Pseudohypoparathyroidism and Seizure: A Rare Case Report
Abstract
Pseudohypoparathyroidism
is characterized by hypocalcemia, hyperphosphatemia, increased serum
parathyroid hormone values and insensitivity to the biological activity of
parathyroid hormone. Pseudohypoparathyroidism is often associated with a
characteristic phenotype known as Albright‘s hereditary osteodystrophy.
Pseudohypoparathyroidism usually presents at an early age. We describe a 50-year-old man who
presented with seizure
due to hypocalcemia. He has typical features of Albright's
hereditary osteodystrophy, which include a round face, short neck and
stature. Diffuse
calsifications were seen on the bilateral cerebellum, putamen and
dentate nucleus in computerized tomography. The patient is treated successfully by calcium
carbonate and calcitriol supplementation
This case was reported in order to remind pseudohypoparathyroidism in patients
with hypocalcemic seizures.
Keywords
References
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- Liu J, Erlichman B, Weinstein LS. The stimulatory G protein alpha-subunit Gs alpha is imprinted in human thyroid glands: implications for thyroid function in pseudohypoparathyroidism types 1A and 1B. J Clin Endocrinol Metab 2003;88:4336–4341
- Mantovani G. Pseudohypoparathyroidism: diagnosis and treatment. The Journal of Clinical Endocrinology & Metabolism 2011;96:3020-3030.
Details
Primary Language
English
Subjects
-
Journal Section
Case Report
Authors
Ferhat Gökay
KAYSERİ EĞİTİM VE ARAŞTIRMA HASTANESİ
Türkiye
Yasin Şimşek
This is me
KAYSERİ EĞİTİM VE ARAŞTIRMA HASTANESİ
Türkiye
Oğuzhan Sitki Dizdar
This is me
KAYSERİ EĞİTİM VE ARAŞTIRMA HASTANESİ
Türkiye
Publication Date
August 17, 2018
Submission Date
January 10, 2017
Acceptance Date
August 17, 2018
Published in Issue
Year 2018 Volume: 3 Number: 2