The Change Of Average Platelet Volume and Platelets Count in Saphenous Vein Embolization Using By Cyanoakrilate

Year 2019, Volume: 16 Issue: 2, 272 - 279, 29.08.2019

Cengiz Güven , Mevlüt Doğukan

https://doi.org/10.35440/hutfd.534120

Cited By: 1

Abstract

Background: In the present study, it is aimed to determine the
intervention-related change in the mean platelet volume (MPV) and platelet
count in saphenous vein embolization performed using cyanoacrylate in chronic
venous stasis and varicose treatment, as well as explaining the possible venous
thromboembolism events.

Methods:
60 patients involved in the present study were selected from the patients, who
had varicose and chronic venous stasis and who applied to the Cardiovascular
Surgery Polyclinic of Medical Faculty of Adıyaman University. The files of
patients undergone saphenous vein embolization using CA were performed
digitally and their USG and laboratory results were analyzed. Among 437
patients, 60 patients’ undergone hemogram and biochemical examination before
and after the intervention were involved in the present study. The preoperative
(pre-op) and postoperative (post-op) platelet counts and mean platelet volumes
of the patients were analyzed.

Results: When
compared to the pre-op period, no significant change was observed on 1^st post-ophour
and 1^stpost-op month (p ˃ 0.05), however the MPV value observed on the
3^rd post-op day was significantly higher than the pre-op period (p ˂ 0.05). The MPV value observed on the 3^rd
post-op day was statistically higher than on 1^st post-op hour
(p ˂ 0.05) and the MPV value observed on the 1^st
post-op month was statistically significantly lower than on 3^rd post-op
day (p ˂ 0.05).

Conclusion: MPV did not significantly increase from the normal values on the 1^st
postoperative day, whereas it significantly increased on the 3^rd
postoperative day. Assuming that MPV is related with the increasing
thrombogenicity, it can be stated that the saphenous vein embolization by using
CA that is one of the minimally invasive methods used in varicose treatment may
cause thromboembolic events in the early pre-op period (in the first week). 

Keywords

Mean platelet volume, Varicose, Cyanoacrylate, Thromboembolism

Siyanoakrilat ile Safen Ven Embolizasyonunda Ortalama Trombosit Hacmi ve Trombosit Sayısının Değişimi

Abstract

Amaç: Bu çalışmada amacımız kronik venöz yetmezlik ve varis tedavisinde
siyanoakrilat (CA) ile yapılan safen ven embolizasyonunda işleme bağlı ortalama
trombosit hacminin (MPV) ve trombosit sayısının değişimini saptamak ve
oluşabilecek venöz tromboembolizm olaylarına açıklık getirmektir.

Materyal ve
Metot: Bu çalışmaya dâhil
edilen 60 hasta Adıyaman Üniversitesi Tıp Fakültesi Kalp ve Damar Cerrahisine
Polikliniğine başvuran varis ve kronik venöz yetersizliği olan hastalardan
seçildi. CA ile safen ven embolizasyonu yapılan hastaların dosya taraması
dijital ortamda yapılarak USG ve laboratuvar tetkikleri incelendi. İşlem
yapılan toplam 437 hastadan işlem öncesi ve sonrası hemogram ve biyokimya
tetkikleri alınan60hasta çalışmaya dahil edildi. Hastaların işlem öncesi ve
sonrası trombosit sayısı ve ortalama trombosit hacmi değerlendirildi.

Bulgular: Postoperatif(post-op) 1. Saat ve 1.ay MPV değeri preoperatif (pre-op)
döneme göre anlamlı (p ˃ 0.05) değişim göstermezken post-op 3.gün MPV
değeri pre-op döneme göre anlamlı (p ˂ 0.05)
artış gösterdiği tespit edildi. Post-op 3.gün MPV değeri post op 1.saate
göre anlamlı (p ˂ 0.05) artış ve post-op 1.ay MPV
değeri post-op 3.güne göre anlamlı (p ˂ 0.05)
düşüş göstermiştir.

Sonuç: MPV işlemden 1 gün sonra normal değerlerden anlamlı artış göstermez
iken post op 3. günde anlamlı artış gösterdi. MPV’ün artan trombojenite ile
ilişkili olduğunu varsayarsak varis tedavisinde kullanılan minimal invaziv
yöntemlerden olan CA ile safen ven embolizasyonu post-op erken (İlk bir hafta
içinde) dönemde tromboembolik olaylara sebep olabilmektedir.

     

Keywords

Mean platelet volüm, Varis, Siyanoakrilat, Tromboembolizm

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