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Potential Human Health Risk from Toxic/Carcinogenic Arsenic in Ripe and Unripe Tomatoes Grown in Wastewater Exposed Zone

Year 2024, Volume: 10 Issue: 1, 89 - 99, 30.06.2024
https://doi.org/10.29132/ijpas.1430284

Abstract

The aim of the present study was to investigate the potential risk to human health from toxic/carcinogenic arsenic in ripe (RiTo) and unripe tomatoes (UnRiTo) grown in the municipal wastewater treatment plant effluents exposure zone. The arsenic concen-trations were determined in each tissue of RiTo and UnRiTo tomatoes. Arsenic values in tomatoes were root>leaf>unripe tomato>ripe tomato>stem. The maximum ED (exposure dose) value in RiTos was 1.21E-02 mg.kg-1.day-1 for child, minimum ED value was 4.80E-03 mg.kg-1.day-1 for male. The ED value was calculated as 5.44E-03 mg.kg-1.day-1 for female. The maximum ED value in UnRiTo was 2.12E-02 mg.kg-1.day-1 for child, min ED value was 8.39-03 mg.kg-1.day-1 for male. ED value was calculated as 9.51E-03 mg.kg-1.day-1 for female. EDs in RiTo and UnRiTo were child>female>male. When the HQs (hazard quotient) in RiTo and UnRiTo compared, HQ values in UnRiTo were higher. All of the HQ values were higher than 1. As a re-sult, results of tomatoes analysis show that there was non-carcinogenic and carcino-genic health risks.

References

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  • Anandkumar, A., Li, J., Prabakaran, K., Jia, Z.X., Du, D. (2020). Accumulation of toxic elements in an invasive crayfish species (Procambarus clarkii) and its health risk assessment to humans, Journal of Food Composition and Analysis, 88: Article 103449.
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  • Edokpayi, J., Odiyo, J., Msagati, T., Popoola, E. (2015). Removal efficiency of faecal indicator organisms, nutrients and heavy metals from a peri-urban wastewater treatment plant in thohoyandou, Limpopo Province, South Africa, Int. J. Environ. Res. Public Health, 12: 7300-7320.
  • Mosolloane, P.M., Bredenhand, E., Otomo, P.V. (2019). Laboratory assessment of the ecotoxic effects of sewage sludge from the Maluti-Drakensberg region on a terrestrial oligochaete species, Ecotoxicology, 28:86-91.
  • Sun, Z., Hu, Y., Cheng, H. (2020). Public health risk of toxic metal(loid) pollution to the population living near an abandoned small-scale polymetallic mine, Science of The Total Environment, 718:Article 137434.
  • Hough, R.L., Breward, N., Young, S.D., Crout, N.M.J., Tye, A.M., Moir, A.M., Thornton, I. (2004). Assessing potential risk of heavy metal exposure from consumption of home-produced vegetables by urban populations, Environ. Health Persp., 112: 215-221.
  • Nachman, K.E., Punshon, T., Rardin, L., Signes-Pastor, A.J., Murray, C.J., Karagas, M.R. 2018. Opportunities and challenges for dietary arsenic intervention, Environ. Health Persp., 126: Article 084503.
  • Cui, D., Zhang, P., Li, H., Zhang, Z., Yang, Z. (2020). Biotransformation of dietary inorganic arsenic in a freshwater fish Carassius auratus and the unique association between arsenic dimethylation and oxidative damage, Journal of Hazardous Materials, 391: Article 122153.
  • Zhao, Y., Zhen, Z., Wang, Z., Zeng, L., Yan, C. (2020). Influence of environmental factors on arsenic accumulation and biotransformation using the aquatic plant species Hydrilla verticillata, Journal of Environmental Sciences, 90: 244-252.
  • Bocca, B., Pino, A., Brumatti, L. V., Rosolen, V., Ronfani, L. (2020). Children exposure to inorganic and organic arsenic metabolites: A cohort study in Northeast Italy, Environmental Pollution, 265: 114826.
  • Lyu, R., Gao, Z., Li, D., Yang, Z., Zhang, T. (2020). Bioaccessibility of arsenic from gastropod along the Xiangjiang River: Assessing human health risks using an in vitro digestion model, Ecotox-icology and Environmental Safety, 193: Article 110334.
  • Manthari, R.K., Tikka, C., Ommati, M.M., Niu, R., Sun, Z., Wang, J. (2018). Arsenic-induced autophagy in the developing mouse cerebellum: involvement of the blood-brain barrier’s tight-junction proteins and the PI3K-Akt-mTOR signaling pathway, J. Agric. Food Chem., 66: 8602-8614.
  • Signes-Pastor, A.J., Mitra, K., Sarkhel, S., Hobbes, M., Burlo, F., de Groot,W.T. (2008). Arsenic speciation in food and estimation of the dietary intake of inorganic arsenic in a rural village of West Bengal, India, J. Agric. Food Chem., 56:9469-9474.
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  • Topal, M. , Aşcı Toraman, Z. , Arslan Topal, E. I. , Sel, C. & Öbek, E. (2021). Investigation of SARS-CoV-2 and gastrointestinal pathogens in a municipal wastewater treatment plant in Turkey . International Journal of Pure and Applied Sciences , 7 (3) , 500-508 . DOI: 10.29132/ijpas.956919.
  • Topal, M., Arslan Topal, E.I., (2011). Evaluation of the Elazığ municipal wastewater treatment plant with some parameters in 2010-2011 Winter season, Cumhur. Sci. J., 32: 1-12.
  • Topal, M., Uslu, G., Öbek, E., Arslan Topal, E.I., (2014). Evaluation of Elazığ municipal wastewater treatment plant with physicochemical parameters, Eurasia 2014 Waste Management Symposium, p.1169–1176, İstanbul, Turkey.
  • Topal, M., Uslu, G., Öbek, E., Arslan Topal, E.I., (2016). Investigation of relationships between removals of tetracycline and degradation products and physicochemical parameters in municipal wastewater treatment plant, Journal of Environmental Management, 173:1-9.
  • Lenntech, “Chemical properties of arsenic - Health effects of arsenic - Environmental effects of arsenic” [online document], (2023). Available: https://www.lenntech.com/periodic/elements/as.htm [Accessed: Sep 14, 2023].
  • Lian, M.; Wang, J.; Sun, L.; Xu, Z.; Tang, J.; Yan, J.; Zeng, X. (2019). Profiles and potential health risks of heavy metals in soil and crops from the watershed of Xi River in Northeast China. Ecotoxicol. Environ.Saf., 169, 442-448.
  • USEPA. (2001). Supplemental Guidance for Developing Soil Screening Levels for Superfund Sites [R]. Office of Solid Waste and Emergency Response, Washington, DC [OSWER9355.4e24].
  • USEPA. (2011). United States Environmental Protection Agency. Exposure Factors Handbook. National Center for Environmental Assessment. Washington, DC (EPA/600/R-09/ 052F), https://cfpub.epa.gov/ncea/risk/recordisplay.cfm?deid=236252.
  • USEPA. (1989). Risk assessment guidance for Superfund Human health evaluation manual, (part A) [R], vol. 1, Office of emergency and remedial response, Washington, DC (1989) [EPA/540/1-89/002].
  • Markert, B. (1992). Establishing of Reference Plant for Inorganic Characterization of Different Plant Species By Chemical Fingerprinting. Water Air Soil Pollut. 64:533-538.
  • Bhattacharya, P., Welch, A.H., Stollenwerk, K.G., McLaughlin, M.J., Bundschuh, J., Panaullah, G. (2007). Arsenic in the environment: biology and chemistry, Science of the Total Environment, 379:109-120.
  • Naveed, S., Yu, Q., Zhang, C., Ge, Y., (2020). Extracellular polymeric substances alter cell surface properties, toxicity, and accumulation of arsenic in Synechocystis PCC6803, Environmental Pollution, 261:Article 114233.
  • Zuzolo, D., Cicchella, D., Demetriades, A., Birke, M. (2020). Arsenic: Geochemical distribution and age-related health risk in Italy, Environmental Research, 182:Article 109076.
  • Hsueh, Y.M., Chen, W.J., Lee, C.Y., Chien, S.N., Shiue, H.S., Huang, S.R. (2016). Association of arsenic methylation capacity with developmental delays and health status in children: a prospective case–control trial, Sci. Rep., 6: 37287.

Year 2024, Volume: 10 Issue: 1, 89 - 99, 30.06.2024
https://doi.org/10.29132/ijpas.1430284

Abstract

References

  • Gunawardena, S.A., Gunawardana, J.W., Chandrajith, R., Thoradeniya, T., Jayasinghe, S. (2020). Renal bioaccumulation of trace elements in urban and rural Sri Lankan populations: A preliminary study based on post mortem tissue analysis, Journal of Trace Elements in Medicine and Biology, 61: Article 126565.
  • Anandkumar, A., Li, J., Prabakaran, K., Jia, Z.X., Du, D. (2020). Accumulation of toxic elements in an invasive crayfish species (Procambarus clarkii) and its health risk assessment to humans, Journal of Food Composition and Analysis, 88: Article 103449.
  • USEPA, (2004). U.S.E.P.A, Primer for Municipal Wastewater Treatment Systems, US Environ-mental Protection Agency Municipal Support, Division Office.
  • Moloi, M., Ogbeide, O., Otomo, P.V. (2020). Probabilistic health risk assessment of heavy metals at wastewater discharge points within the Vaal River Basin, South Africa, International Journal of Hygiene and Environmental Health, 224:Article 113421.
  • Edokpayi, J., Odiyo, J., Msagati, T., Popoola, E. (2015). Removal efficiency of faecal indicator organisms, nutrients and heavy metals from a peri-urban wastewater treatment plant in thohoyandou, Limpopo Province, South Africa, Int. J. Environ. Res. Public Health, 12: 7300-7320.
  • Mosolloane, P.M., Bredenhand, E., Otomo, P.V. (2019). Laboratory assessment of the ecotoxic effects of sewage sludge from the Maluti-Drakensberg region on a terrestrial oligochaete species, Ecotoxicology, 28:86-91.
  • Sun, Z., Hu, Y., Cheng, H. (2020). Public health risk of toxic metal(loid) pollution to the population living near an abandoned small-scale polymetallic mine, Science of The Total Environment, 718:Article 137434.
  • Hough, R.L., Breward, N., Young, S.D., Crout, N.M.J., Tye, A.M., Moir, A.M., Thornton, I. (2004). Assessing potential risk of heavy metal exposure from consumption of home-produced vegetables by urban populations, Environ. Health Persp., 112: 215-221.
  • Nachman, K.E., Punshon, T., Rardin, L., Signes-Pastor, A.J., Murray, C.J., Karagas, M.R. 2018. Opportunities and challenges for dietary arsenic intervention, Environ. Health Persp., 126: Article 084503.
  • Cui, D., Zhang, P., Li, H., Zhang, Z., Yang, Z. (2020). Biotransformation of dietary inorganic arsenic in a freshwater fish Carassius auratus and the unique association between arsenic dimethylation and oxidative damage, Journal of Hazardous Materials, 391: Article 122153.
  • Zhao, Y., Zhen, Z., Wang, Z., Zeng, L., Yan, C. (2020). Influence of environmental factors on arsenic accumulation and biotransformation using the aquatic plant species Hydrilla verticillata, Journal of Environmental Sciences, 90: 244-252.
  • Bocca, B., Pino, A., Brumatti, L. V., Rosolen, V., Ronfani, L. (2020). Children exposure to inorganic and organic arsenic metabolites: A cohort study in Northeast Italy, Environmental Pollution, 265: 114826.
  • Lyu, R., Gao, Z., Li, D., Yang, Z., Zhang, T. (2020). Bioaccessibility of arsenic from gastropod along the Xiangjiang River: Assessing human health risks using an in vitro digestion model, Ecotox-icology and Environmental Safety, 193: Article 110334.
  • Manthari, R.K., Tikka, C., Ommati, M.M., Niu, R., Sun, Z., Wang, J. (2018). Arsenic-induced autophagy in the developing mouse cerebellum: involvement of the blood-brain barrier’s tight-junction proteins and the PI3K-Akt-mTOR signaling pathway, J. Agric. Food Chem., 66: 8602-8614.
  • Signes-Pastor, A.J., Mitra, K., Sarkhel, S., Hobbes, M., Burlo, F., de Groot,W.T. (2008). Arsenic speciation in food and estimation of the dietary intake of inorganic arsenic in a rural village of West Bengal, India, J. Agric. Food Chem., 56:9469-9474.
  • TMAF, (2023). https://arastirma.tarimorman.gov.tr/tepge/Belgeler/PDF%20Tar%C4%B1m%20%C3%9Cr%C3%BCnleri%20Piyasalar%C4%B1/2023-Temmuz%20Tar%C4%B1m%20%C3%9Cr%C3%BCnleri%20Raporu/DOMATES%20T%C3%9CP%20HAZ%C4%B0RAN%202023-TEPGE.pdf.
  • TUİK, (2020). Turkish Statistical Institute, 2020. https://www.tuik.gov.tr/ Acessed: 10.11.2020.
  • Topal, M. , Aşcı Toraman, Z. , Arslan Topal, E. I. , Sel, C. & Öbek, E. (2021). Investigation of SARS-CoV-2 and gastrointestinal pathogens in a municipal wastewater treatment plant in Turkey . International Journal of Pure and Applied Sciences , 7 (3) , 500-508 . DOI: 10.29132/ijpas.956919.
  • Topal, M., Arslan Topal, E.I., (2011). Evaluation of the Elazığ municipal wastewater treatment plant with some parameters in 2010-2011 Winter season, Cumhur. Sci. J., 32: 1-12.
  • Topal, M., Uslu, G., Öbek, E., Arslan Topal, E.I., (2014). Evaluation of Elazığ municipal wastewater treatment plant with physicochemical parameters, Eurasia 2014 Waste Management Symposium, p.1169–1176, İstanbul, Turkey.
  • Topal, M., Uslu, G., Öbek, E., Arslan Topal, E.I., (2016). Investigation of relationships between removals of tetracycline and degradation products and physicochemical parameters in municipal wastewater treatment plant, Journal of Environmental Management, 173:1-9.
  • Lenntech, “Chemical properties of arsenic - Health effects of arsenic - Environmental effects of arsenic” [online document], (2023). Available: https://www.lenntech.com/periodic/elements/as.htm [Accessed: Sep 14, 2023].
  • Lian, M.; Wang, J.; Sun, L.; Xu, Z.; Tang, J.; Yan, J.; Zeng, X. (2019). Profiles and potential health risks of heavy metals in soil and crops from the watershed of Xi River in Northeast China. Ecotoxicol. Environ.Saf., 169, 442-448.
  • USEPA. (2001). Supplemental Guidance for Developing Soil Screening Levels for Superfund Sites [R]. Office of Solid Waste and Emergency Response, Washington, DC [OSWER9355.4e24].
  • USEPA. (2011). United States Environmental Protection Agency. Exposure Factors Handbook. National Center for Environmental Assessment. Washington, DC (EPA/600/R-09/ 052F), https://cfpub.epa.gov/ncea/risk/recordisplay.cfm?deid=236252.
  • USEPA. (1989). Risk assessment guidance for Superfund Human health evaluation manual, (part A) [R], vol. 1, Office of emergency and remedial response, Washington, DC (1989) [EPA/540/1-89/002].
  • Markert, B. (1992). Establishing of Reference Plant for Inorganic Characterization of Different Plant Species By Chemical Fingerprinting. Water Air Soil Pollut. 64:533-538.
  • Bhattacharya, P., Welch, A.H., Stollenwerk, K.G., McLaughlin, M.J., Bundschuh, J., Panaullah, G. (2007). Arsenic in the environment: biology and chemistry, Science of the Total Environment, 379:109-120.
  • Naveed, S., Yu, Q., Zhang, C., Ge, Y., (2020). Extracellular polymeric substances alter cell surface properties, toxicity, and accumulation of arsenic in Synechocystis PCC6803, Environmental Pollution, 261:Article 114233.
  • Zuzolo, D., Cicchella, D., Demetriades, A., Birke, M. (2020). Arsenic: Geochemical distribution and age-related health risk in Italy, Environmental Research, 182:Article 109076.
  • Hsueh, Y.M., Chen, W.J., Lee, C.Y., Chien, S.N., Shiue, H.S., Huang, S.R. (2016). Association of arsenic methylation capacity with developmental delays and health status in children: a prospective case–control trial, Sci. Rep., 6: 37287.
There are 31 citations in total.

Details

Primary Language English
Subjects Health and Ecological Risk Assessment
Journal Section Research Article
Authors

Murat Topal 0000-0003-0222-5409

Emine Işıl Arslan Topal 0000-0003-0309-7787

Erdal Öbek 0000-0002-4595-572X

Submission Date February 1, 2024
Acceptance Date June 7, 2024
Early Pub Date June 28, 2024
Publication Date June 30, 2024
Published in Issue Year 2024 Volume: 10 Issue: 1

Cite

APA Topal, M., Arslan Topal, E. I., & Öbek, E. (2024). Potential Human Health Risk from Toxic/Carcinogenic Arsenic in Ripe and Unripe Tomatoes Grown in Wastewater Exposed Zone. International Journal of Pure and Applied Sciences, 10(1), 89-99. https://doi.org/10.29132/ijpas.1430284
AMA Topal M, Arslan Topal EI, Öbek E. Potential Human Health Risk from Toxic/Carcinogenic Arsenic in Ripe and Unripe Tomatoes Grown in Wastewater Exposed Zone. International Journal of Pure and Applied Sciences. June 2024;10(1):89-99. doi:10.29132/ijpas.1430284
Chicago Topal, Murat, Emine Işıl Arslan Topal, and Erdal Öbek. “Potential Human Health Risk from Toxic Carcinogenic Arsenic in Ripe and Unripe Tomatoes Grown in Wastewater Exposed Zone”. International Journal of Pure and Applied Sciences 10, no. 1 (June 2024): 89-99. https://doi.org/10.29132/ijpas.1430284.
EndNote Topal M, Arslan Topal EI, Öbek E (June 1, 2024) Potential Human Health Risk from Toxic/Carcinogenic Arsenic in Ripe and Unripe Tomatoes Grown in Wastewater Exposed Zone. International Journal of Pure and Applied Sciences 10 1 89–99.
IEEE M. Topal, E. I. Arslan Topal, and E. Öbek, “Potential Human Health Risk from Toxic/Carcinogenic Arsenic in Ripe and Unripe Tomatoes Grown in Wastewater Exposed Zone”, International Journal of Pure and Applied Sciences, vol. 10, no. 1, pp. 89–99, 2024, doi: 10.29132/ijpas.1430284.
ISNAD Topal, Murat et al. “Potential Human Health Risk from Toxic Carcinogenic Arsenic in Ripe and Unripe Tomatoes Grown in Wastewater Exposed Zone”. International Journal of Pure and Applied Sciences 10/1 (June2024), 89-99. https://doi.org/10.29132/ijpas.1430284.
JAMA Topal M, Arslan Topal EI, Öbek E. Potential Human Health Risk from Toxic/Carcinogenic Arsenic in Ripe and Unripe Tomatoes Grown in Wastewater Exposed Zone. International Journal of Pure and Applied Sciences. 2024;10:89–99.
MLA Topal, Murat et al. “Potential Human Health Risk from Toxic Carcinogenic Arsenic in Ripe and Unripe Tomatoes Grown in Wastewater Exposed Zone”. International Journal of Pure and Applied Sciences, vol. 10, no. 1, 2024, pp. 89-99, doi:10.29132/ijpas.1430284.
Vancouver Topal M, Arslan Topal EI, Öbek E. Potential Human Health Risk from Toxic/Carcinogenic Arsenic in Ripe and Unripe Tomatoes Grown in Wastewater Exposed Zone. International Journal of Pure and Applied Sciences. 2024;10(1):89-9.

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