Research Article

Investigation of The Effect of Intermediate Dose Calculation Module on Dose Dıstrıbutıon in Lung Cancer Radiotherapy Patients

Volume: 5 Number: 3 November 30, 2019
EN

Investigation of The Effect of Intermediate Dose Calculation Module on Dose Dıstrıbutıon in Lung Cancer Radiotherapy Patients

Abstract

The aim of this study was to investigate the effect of the use of intermediate dose calculation module on dose volume histogram (DVH) during dose optimization in the treatment plans of radiotherapy patients diagnosed with lung cancer.

This study was carried out by using Eclipse (Version 15.3) treatment planning system with Trilogy model Linear Accelerator device in Radiation Oncology Department of Şişli Hamidiye Etfal Training and Research Hospital. Ten patients with lung cancer were included in the study. In this study, critical organ doses, conformity index (CI) and homogenity index (HI) were compared by making optimization in cases where intermediate dose calculation module was active and inactive.

The plans using the Intermediate dose calculation model are more homogeneous and uniform. Differences between critical organ doses, conformity index (CI) and homogenity index (HI) were statistically significant when using the Intermediate dose calculation module.

It has been demonstrated that the intermediate dose calculation method in heterogeneous lung cancer patients is superior in terms of dose homogeneity and tumor volume enveloping, which improves the quality of treatment plans.

Keywords

References

  1. [1] S.G. Spiro, J.C. Porter; “Lung cancer-Where are we today? Current advances in staging and nonsurgical treatment” Am J Respir Crit Care Med. 166:1166–1196. (2002).
  2. [2] G.M. Parkin, P. Pisani, J. Ferlay; “Global cancer statistics” CA Cancer J Clin 49:33-6 (1999).
  3. [3] M. Hattori, M. Fujita, Y. Ito, et. al.; “Use of a Population-Based Cancer Registry to Calculate Twenty-Year Trends in Cancer Incidence and Mortality in Fukui Prefecture” J Epidemiol (2010).
  4. [4] P. Pisani, D.M. Parkin, F. Bray, J. Ferlay; Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 83:18-29 (1999).
  5. [5] Sağlık Bakanlığı Kanser İstatistikleri, (2017).
  6. [6] M. Gültekin, H. Bilge, Ş.Ç. Gökçe ş, G. Özyiğit, O.G. Yıldız, Temel Ve Klinik Radyoterapi, 1. Baskı, İzmir, Hürriyet Matbaa, s.239 (2013).
  7. [7] L.J. Machlın, and A. Pendıch; “Free radical tissue damage. protective role of antioxidant nutrients” Faseb Journal 441-445 (1987).
  8. [8] M.S. Hug, Y. Yu, Z.P. Chan, and N. Suntharalıngam “Dosimetrics characteristics of commercial multileaf collimator” Medical Physics 241 – 247(1995).

Details

Primary Language

English

Subjects

Clinical Sciences

Journal Section

Research Article

Publication Date

November 30, 2019

Submission Date

September 30, 2019

Acceptance Date

October 31, 2019

Published in Issue

Year 2019 Volume: 5 Number: 3

APA
Yahşi Çelen, Y., & Kızılkaya, H. O. (2019). Investigation of The Effect of Intermediate Dose Calculation Module on Dose Dıstrıbutıon in Lung Cancer Radiotherapy Patients. International Journal of Computational and Experimental Science and Engineering, 5(3), 142-146. https://doi.org/10.22399/ijcesen.626510