Research Article
BibTex RIS Cite

Van İlinin Merkez İlçelerinde Kuaför Çalışanlarında Bazı Antioksidan Enzim Düzeylerinin Belirlenmesi

Year 2022, , 918 - 929, 14.11.2022
https://doi.org/10.33715/inonusaglik.1066596

Abstract

Kuaförlük tehlikeli bir meslek olmasa da kuaförlerin alerjenler, kanserojenler veya organik solventler olarak bilinen kimyasal kombinasyonlara maruz kaldıkları bilinmektedir. Bu çalışmada, Van'daki kuaför çalışanlarında bazı önemli antioksidanlar olarak bilinen süperoksit dismutaz (SOD), katalaz (CAT) ve glutatyon (GSH) ile lipid peroksidasyonunun son ürünü ve oksidatif stres düzeyinin göstergesi olan malondialdehit (MDA) düzeylerinin belirlenmesi amaçlanmıştır. Araştırma kapsamına Van ili merkez ilçelerinde (Edremit, Tusba ve İpekyolu) çalışan 33 kadın kuaför çalışanı denek olarak, kuaför hizmetlerinden faydalanan gönüllü katılımcılar kontrol grubu olarak dahil edildi. Çalışmayı kabul edenlerden venöz kan alındı, laboratuvarda incelendi ve sonuçları istatistiksel olarak analiz edildi. MDA, CAT, SOD ve GSH için grup ortalamaları arasındaki fark istatistiksel olarak anlamlıydı (p<0.05). Sonuç olarak mesleki yaşamları uzun yıllar sürecek olan kuaförlerin, sürekli fiziksel ve kimyasal etkenlere maruz kaldıkları için egzama, astım, kalp-damar hastalıkları, kanser gibi reaktif oksijen türevlerinin de bulunduğu hastalıkların oluşumunda potansiyel risk grubunda olduğu söylenebilir.

References

  • Aebi, H. (1974). Catalase In Methods of enzymatic analysis. Academic Press, 1, 673-684. doi:http://doi.org/10.1016/b978-0-12-091302-2.50032-3
  • Akkuş, İ. (1995). Serbest radikaller ve fizyopatolojik etkileri. Konya: Mimoza Yayınları.
  • Altınışık, M., A. D, A. T. F. B. (2000). Serbest oksijen radikalleri ve antioksidanlar. ADÜ Tıp Fakültesi, Biyokimya AD. Aydın. https://www.mustafaaltinisik.org.uk/21-adsem-01s.pdf
  • Beutler, E. (1963). Improved method for the determination of blood glutathione. J Lab Clin Med, 61, 882-888. https://pubmed.ncbi.nlm.nih.gov/13967893/
  • Bjarte, D. K. (2005). Tobacco Control. 14, 305–32. [Google Scholar].
  • Bolt, H. M. & Golka, K. (2007). The debate on carcinogenicity of permanent hair dyes: new insights, Crit Rev Toxicol, 37, 521–536.
  • Czene, K., Tiikkaja, S. & Hemminki. K. (2003). Cancer risks in hairdressers: assessment of carcinogenicity of hair dyes and gels. Int J Cancer, 105, 108–112.
  • Çetin, E., Çetin, N. & Küçük, O. (2011). Toklularda karayolu ile taşımanın oksidan-antioksidan sistem üzerine etkisi. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 6, 103-109.
  • Çömelekoğlu, Ü., Mazmancı, B. & Arpacı, A. (2000). Pestisidlerin Kronik etkisine maruz kalan tarım işçilerinde eritrosit süperoksit dismutaz ve katalaz aktiviteleri. Turk J Biol, 24, 483-488. https://app.trdizin.gov.tr/publication/paper/detail/TVRjMU16ZzQ
  • Dryson, E., ’t Mannetje, A., Walls, C., McLean, D., McKenzie, F., Maule, M., Cheng, S., Cunningham, C., Kromhout, H., Boffetta, P., Blair, A. & Pearce, N. (2007). Case-control study of high risk occupations for bladder cancer in New Zealand. Int J Cancer, 15, 1340–1346.
  • Eloff, F. C., Preston, R., Pretorius, P. J., Du Plessis, J. L., Laubscher, P. J., Van Aarde, M. N., Van der Westhuizen, F. H. & Franken, A. (2013). DNA damage and repair capacity in hairdressers exposed to chemical products: a pilot study. Occupational Health Southern Africa, 19(6), 6-13. https://hdl.handle.net/10520/EJC145076
  • Ferrari, M., Moscato, G. & Imbriani, M. (2005). Allergic cutaneous diseases in hairdressers. Med Lav, 96, 102-118.
  • Golka, K., Wiese, A., Assennato, G. & Boltet, H. M. (2004). Occupational exposure and urological cancer. World J Urol, 21, 382–91.
  • Gutteridge, J. M. (1995). Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clinical Chemistry, 41(12), 1819-1828. doi: https://doi.org/10.1093/clinchem/41.12.1819
  • Gündüz, A. M. & Demir, C. (2020). Evaluation of oxidative stress in angiography workers. Annals of Medical Research, 27(9), 2382-5. doi: https://doi.org/10.5455/annalsmedres.2020.04.410
  • Hamanaka, H., Miyachi, Y. & Imamura, S. (1990). Photoprotective effect of topically applied superoxide dismutase on sunburn reaction in comparison with sunscreen. J Dermatol, 17(10), 595-598.
  • Harling, M., Schablon, A., Schedlbauer, G., Dulon, M. & Nienhaus, A. (2010). Bladder cancer among hairdressers: A meta-analysis. Occup Environ Med. 67, 351–358.[PMC free article] [PubMed] [Google Scholar]
  • Heikkinen, S., Pitkäniemi, J., Sarkeala, T., Malila, N. & Koskenvuo, M. (2015). Does hair dye use increase the risk of breast cancer? A population-based case-control study of Finnish women. PloS One, 10(8), e0135190.
  • IARC. (1993). Monographs of the evaluation of carcinogenic risk to human. Occupational exposures of hairdressers and barbers and personal use of hair colourants; some hair dyes, cosmetic colourants, industrial dyestuffs and aromatic amines. 57. Lyon, France: World Health Organization, International Agency for Research on Cancer.
  • Karabulut, H. & Gülay, M. Ş. (2016). Antioksidanlar. Veterinary Journal of Mehmet Akif Ersoy University, 1 (1), 65-76. https://dergipark.org.tr/en/download/article-file/227284
  • Lamba, A. B.,Ward, M. H. & Weeks, J. Letal. (2001). Cancermortality patterns among hairdressers and barbers in 24 US states, 1984 to 1995. J Occup Environ Med, 43, 250–258.
  • Leino, T. (1999). Working conditions and health in hairdressing salons. Applied Occupational and Environmental Hygiene, 14(1), 26-33. doi: https://doi.org/10.1080/104732299303386
  • Lind, M. L., Johnsson, S., Lidén, C., Meding, B. & Boman, A. (2015). The influence of hydrogen Peroxide on the permeability of protective gloves to resorcinol in hairdressing. Contact Dermatitis, 72(1), 33-39. https://doi.org/10.1111/cod.12296
  • Lind, M. L., Johnsson, S., Lidén, C., Meding, B. & Boman, A. (2017). Hairdressers' skin exposure to hair dyes during different hair dyeing tasks. Contact Dermatitis, 77(5), 303-310. doi: https://doi.org/10.1111/cod.12833
  • Ma, C. M., Lin, L. Y., Chen, H. W., Huang, L. C., Li, J. F. & Chuang, K. J. (2010). Volatile organic compounds exposure and cardiovascular effects in hair salons. Occupational Medicine, 60(8), 624-630. doi: https://doi.org/10.1093/occmed/kqq128
  • Menicagli, R., Marotta, O. & Menicagli, L. (2018). The question on the potential cancerous effects of hair dyes: The monitoring of the oxidative stress induced by the hair dyes with the dosage of the salivary free radicals. Indian Journal of Occupational and Environmental Medicine, 22(2), 109. Moscato, G. & Galdi, E. (2006). Asthma and hairdressers. Curr Opin Allergy Clin Immunol, 6, 91–95.
  • Picardo, M., Zompetta, C. & Marchese, C. (1992). Paraphenylene diamine, a contact allergen, induces oxidative stress and ICAM-1 expression in human keratinocytes. Br J Dermatol, 126, 450-455.
  • Picardo, M., Zompetta, C., Grandinetti, M., Ameglio, F., Santucci, B., Faggioni, A. & Passi, S. (1996). Paraphenylene diamine, a contact allergen, induces oxidative stress in normal human keratinocytes in culture. Br J Dermatology, 134, 681-685.
  • Pignatti, P., Frossi, B., Pala, G., Negri, S., Oman, H., Perfetti, L., Pucillo, C., Imbriani, M. & Moscato, G. (2013). Oxidative activity of ammonium persulfate salt on mast cells and basophils: Implication in hairdressers’ asthma. International Archives of Allergy and İmmunology, 160(4), 409-419. doi: https://doi.org/10.1159/000343020
  • Preston, R. (2008). Measuring DNA damage and repair as possible biological markers for long- term, low-dose chemical exposure in hairdressers. Doctoral dissertation, North-West University, http://hdl.handle.net/10394/2326
  • Popov, B., Gadjeva, V., Valkanov, P., Popova, S. & Tolekova, A. (2003). Lipid peroxidation, superoxide dismutase and catalase activities in brain tumor tissues. Archives of Physiology and Biochemistry, 111(5), 455-459. doi: https://doi.org/10.3109/13813450312331342328
  • Sim, M. J., Kim, Y. C., Lim, H., Son, I. S., Kwun, I. S. & Kwon, C. S. (2005). The oxidative stress by hair dyeing changes the antioxidant defense systems and strongly relates to the plasma vitamin e concentration. Nutritional Sciences, 8(4), 262-267.
  • Sulaiman, S. H., Demir, H., Soyoral, Y. U. & Demir, C. (2021). Determination of oxidative stress levels and some antioxidant activities in acute and chronic renal failure patients. International Journal of Clinical Chemistry and Laboratory Medicine (IJCCLM), 7(1), 12-19. http://dx.doi.org/10.20431/2455-7153.0701002
  • Şüküroğlu, A. A. & Burgaz, S. (2018). Kuaför salonlarındaki kimyasallara mesleki maruziyet ve sağlık riski. Türk Hijyen ve Deneysel Biyoloji, 75(2), 195-212. doi: https://doi.org/10.5505/TurkHijyen.2018.36539.

DETERMİNATION OF SOME ANTIOXIDANT ENZYME LEVELS IN HAIRDRESSER EMPLOYESS IN THE CENTRAL DISTRICTS OF VAN PROVİNCE

Year 2022, , 918 - 929, 14.11.2022
https://doi.org/10.33715/inonusaglik.1066596

Abstract

Although hairdressing is not a dangerous profession, it is known that hairdressers are exposed to chemical combinations known as allergens, carcinogens or organic solvents. In this study, it was aimed to determine the levels of superoxide dismutase (SOD), catalase (CAT) and glutathione (GSH), which are known as some important antioxidants, and malondialdehyde (MDA), the end product of lipid peroxidation and an indicator of oxidative stress, in hairdresser workers in Van. 33 female hairdresser employees working in the central districts of Van (Edremit, Tusba and Ipekyolu) were included in the scope of the study as subjects, and voluntary participants using hairdresser services were included as the control group. Venous blood was taken from those who accepted the study, examined in the laboratory, and the results were statistically analyzed. The difference between group means for MDA, CAT, SOD and GSH was statistically significant (p<0.05). As a result, it can be said that hairdressers, whose professional lives will last for many years, are in the potential risk group in the formation of diseases such as eczema, asthma, cardiovascular diseases, cancer, in which reactive oxygen derivatives also play a role, since they are constantly exposed to physical and chemical factors.

References

  • Aebi, H. (1974). Catalase In Methods of enzymatic analysis. Academic Press, 1, 673-684. doi:http://doi.org/10.1016/b978-0-12-091302-2.50032-3
  • Akkuş, İ. (1995). Serbest radikaller ve fizyopatolojik etkileri. Konya: Mimoza Yayınları.
  • Altınışık, M., A. D, A. T. F. B. (2000). Serbest oksijen radikalleri ve antioksidanlar. ADÜ Tıp Fakültesi, Biyokimya AD. Aydın. https://www.mustafaaltinisik.org.uk/21-adsem-01s.pdf
  • Beutler, E. (1963). Improved method for the determination of blood glutathione. J Lab Clin Med, 61, 882-888. https://pubmed.ncbi.nlm.nih.gov/13967893/
  • Bjarte, D. K. (2005). Tobacco Control. 14, 305–32. [Google Scholar].
  • Bolt, H. M. & Golka, K. (2007). The debate on carcinogenicity of permanent hair dyes: new insights, Crit Rev Toxicol, 37, 521–536.
  • Czene, K., Tiikkaja, S. & Hemminki. K. (2003). Cancer risks in hairdressers: assessment of carcinogenicity of hair dyes and gels. Int J Cancer, 105, 108–112.
  • Çetin, E., Çetin, N. & Küçük, O. (2011). Toklularda karayolu ile taşımanın oksidan-antioksidan sistem üzerine etkisi. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 6, 103-109.
  • Çömelekoğlu, Ü., Mazmancı, B. & Arpacı, A. (2000). Pestisidlerin Kronik etkisine maruz kalan tarım işçilerinde eritrosit süperoksit dismutaz ve katalaz aktiviteleri. Turk J Biol, 24, 483-488. https://app.trdizin.gov.tr/publication/paper/detail/TVRjMU16ZzQ
  • Dryson, E., ’t Mannetje, A., Walls, C., McLean, D., McKenzie, F., Maule, M., Cheng, S., Cunningham, C., Kromhout, H., Boffetta, P., Blair, A. & Pearce, N. (2007). Case-control study of high risk occupations for bladder cancer in New Zealand. Int J Cancer, 15, 1340–1346.
  • Eloff, F. C., Preston, R., Pretorius, P. J., Du Plessis, J. L., Laubscher, P. J., Van Aarde, M. N., Van der Westhuizen, F. H. & Franken, A. (2013). DNA damage and repair capacity in hairdressers exposed to chemical products: a pilot study. Occupational Health Southern Africa, 19(6), 6-13. https://hdl.handle.net/10520/EJC145076
  • Ferrari, M., Moscato, G. & Imbriani, M. (2005). Allergic cutaneous diseases in hairdressers. Med Lav, 96, 102-118.
  • Golka, K., Wiese, A., Assennato, G. & Boltet, H. M. (2004). Occupational exposure and urological cancer. World J Urol, 21, 382–91.
  • Gutteridge, J. M. (1995). Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clinical Chemistry, 41(12), 1819-1828. doi: https://doi.org/10.1093/clinchem/41.12.1819
  • Gündüz, A. M. & Demir, C. (2020). Evaluation of oxidative stress in angiography workers. Annals of Medical Research, 27(9), 2382-5. doi: https://doi.org/10.5455/annalsmedres.2020.04.410
  • Hamanaka, H., Miyachi, Y. & Imamura, S. (1990). Photoprotective effect of topically applied superoxide dismutase on sunburn reaction in comparison with sunscreen. J Dermatol, 17(10), 595-598.
  • Harling, M., Schablon, A., Schedlbauer, G., Dulon, M. & Nienhaus, A. (2010). Bladder cancer among hairdressers: A meta-analysis. Occup Environ Med. 67, 351–358.[PMC free article] [PubMed] [Google Scholar]
  • Heikkinen, S., Pitkäniemi, J., Sarkeala, T., Malila, N. & Koskenvuo, M. (2015). Does hair dye use increase the risk of breast cancer? A population-based case-control study of Finnish women. PloS One, 10(8), e0135190.
  • IARC. (1993). Monographs of the evaluation of carcinogenic risk to human. Occupational exposures of hairdressers and barbers and personal use of hair colourants; some hair dyes, cosmetic colourants, industrial dyestuffs and aromatic amines. 57. Lyon, France: World Health Organization, International Agency for Research on Cancer.
  • Karabulut, H. & Gülay, M. Ş. (2016). Antioksidanlar. Veterinary Journal of Mehmet Akif Ersoy University, 1 (1), 65-76. https://dergipark.org.tr/en/download/article-file/227284
  • Lamba, A. B.,Ward, M. H. & Weeks, J. Letal. (2001). Cancermortality patterns among hairdressers and barbers in 24 US states, 1984 to 1995. J Occup Environ Med, 43, 250–258.
  • Leino, T. (1999). Working conditions and health in hairdressing salons. Applied Occupational and Environmental Hygiene, 14(1), 26-33. doi: https://doi.org/10.1080/104732299303386
  • Lind, M. L., Johnsson, S., Lidén, C., Meding, B. & Boman, A. (2015). The influence of hydrogen Peroxide on the permeability of protective gloves to resorcinol in hairdressing. Contact Dermatitis, 72(1), 33-39. https://doi.org/10.1111/cod.12296
  • Lind, M. L., Johnsson, S., Lidén, C., Meding, B. & Boman, A. (2017). Hairdressers' skin exposure to hair dyes during different hair dyeing tasks. Contact Dermatitis, 77(5), 303-310. doi: https://doi.org/10.1111/cod.12833
  • Ma, C. M., Lin, L. Y., Chen, H. W., Huang, L. C., Li, J. F. & Chuang, K. J. (2010). Volatile organic compounds exposure and cardiovascular effects in hair salons. Occupational Medicine, 60(8), 624-630. doi: https://doi.org/10.1093/occmed/kqq128
  • Menicagli, R., Marotta, O. & Menicagli, L. (2018). The question on the potential cancerous effects of hair dyes: The monitoring of the oxidative stress induced by the hair dyes with the dosage of the salivary free radicals. Indian Journal of Occupational and Environmental Medicine, 22(2), 109. Moscato, G. & Galdi, E. (2006). Asthma and hairdressers. Curr Opin Allergy Clin Immunol, 6, 91–95.
  • Picardo, M., Zompetta, C. & Marchese, C. (1992). Paraphenylene diamine, a contact allergen, induces oxidative stress and ICAM-1 expression in human keratinocytes. Br J Dermatol, 126, 450-455.
  • Picardo, M., Zompetta, C., Grandinetti, M., Ameglio, F., Santucci, B., Faggioni, A. & Passi, S. (1996). Paraphenylene diamine, a contact allergen, induces oxidative stress in normal human keratinocytes in culture. Br J Dermatology, 134, 681-685.
  • Pignatti, P., Frossi, B., Pala, G., Negri, S., Oman, H., Perfetti, L., Pucillo, C., Imbriani, M. & Moscato, G. (2013). Oxidative activity of ammonium persulfate salt on mast cells and basophils: Implication in hairdressers’ asthma. International Archives of Allergy and İmmunology, 160(4), 409-419. doi: https://doi.org/10.1159/000343020
  • Preston, R. (2008). Measuring DNA damage and repair as possible biological markers for long- term, low-dose chemical exposure in hairdressers. Doctoral dissertation, North-West University, http://hdl.handle.net/10394/2326
  • Popov, B., Gadjeva, V., Valkanov, P., Popova, S. & Tolekova, A. (2003). Lipid peroxidation, superoxide dismutase and catalase activities in brain tumor tissues. Archives of Physiology and Biochemistry, 111(5), 455-459. doi: https://doi.org/10.3109/13813450312331342328
  • Sim, M. J., Kim, Y. C., Lim, H., Son, I. S., Kwun, I. S. & Kwon, C. S. (2005). The oxidative stress by hair dyeing changes the antioxidant defense systems and strongly relates to the plasma vitamin e concentration. Nutritional Sciences, 8(4), 262-267.
  • Sulaiman, S. H., Demir, H., Soyoral, Y. U. & Demir, C. (2021). Determination of oxidative stress levels and some antioxidant activities in acute and chronic renal failure patients. International Journal of Clinical Chemistry and Laboratory Medicine (IJCCLM), 7(1), 12-19. http://dx.doi.org/10.20431/2455-7153.0701002
  • Şüküroğlu, A. A. & Burgaz, S. (2018). Kuaför salonlarındaki kimyasallara mesleki maruziyet ve sağlık riski. Türk Hijyen ve Deneysel Biyoloji, 75(2), 195-212. doi: https://doi.org/10.5505/TurkHijyen.2018.36539.
There are 34 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Araştırma Makalesi
Authors

Halime Yıldız 0000-0002-0603-1815

Canan Demir 0000-0002-4204-9756

Tuğba Gür 0000-0001-7220-0210

Şehriban Yürektürk 0000-0003-4902-0689

Arzu Esen Tekeli 0000-0001-6468-8850

Publication Date November 14, 2022
Submission Date February 1, 2022
Acceptance Date August 4, 2022
Published in Issue Year 2022

Cite

APA Yıldız, H., Demir, C., Gür, T., Yürektürk, Ş., et al. (2022). DETERMİNATION OF SOME ANTIOXIDANT ENZYME LEVELS IN HAIRDRESSER EMPLOYESS IN THE CENTRAL DISTRICTS OF VAN PROVİNCE. İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi, 10(3), 918-929. https://doi.org/10.33715/inonusaglik.1066596