Biosynthesis of silver nanoparticles from Arum dioscoridis plant leaf aqueous extract: anticancer and antimicrobial properties

Polat İpek; Mehmet Fırat Baran; Reşit Yıldız; Abdulkerim Hatipoğlu

doi:10.31015/jaefs.2023.2.18

EN

Biosynthesis of silver nanoparticles from Arum dioscoridis plant leaf aqueous extract: anticancer and antimicrobial properties

Abstract

This study was carried out to synthesize silver nanoparticles (AgNPs) from Arum dioscoridis (AD) leaf extract and to investigate the cytotoxic and antipathogenic effects of them. The plant material had a reducing and stabilizing effect on the synthesized nanomaterial. During the plant-mediated synthesis of nanomaterials, no substances that would cause environmental pollution were used. For the structural characterization of AD-AgNPs, Ultraviolet-visible (UV-vis) Spectroscopy, Field Emission Scanning Electron Microscopy (FE-SEM), Electron Dispersive X-ray (EDX) Spectroscopy, Fourier Transform Infrared (FT-IR) Spectroscopy, Transmission Electron Microscopy (TEM), X-ray Diffractometer (XRD), Atomic Force Microscopy (AFM) and Zetasizer analyses were performed. The produced AgNPs showed maximum surface plasmon resonance at 431.67 nm and had mostly spherical morphology. The zeta potential value of the nanomaterial was -9.76 mV and the average powder crystal size was 31.48 nm. The minimum inhibitory concentration (MIC) values (mg/L) of AD-AgNPs on Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, and Candida albicans were 0.25, 2.00, 0.125, 4.00, and 1.00, respectively. After 24 and 48 hours of application by MTT [3-(4,5-dimetiltiazol-2-il)-2,5-difeniltetrazolium bromid] assay, the half-maximal inhibitory concentrations (IC50: μg/mL) of AD-AgNPs on human colon adenocarcinoma cell (CACO-2), human breast cancer cell (MCF-7), glioblastoma multiforme cell (T98-G), and healthy human umbilical vein endothelial cell (HUVEC) lines were determined as 2.977, 2.801, 5.694, 4.392; 2.115, 2.300, 2.612, 4.091, respectively.

Keywords

AgNPs, Arum dioscoridis extract, Cytotoxicity, Green chemistry, Pathogen microorganism

Supporting Institution

Dicle University Scientific Research Projects Coordinatorship

Project Number

VETERINARY.21.002

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Details

Primary Language

English

Subjects

Food Engineering

Journal Section

Research Article

Authors

Polat İpek
0000-0003-1756-9757
Türkiye

Mehmet Fırat Baran
0000-0001-8133-6670
Türkiye

Reşit Yıldız
0000-0001-5467-6821
Türkiye

Abdulkerim Hatipoğlu ^*
0000-0002-1487-1953
Türkiye

Publication Date

June 29, 2023

Submission Date

May 11, 2023

Acceptance Date

June 4, 2023

Published in Issue

Year 2023 Volume: 7 Number: 2

DOI

https://doi.org/10.31015/jaefs.2023.2.18

IZ

https://izlik.org/JA23MZ34DP

APA

İpek, P., Baran, M. F., Yıldız, R., & Hatipoğlu, A. (2023). Biosynthesis of silver nanoparticles from Arum dioscoridis plant leaf aqueous extract: anticancer and antimicrobial properties. International Journal of Agriculture Environment and Food Sciences, 7(2), 399-407. https://doi.org/10.31015/jaefs.2023.2.18

AMA

1.İpek P, Baran MF, Yıldız R, Hatipoğlu A. Biosynthesis of silver nanoparticles from Arum dioscoridis plant leaf aqueous extract: anticancer and antimicrobial properties. int. j. agric. environ. food sci. 2023;7(2):399-407. doi:10.31015/jaefs.2023.2.18

Chicago

İpek, Polat, Mehmet Fırat Baran, Reşit Yıldız, and Abdulkerim Hatipoğlu. 2023. “Biosynthesis of Silver Nanoparticles from Arum Dioscoridis Plant Leaf Aqueous Extract: Anticancer and Antimicrobial Properties”. International Journal of Agriculture Environment and Food Sciences 7 (2): 399-407. https://doi.org/10.31015/jaefs.2023.2.18.

EndNote

İpek P, Baran MF, Yıldız R, Hatipoğlu A (June 1, 2023) Biosynthesis of silver nanoparticles from Arum dioscoridis plant leaf aqueous extract: anticancer and antimicrobial properties. International Journal of Agriculture Environment and Food Sciences 7 2 399–407.

IEEE

[1]P. İpek, M. F. Baran, R. Yıldız, and A. Hatipoğlu, “Biosynthesis of silver nanoparticles from Arum dioscoridis plant leaf aqueous extract: anticancer and antimicrobial properties”, int. j. agric. environ. food sci., vol. 7, no. 2, pp. 399–407, June 2023, doi: 10.31015/jaefs.2023.2.18.

ISNAD

İpek, Polat - Baran, Mehmet Fırat - Yıldız, Reşit - Hatipoğlu, Abdulkerim. “Biosynthesis of Silver Nanoparticles from Arum Dioscoridis Plant Leaf Aqueous Extract: Anticancer and Antimicrobial Properties”. International Journal of Agriculture Environment and Food Sciences 7/2 (June 1, 2023): 399-407. https://doi.org/10.31015/jaefs.2023.2.18.

JAMA

1.İpek P, Baran MF, Yıldız R, Hatipoğlu A. Biosynthesis of silver nanoparticles from Arum dioscoridis plant leaf aqueous extract: anticancer and antimicrobial properties. int. j. agric. environ. food sci. 2023;7:399–407.

MLA

İpek, Polat, et al. “Biosynthesis of Silver Nanoparticles from Arum Dioscoridis Plant Leaf Aqueous Extract: Anticancer and Antimicrobial Properties”. International Journal of Agriculture Environment and Food Sciences, vol. 7, no. 2, June 2023, pp. 399-07, doi:10.31015/jaefs.2023.2.18.

Vancouver

1.Polat İpek, Mehmet Fırat Baran, Reşit Yıldız, Abdulkerim Hatipoğlu. Biosynthesis of silver nanoparticles from Arum dioscoridis plant leaf aqueous extract: anticancer and antimicrobial properties. int. j. agric. environ. food sci. 2023 Jun. 1;7(2):399-407. doi:10.31015/jaefs.2023.2.18

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Biosynthesis of silver nanoparticles from Arum dioscoridis plant leaf aqueous extract: anticancer and antimicrobial properties

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Biosynthesis of silver nanoparticles from Arum dioscoridis plant leaf aqueous extract: anticancer and antimicrobial properties

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