Abstract
The study was aimed to determine the antimicrobial activity of Azadirachtaindica seed oil against some disease-causing organism such as Staphylococcus aureus, Salmonella typhi and Pseudomonas aeruginosa. This study of antibacterial activity against selected pathogens was done by dilution method, agar disc diffusion method and agar well diffusion method. Pathogens were taken from General Hospital Mubi. The locally extracted oil tested showed antibacterial activity against all the three (3) pathogenic bacteria even at very low concentration. In case of two (2) of the pathogens (Staphylococcus aureus and Pseudomonas aeruginosa), inhibition of growth caused by Azadirachta indica oil was 99.99%. The results showed that the oil will be an honest source of antibacterial agents. The encouraging observation also indicate that this oil should be exploited as natural antibiotic for the treatment of several infectious diseases caused by these pathogens and could be useful in understanding the relations between traditional cures and current medicines.
References
- 1. Perrone, G.G., K.D. Barrow, and I.J. McFarlane, The selective enzymatic synthesis of lipophilic esters of swainsonine. Bioorganic & Medicinal Chemistry, 1999. 7: p. 831-835. 2. Ozyilmaz, G. and E. Yağız, Isoamylacetate production by entrapped and covalently bound Candida rugosa and porcine pancreatic lipases. Food Chemistry, 2012. 135(4): p. 2326-2332. Doi:10.1016/j.foodchem.2012.07.062 3. Ozyilmaz, G. and E. Yağiz, Comparison of the performance of entrapped and covalently immobilized lipases in the synthesis of pear flavor ester. Turkish Journal of Biochemistry, 2017. 42(3): p. 339-347. Doi:10.1515/tjb-2016-0110 4. Al-Zuhair, S., et al., The effect of fatty acid concentration and water content on the production of biodiesel by lipase. Biochemical Engineering Journal, 2006. 30: p. 212-217. Doi:10.1016/j.bej.2006.04.007
Abstract
The study was aimed to determine the antimicrobial activity of Azadirachtaindica seed oil against some disease-causing organism such as Staphylococcus aureus, Salmonella typhi and Pseudomonas aeruginosa. This study of antibacterial activity against selected pathogens was done by dilution method, agar disc diffusion method and agar well diffusion method. Pathogens were taken from General Hospital Mubi. The locally extracted oil tested showed antibacterial activity against all the three (3) pathogenic bacteria even at very low concentration. In case of two (2) of the pathogens (Staphylococcus aureus and Pseudomonas aeruginosa), inhibition of growth caused by Azadirachta indica oil was 99.99%. The results showed that the oil will be an honest source of antibacterial agents. The encouraging observation also indicate that this oil should be exploited as natural antibiotic for the treatment of several infectious diseases caused by these pathogens and could be useful in understanding the relations between traditional cures and current medicines.
References
- 1. Perrone, G.G., K.D. Barrow, and I.J. McFarlane, The selective enzymatic synthesis of lipophilic esters of swainsonine. Bioorganic & Medicinal Chemistry, 1999. 7: p. 831-835. 2. Ozyilmaz, G. and E. Yağız, Isoamylacetate production by entrapped and covalently bound Candida rugosa and porcine pancreatic lipases. Food Chemistry, 2012. 135(4): p. 2326-2332. Doi:10.1016/j.foodchem.2012.07.062 3. Ozyilmaz, G. and E. Yağiz, Comparison of the performance of entrapped and covalently immobilized lipases in the synthesis of pear flavor ester. Turkish Journal of Biochemistry, 2017. 42(3): p. 339-347. Doi:10.1515/tjb-2016-0110 4. Al-Zuhair, S., et al., The effect of fatty acid concentration and water content on the production of biodiesel by lipase. Biochemical Engineering Journal, 2006. 30: p. 212-217. Doi:10.1016/j.bej.2006.04.007
Details
| Primary Language | English |
|---|---|
| Subjects | Microbiology (Other) |
| Journal Section | Research Article |
| Authors | |
| Submission Date | June 26, 2025 |
| Acceptance Date | January 12, 2026 |
| Publication Date | April 16, 2026 |
| IZ | https://izlik.org/JA89ZU95JT |
| Published in Issue | Year 2026 Volume: 9 Issue: 1 |