir, sıklıkla solunum
sistemini tutan ve özellikle küçük ve orta çaplı damarları etkileyen, astım ve doku eozinofilisi ile karakterize,
sistemik nekrotizan bir vaskülittir. Lökotrien antagonistlerini de içeren pek çok ilacın bu hastalığın
gelişiminde rolü olduğundan şüphelenilmektedir. Biz de klinik ve radyolojik bulgularla tanı alan ve lökotrien
reseptör antagonistleri ile ilişkili olmadığını düşündüğümüz bir olguyu sunmak istedik.
References
- 1.Groh M, Pagnoux C, Baldini C, Bel E, Bottero P,
Cottin V et al. Eosinophilic granulomatosis with
polyangiitis (Churg–Strauss) (EGPA) Consensus Task
Force recommendations for evaluation and
management. Eur J Intern Med. 2015;26 (7):545-53.
http://dx.doi.org/10.1016/j.ejim.2015.04.022
- 2.Samson M, Puéchal X, Devilliers H, Ribi C, Cohen P,
Stern M et al. Long-term outcomes of 118 patients with
eosinophilic granulomatosis with polyangiitis (ChurgStrauss
syndrome) enrolled in two prospective trials. J
Autoimmun 2013;43:60-9.
- 3.Ramentol-Sintas M, Martínez-Valle F, Solans-Laqué R.
Churg–Strauss Syndrome: An evolving paradigm.
Autoimmun Rev 2012;12(2):235–40.
Masi AT
1
- 4. , Hunder GG, Lie JT, Michel BA, Bloch DA, Arend
WP, et al. The American College of Rheumatology 1990
criteria for the classification of Churg-Strauss syndrome
(allergic granulomatosis and angiitis). Arthritis Rheum.
1990;33(8):1094-100.
- 5.Yıldız F, Zorludemir S, Erken E. Montelukast ilişkili
Churg Strauss sendromu: Üç olgu. Cukurova Med J
2014;39(2):347-52
- 6.Bibby S, Healy B, Steele R, Kumareswaran K, Nelson H,
Beasley R. Association between leukotriene receptor
antagonist therapy and Churg–Strauss syndrome: an
analysis of the FDA AERS database. Thorax
2010;65(2):132–8
- 7.Hauser T, Mahr A, Metzler C, Coste J, Sommerstein R,
Gross WL, e t a l. The l eucotri ene r e c eptor
antagonistmontelukast and the risk of Churg–Strauss
Sy n d r ome : a c a s e - c r o ss o v e r st u d y. Th o r a x
2008;63(8):677–82.
- 8.Abril A, Calamia KT, Cohen MD. The Churg Strauss
syndrome (Allergic granulomatous angiitis): Review and
update. Semin Arthritis Rheum 2003;33:106-14.