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Year 2008, Volume: 2 Issue: 3, 27 - 30, 01.11.2008

Muthuvel Arumugam Thangavel Balasubramanıan Annain Shanmugam Hari Garg

Abstract

Keywords

antiproliferation glycosaminoglycans giant clam green mussel heparin

A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and

Year 2008, Volume: 2 Issue: 3, 27 - 30, 01.11.2008

Muthuvel Arumugam Thangavel Balasubramanıan Annain Shanmugam Hari Garg

Abstract

Heparin was isolated from two bivalve mollusks such as Tridacna maxima and Perna viridis. The isolated heparin was quantifi ed in crude as well as purifi ed samples and they were estimated as 2.72 & 2.2 gm / kg (crude) and 260 & 248 mg/gm (purifi ed) in T. maxima and P. viridis respectively. Both the bivalves shown the anticoagulant activity of the crude and purifi ed sample 20,128 USP units per kg and 7.4 USP units per mg and 39,000 USP units per kg and 75 USP units per mg and 9,460 USP units per kg and 4.3 USP units per mg and 13,392 USP units per kg and 54 USP units per mg correspondingly in T. maxima and P. viridis. The antiproliferative activity was studied with pulmonary artery smooth muscle cells (PASMC) using RPMI media reported that the result in a dose dependent manner. Among the two clams, P. viridis showed more antiproliferative activity than that of T. maxima

Keywords

antiproliferation glycosaminoglycans giant clam green mussel heparin

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Details

Other ID JA67UY63ZC
Journal Section Research Article
Authors

Muthuvel Arumugam This is me

Thangavel Balasubramanıan This is me

Annain Shanmugam This is me

Hari Garg This is me

Publication Date November 1, 2008
Published in Issue Year 2008 Volume: 2 Issue: 3

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APA Arumugam, M., Balasubramanıan, T., Shanmugam, A., Garg, H. (2008). A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and. Journal of Applied Biological Sciences, 2(3), 27-30.
AMA Arumugam M, Balasubramanıan T, Shanmugam A, Garg H. A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and. J.appl.biol.sci. November 2008;2(3):27-30.
Chicago Arumugam, Muthuvel, Thangavel Balasubramanıan, Annain Shanmugam, and Hari Garg. “A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna Maxima (Roeding,1798) and”. Journal of Applied Biological Sciences 2, no. 3 (November 2008): 27-30.
EndNote Arumugam M, Balasubramanıan T, Shanmugam A, Garg H (November 1, 2008) A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and. Journal of Applied Biological Sciences 2 3 27–30.
IEEE M. Arumugam, T. Balasubramanıan, A. Shanmugam, and H. Garg, “A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and”, J.appl.biol.sci., vol. 2, no. 3, pp. 27–30, 2008.
ISNAD Arumugam, Muthuvel et al. “A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna Maxima (Roeding,1798) and”. Journal of Applied Biological Sciences 2/3 (November 2008), 27-30.
JAMA Arumugam M, Balasubramanıan T, Shanmugam A, Garg H. A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and. J.appl.biol.sci. 2008;2:27–30.
MLA Arumugam, Muthuvel et al. “A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna Maxima (Roeding,1798) and”. Journal of Applied Biological Sciences, vol. 2, no. 3, 2008, pp. 27-30.
Vancouver Arumugam M, Balasubramanıan T, Shanmugam A, Garg H. A Comporative Study of Anticoagulant and Antiproliferative Activity of Fast Moving Heparin From Giant Clam Tridacna maxima (Roeding,1798) and. J.appl.biol.sci. 2008;2(3):27-30.