Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul

Sema Alaçam; Ayfer Bakır; Aysel Karatas; Belkıs Yolburun; Özlem Uzunkaya; Ferda Aktaş; Mehmet Canberk

Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul

Abstract

Aim: Toxoplasma, rubella and cytomegalovirus (CMV) are among the most common intrauterine infection agents associated with congenital anomalies in the world. In this study, it was aimed to determine the seroprevalence of toxoplasma, rubella and CMV in pregnant women in Istanbul by ELISA screening tests, to evaluate them according to three different age groups and to compare them with the literature. Material and Methods: In 5485 serum samples of pregnant women, IgM and IgG antibodies against toxoplasma, rubella and CMV were investigated and total of 16496 tests were evaluated retrospectively. Samples were tested on the Architect i2000SR (Abbott Diagnostics, USA) using kits based on the chemiluminescence microparticle enzyme immunassay principle (Architect, USA). Results: Toxoplasma, rubella and CMV IgM positivity rates were 0.6%, 0.3% and 2.7%, respectively, and 23%, 89.1% and 98.7% for IgG, respectively. The toxoplasma IgG seropositivity rate was highest in the 36-49 age group (p =0.012). The toxoplasma IgM seropositivity rate was the lowest in the 26-35 age group (0.5%). The lowest rubella and CMV IgG seropositivity were found in 36-49 (87.8%) and 26-35 (98.4%) age groups. Conclusion: In pregnant women, serological screening tests seem to be important for monitoring and informing high risk groups, especially seronegative, due to the low seroprevalence of toxoplasma. However, routine screening of rubella and CMV in the pregnant population should be questioned due to the high immunity rates.

Keywords

References

Referans1 RK, Maity S, Saha S. A review on TORCH: groups of congenital infection during pregnancy. J Sci Innov Res. 2014;3(2):258–64.
Referans2 Akpınar O, Akpınar H. Investıgatıon of the rubella and cytomegalovırus seroprevalences by ELISA method ın pregnant women. Balikesir Saglik Bil Derg. 2017;6:11–5.
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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Sema Alaçam ^*
0000-0001-7957-2906
Türkiye

Ayfer Bakır
0000-0002-9006-5267
Türkiye

Aysel Karatas
0000-0001-8916-8499
Türkiye

Belkıs Yolburun This is me
0000-0003-1877-2757
Türkiye

Özlem Uzunkaya This is me
0000-0001-7238-1904
Türkiye

Ferda Aktaş This is me
0000-0002-4664-5213
Türkiye

Mehmet Canberk This is me
0000-0002-3715-3014
Türkiye

Publication Date

December 1, 2020

Submission Date

October 23, 2020

Acceptance Date

November 21, 2020

Published in Issue

Year 2020 Volume: 5 Number: 3

IZ

https://izlik.org/JA38WH56BZ

Cite

RIS / Bibtex

APA

Alaçam, S., Bakır, A., Karatas, A., Yolburun, B., Uzunkaya, Ö., Aktaş, F., & Canberk, M. (2020). Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul. Journal of Anatolian Medical Research, 5(3), 19-24. https://izlik.org/JA38WH56BZ

AMA

1.Alaçam S, Bakır A, Karatas A, et al. Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul. JAMER. 2020;5(3):19-24. https://izlik.org/JA38WH56BZ

Chicago

Alaçam, Sema, Ayfer Bakır, Aysel Karatas, et al. 2020. “Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul”. Journal of Anatolian Medical Research 5 (3): 19-24. https://izlik.org/JA38WH56BZ.

EndNote

Alaçam S, Bakır A, Karatas A, Yolburun B, Uzunkaya Ö, Aktaş F, Canberk M (December 1, 2020) Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul. Journal of Anatolian Medical Research 5 3 19–24.

IEEE

[1]S. Alaçam et al., “Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul”, JAMER, vol. 5, no. 3, pp. 19–24, Dec. 2020, [Online]. Available: https://izlik.org/JA38WH56BZ

ISNAD

Alaçam, Sema - Bakır, Ayfer - Karatas, Aysel - Yolburun, Belkıs - Uzunkaya, Özlem - Aktaş, Ferda - Canberk, Mehmet. “Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul”. Journal of Anatolian Medical Research 5/3 (December 1, 2020): 19-24. https://izlik.org/JA38WH56BZ.

JAMA

1.Alaçam S, Bakır A, Karatas A, Yolburun B, Uzunkaya Ö, Aktaş F, Canberk M. Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul. JAMER. 2020;5:19–24.

MLA

Alaçam, Sema, et al. “Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul”. Journal of Anatolian Medical Research, vol. 5, no. 3, Dec. 2020, pp. 19-24, https://izlik.org/JA38WH56BZ.

Vancouver

1.Sema Alaçam, Ayfer Bakır, Aysel Karatas, Belkıs Yolburun, Özlem Uzunkaya, Ferda Aktaş, Mehmet Canberk. Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul. JAMER [Internet]. 2020 Dec. 1;5(3):19-24. Available from: https://izlik.org/JA38WH56BZ