A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and

Muthuvel Arumugam; Thangavel Balasubramanıan; Annain Shanmugam; Hari Garg

EN

A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and

Abstract

Heparin was isolated from two bivalve mollusks such as Tridacna maxima and Perna viridis. The isolated heparin was quantifi ed in crude as well as purifi ed samples and they were estimated as 2.72 & 2.2 gm / kg (crude) and 260 & 248 mg/gm (purifi ed) in T. maxima and P. viridis respectively. Both the bivalves shown the anticoagulant activity of the crude and purifi ed sample 20,128 USP units per kg and 7.4 USP units per mg and 39,000 USP units per kg and 75 USP units per mg and 9,460 USP units per kg and 4.3 USP units per mg and 13,392 USP units per kg and 54 USP units per mg correspondingly in T. maxima and P. viridis. The antiproliferative activity was studied with pulmonary artery smooth muscle cells (PASMC) using RPMI media reported that the result in a dose dependent manner. Among the two clams, P. viridis showed more antiproliferative activity than that of T. maxima

Keywords

antiproliferation, glycosaminoglycans, giant clam, green mussel, heparin

Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Muthuvel Arumugam This is me

Thangavel Balasubramanıan This is me

Annain Shanmugam This is me

Hari Garg This is me

Publication Date

November 1, 2008

Submission Date

November 1, 2008

Acceptance Date

-

Published in Issue

Year 2008 Volume: 2 Number: 3

IZ

https://izlik.org/JA84LK28BT

Cite

RIS / Bibtex

APA

Arumugam, M., Balasubramanıan, T., Shanmugam, A., & Garg, H. (2008). A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and. Journal of Applied Biological Sciences, 2(3), 27-30. https://izlik.org/JA84LK28BT

AMA

1.Arumugam M, Balasubramanıan T, Shanmugam A, Garg H. A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and. J.appl.biol.sci. 2008;2(3):27-30. https://izlik.org/JA84LK28BT

Chicago

Arumugam, Muthuvel, Thangavel Balasubramanıan, Annain Shanmugam, and Hari Garg. 2008. “A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna Maxima (Roeding,1798) and”. Journal of Applied Biological Sciences 2 (3): 27-30. https://izlik.org/JA84LK28BT.

EndNote

Arumugam M, Balasubramanıan T, Shanmugam A, Garg H (November 1, 2008) A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and. Journal of Applied Biological Sciences 2 3 27–30.

IEEE

[1]M. Arumugam, T. Balasubramanıan, A. Shanmugam, and H. Garg, “A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and”, J.appl.biol.sci., vol. 2, no. 3, pp. 27–30, Nov. 2008, [Online]. Available: https://izlik.org/JA84LK28BT

ISNAD

Arumugam, Muthuvel - Balasubramanıan, Thangavel - Shanmugam, Annain - Garg, Hari. “A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna Maxima (Roeding,1798) and”. Journal of Applied Biological Sciences 2/3 (November 1, 2008): 27-30. https://izlik.org/JA84LK28BT.

JAMA

1.Arumugam M, Balasubramanıan T, Shanmugam A, Garg H. A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and. J.appl.biol.sci. 2008;2:27–30.

MLA

Arumugam, Muthuvel, et al. “A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna Maxima (Roeding,1798) and”. Journal of Applied Biological Sciences, vol. 2, no. 3, Nov. 2008, pp. 27-30, https://izlik.org/JA84LK28BT.

Vancouver

1.Muthuvel Arumugam, Thangavel Balasubramanıan, Annain Shanmugam, Hari Garg. A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and. J.appl.biol.sci. [Internet]. 2008 Nov. 1;2(3):27-30. Available from: https://izlik.org/JA84LK28BT