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Histological Evaluation of the Surgically-obtained Specimens over Eleven Years

Year 2008, Volume: 5 Issue: 2, 41 - 45, 01.08.2008

Abstract

Objective: The results of the surgically-obtained specimens at Yüzüncü Yıl University Medical Faculty Ophthalmology Clinic over 11 years were evaluated. Material and Methods: Surgically-obtained specimens at the Ophthalmology Clinic was evaluated in a single pathology laboratory between 01.12.1995 and 30.06.2007 retrospectively. Results: A total of 186 surgically-obtained specimens were found. The most common area of histological diagnosis was the eyelids 112 specimens, 60.2% , followed by conjunctiva 63 specimens, 33.9% , uvea 4 specimens, 2.2% , caruncle 2 specimens, 1.1% , orbit 2 specimens, 1.1% , sclera 1 specimen, 0.5% , lacrimal drainage system 1 specimen, 0.5% , and retina 1 specimen, 0.5% . Of the specimens, 24 were malign, 5 were pre-malign, 37 were inflammatory, and 120 were benign processes. The distribution of the malign processes was as follows: Basal cell carcinoma was reported in 17 cases, squamous cell carcinoma in 9 cases, malign melanoma in 4 cases, lymphoma in 1 case, retinoblastoma in 1 case, basosquamous carcinoma in 1 case, and atypical fibroxanthoma in 1 case. Conclusion: Histological examination revealed probably life-threatening pathologies in 15.6% of cases

References

  • Grossniklaus HE, Green WR, Luckenbach M, Chan CC. Conjunctival lesions in adults. A clinical and histopathological review. Cornea 1987; 6: 78–116.
  • Grossniklaus HE, McLean IW. Cutaneous melanoma of the eyelid. Clinicopathologic features. Ophthalmology 1991; 98:1867–1873.
  • Polito E, Leccisotti A. Epithelial malignancies of the lacrimal gland: survival rates after extensive and conservative therapy. Ann Ophthalmol 1993; 25: 422–426.
  • Tesluk GC. Eyelid lesions: Incidence and comparison of benign and malignant lesions. Ann Ophthalmol 1985;17:704-707.
  • Spraul CW ve Grossniklaus HE. Analysis of 24,444 surgical specimens accessioned over 55 years in an ophthalmic pathology laboratory. Int Ophthalmology 1998; 21: 283-304.
  • Bernardini FP. Management of malignant and benign eyelid lesions. Curr Opin Ophthalmol 2006;17:480-484.
  • Shields JA, Shields CL, Scartozzi R. Survey of 1264 patients with orbital tumors and simulating lesions: The 2002 Montgomery Lecture, part 1.Ophthalmology 2004;111:997-1008.

Onbir Yıllık Cerrahi Vakalarımızın Histolojik İnceleme Sonuçları

Year 2008, Volume: 5 Issue: 2, 41 - 45, 01.08.2008

Abstract

Amaç: Yüzüncü Yıl Üniversitesi Tıp Fakültesi Göz Hastalıkları Anabilim Dalı’nda yapılan operasyonlarda eksize edilen doku örneklerinin histolojik sonuçlarının değerlendirilmesi. Gereç ve Yöntemler: 01.12.1995- 30.06.2007 tarihleri arasındaki yaklaşık 11 yıllık dönemde Anabilim Dalımız’da yapılan operasyonlarda eksize edilip patolojik tanı alan toplam doku örneklerinin sonuçları kayıtlardan alınarak incelendi. Bulgular: Çalışmada 186 örneğe patoloji tanı konduğu tespit edildi. En sık histolojik tanı alan bölge olan göz kapaklarını 112 doku örneği, %60,2 , konjonktiva 63 doku örneği, %33,9 , uvea 4 doku örneği, %2,2 , karunkül 2 doku örneği, %1,1 , orbita 2 doku örneği, %1,1 , sklera 1 doku örneği, %0,5 , lakrimal kanal 1 doku örneği, %0,5 , ve retina 1 doku örneği, %0,5 takip etti. Yapılan histolojik değerlendirmede 186 dokunun 24’ünde malign, 5’inde premalign, 37’sinde inflamatuar, ve 120’inde benign oluşum saptandı. Doku örneklerinin %15,6‘sında hayatı tehdit edebilen patolojiler tespit edildi. Malign oluşumların dağılımı şu şekildedir: Bazal hücreli karsinom 17 olguda, Skuamoz hücreli karsinom 9 olguda, malign melanom 4 olguda, bazoskuamöz karsinom 1 olguda, lenfoma 1 olguda, retinoblastom 1 olguda, ve atipik fibroksantom 1 olguda tespit edildi. Sonuç: Patolojik tanı alan doku örneklerinin % 15,6’sında hayatı tehdit edebilen patolojiler tespit edildi

References

  • Grossniklaus HE, Green WR, Luckenbach M, Chan CC. Conjunctival lesions in adults. A clinical and histopathological review. Cornea 1987; 6: 78–116.
  • Grossniklaus HE, McLean IW. Cutaneous melanoma of the eyelid. Clinicopathologic features. Ophthalmology 1991; 98:1867–1873.
  • Polito E, Leccisotti A. Epithelial malignancies of the lacrimal gland: survival rates after extensive and conservative therapy. Ann Ophthalmol 1993; 25: 422–426.
  • Tesluk GC. Eyelid lesions: Incidence and comparison of benign and malignant lesions. Ann Ophthalmol 1985;17:704-707.
  • Spraul CW ve Grossniklaus HE. Analysis of 24,444 surgical specimens accessioned over 55 years in an ophthalmic pathology laboratory. Int Ophthalmology 1998; 21: 283-304.
  • Bernardini FP. Management of malignant and benign eyelid lesions. Curr Opin Ophthalmol 2006;17:480-484.
  • Shields JA, Shields CL, Scartozzi R. Survey of 1264 patients with orbital tumors and simulating lesions: The 2002 Montgomery Lecture, part 1.Ophthalmology 2004;111:997-1008.
There are 7 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Adil Kılıç This is me

Mustafa Kösem This is me

Adnan Çınal This is me

Adem Gül This is me

Tekin Yaşar This is me

Gülay Bulut This is me

Ahmet Demirok This is me

Publication Date August 1, 2008
Published in Issue Year 2008 Volume: 5 Issue: 2

Cite

Vancouver Kılıç A, Kösem M, Çınal A, Gül A, Yaşar T, Bulut G, Demirok A. Onbir Yıllık Cerrahi Vakalarımızın Histolojik İnceleme Sonuçları. Harran Üniversitesi Tıp Fakültesi Dergisi. 2008;5(2):41-5.

Harran Üniversitesi Tıp Fakültesi Dergisi  / Journal of Harran University Medical Faculty