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Simulation of action potential and wake trigger processes in MATLAB environment

Year 2022, Volume: 6 Issue: 1, 29 - 37, 30.03.2022

Abstract

In this study, it is aimed to simulate the action potentials in MATLAB’s Simulink environment. For the simulation carried out, firstly, the electric current of the potential flow in the cell membrane was modelled. Transmission and excitation of Action Potentials were studied in the simulation. The relationship between excitation and conduction timing action potentials is shown.

References

  • 1. Yalcinkaya, F., & Unsal, H. Matlab/Simulink Based Comparative Analysis of the Effect of Ion Concentration on Action Potantial by Using Hodgkin-Huxley and Morris-Lecar Neuron Models. In 2017 21st National Biomedical Engineering Meeting (BIYOMUT) (pp.i-iv). IEEE.
  • 2. Armstrong, C.M. and F. Bezanilla, Charge movement associated with the opening and closing of the activation gates of the Na channels. J Gen Physio, 1974. 63(5): p.533-¬52
  • 3. Ashmore, J.F., Forward and reverse transduction in the mammalian cochlea Neurosci Res Suppl, 1990. 12: p. S39-¬‐50
  • 4. Hodgkin, A. L., & Huxley, A. F. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of physiology, 117(4), 500.
  • 5. Ernst Klett Verlag GmbH, Stuttgart 2018 | www.klett.de | Alle Rechte vorbehalten Von dieser Druckvorlage ist die Vervielfältigung für den eigenen Unterrichtsgebrauch gestattet. Die Kopiergebühren sind abgegolten. Die Entstehung des Aktionspotentials, (Lesson note)
  • 6. Cole, K.S., Mostly membranes (Kenneth S. Cole). Annu Rev Physiol, 1979. 41: p. 1-¬‐24.
  • 7. Hodgkin, A.L. and A.F. Huxley, A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol, 1952. 117(4): p. 500-¬‐44.
  • 8. Nether, E. and B. Salman, Single-¬channel currents recorded from membrane of denervated frog muscle fibres. Nature, 1976. 260(5554): p. 799-¬‐802.
  • 9. Santos-¬Sachi, J., S. Kakheti, and Stochastic, Effects of membrane potential on the voltage dependence of motility related charge in outer hair cells of the guineapig. J. Physiol, 1998. 510 (Pt 1): p. 225-¬‐35
  • 10. Santos-¬‐Sachi, J., Reversible inhibition of voltage-¬dependent outer hair cell motility and capacitance. J Neurosci, 1991. 11(10): p. 3096-¬‐110.
  • 11. Physics-Praktikum for students of medicine (Lesson note)
  • 12. Engelhardt, Breves, Physiology of Pets, Enke Verlag 2005.
  • 13. Van Schaik, A. (2001). Building blocks for electronic spiking neural networks. Neural networks, 14(6-7), 617-628.
  • 14. Tahayori, B., & Dokos, S. (2012). Optimal stimulus current waveshape for a Hodgkin-Huxley model neuron. In 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (pp. 4627-4630). IEEE.
  • 15. Kirigeeganage, S., Jackson, D., Zurada, J. M., & Naber, J. (2018, December). Modeling the bursting behavior of the Hodgkin-Huxley neurons using genetic algorithm-based parameter search. In 2018 IEEE International Symposium on Signal Processing and Information Technology (ISSPIT) (pp. 470-475). IEEE.
  • 16. Beken, M., Gunhan, H.M., Akbulut, E., Çapraz, T. “Climate Control System for Cold Storage Depots”, International Journal of Engineering Science and Application, Vol. 1, No, 2, 2017.
Year 2022, Volume: 6 Issue: 1, 29 - 37, 30.03.2022

Abstract

Supporting Institution

Nişantaşı Üniversitesi BAP

References

  • 1. Yalcinkaya, F., & Unsal, H. Matlab/Simulink Based Comparative Analysis of the Effect of Ion Concentration on Action Potantial by Using Hodgkin-Huxley and Morris-Lecar Neuron Models. In 2017 21st National Biomedical Engineering Meeting (BIYOMUT) (pp.i-iv). IEEE.
  • 2. Armstrong, C.M. and F. Bezanilla, Charge movement associated with the opening and closing of the activation gates of the Na channels. J Gen Physio, 1974. 63(5): p.533-¬52
  • 3. Ashmore, J.F., Forward and reverse transduction in the mammalian cochlea Neurosci Res Suppl, 1990. 12: p. S39-¬‐50
  • 4. Hodgkin, A. L., & Huxley, A. F. (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of physiology, 117(4), 500.
  • 5. Ernst Klett Verlag GmbH, Stuttgart 2018 | www.klett.de | Alle Rechte vorbehalten Von dieser Druckvorlage ist die Vervielfältigung für den eigenen Unterrichtsgebrauch gestattet. Die Kopiergebühren sind abgegolten. Die Entstehung des Aktionspotentials, (Lesson note)
  • 6. Cole, K.S., Mostly membranes (Kenneth S. Cole). Annu Rev Physiol, 1979. 41: p. 1-¬‐24.
  • 7. Hodgkin, A.L. and A.F. Huxley, A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol, 1952. 117(4): p. 500-¬‐44.
  • 8. Nether, E. and B. Salman, Single-¬channel currents recorded from membrane of denervated frog muscle fibres. Nature, 1976. 260(5554): p. 799-¬‐802.
  • 9. Santos-¬Sachi, J., S. Kakheti, and Stochastic, Effects of membrane potential on the voltage dependence of motility related charge in outer hair cells of the guineapig. J. Physiol, 1998. 510 (Pt 1): p. 225-¬‐35
  • 10. Santos-¬‐Sachi, J., Reversible inhibition of voltage-¬dependent outer hair cell motility and capacitance. J Neurosci, 1991. 11(10): p. 3096-¬‐110.
  • 11. Physics-Praktikum for students of medicine (Lesson note)
  • 12. Engelhardt, Breves, Physiology of Pets, Enke Verlag 2005.
  • 13. Van Schaik, A. (2001). Building blocks for electronic spiking neural networks. Neural networks, 14(6-7), 617-628.
  • 14. Tahayori, B., & Dokos, S. (2012). Optimal stimulus current waveshape for a Hodgkin-Huxley model neuron. In 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (pp. 4627-4630). IEEE.
  • 15. Kirigeeganage, S., Jackson, D., Zurada, J. M., & Naber, J. (2018, December). Modeling the bursting behavior of the Hodgkin-Huxley neurons using genetic algorithm-based parameter search. In 2018 IEEE International Symposium on Signal Processing and Information Technology (ISSPIT) (pp. 470-475). IEEE.
  • 16. Beken, M., Gunhan, H.M., Akbulut, E., Çapraz, T. “Climate Control System for Cold Storage Depots”, International Journal of Engineering Science and Application, Vol. 1, No, 2, 2017.
There are 16 citations in total.

Details

Primary Language English
Subjects Engineering
Journal Section Articles
Authors

Murat Beken 0000-0001-9995-1321

Önder Eyecioglu 0000-0002-9735-5697

Batuhan Hangün 0000-0002-0271-6868

Nursaç Kurt 0000-0002-9338-0174

Publication Date March 30, 2022
Published in Issue Year 2022 Volume: 6 Issue: 1

Cite

IEEE M. Beken, Ö. Eyecioglu, B. Hangün, and N. Kurt, “Simulation of action potential and wake trigger processes in MATLAB environment”, IJESA, vol. 6, no. 1, pp. 29–37, 2022.

ISSN 2548-1185
e-ISSN 2587-2176
Period: Quarterly
Founded: 2016
Publisher: Nisantasi University
e-mail:ilhcol@gmail.com