Araştırma Makalesi

Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul

Cilt: 5 Sayı: 3 1 Aralık 2020
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Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul

Öz

Aim: Toxoplasma, rubella and cytomegalovirus (CMV) are among the most common intrauterine infection agents associated with congenital anomalies in the world. In this study, it was aimed to determine the seroprevalence of toxoplasma, rubella and CMV in pregnant women in Istanbul by ELISA screening tests, to evaluate them according to three different age groups and to compare them with the literature. Material and Methods: In 5485 serum samples of pregnant women, IgM and IgG antibodies against toxoplasma, rubella and CMV were investigated and total of 16496 tests were evaluated retrospectively. Samples were tested on the Architect i2000SR (Abbott Diagnostics, USA) using kits based on the chemiluminescence microparticle enzyme immunassay principle (Architect, USA). Results: Toxoplasma, rubella and CMV IgM positivity rates were 0.6%, 0.3% and 2.7%, respectively, and 23%, 89.1% and 98.7% for IgG, respectively. The toxoplasma IgG seropositivity rate was highest in the 36-49 age group (p =0.012). The toxoplasma IgM seropositivity rate was the lowest in the 26-35 age group (0.5%). The lowest rubella and CMV IgG seropositivity were found in 36-49 (87.8%) and 26-35 (98.4%) age groups. Conclusion: In pregnant women, serological screening tests seem to be important for monitoring and informing high risk groups, especially seronegative, due to the low seroprevalence of toxoplasma. However, routine screening of rubella and CMV in the pregnant population should be questioned due to the high immunity rates.

Anahtar Kelimeler

Kaynakça

  1. Referans1 RK, Maity S, Saha S. A review on TORCH: groups of congenital infection during pregnancy. J Sci Innov Res. 2014;3(2):258–64.
  2. Referans2 Akpınar O, Akpınar H. Investıgatıon of the rubella and cytomegalovırus seroprevalences by ELISA method ın pregnant women. Balikesir Saglik Bil Derg. 2017;6:11–5.
  3. Referans3 Boyer SG, Boyer KM. Update on TORCH infections in the newborn infant. Newborn Infant Nurs Rev. 2004 Mar 1;4(1):70–80.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

1 Aralık 2020

Gönderilme Tarihi

23 Ekim 2020

Kabul Tarihi

21 Kasım 2020

Yayımlandığı Sayı

Yıl 2020 Cilt: 5 Sayı: 3

Kaynak Göster

APA
Alaçam, S., Bakır, A., Karatas, A., Yolburun, B., Uzunkaya, Ö., Aktaş, F., & Canberk, M. (2020). Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul. Journal of Anatolian Medical Research, 5(3), 19-24. https://izlik.org/JA38WH56BZ
AMA
1.Alaçam S, Bakır A, Karatas A, vd. Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul. JAMER. 2020;5(3):19-24. https://izlik.org/JA38WH56BZ
Chicago
Alaçam, Sema, Ayfer Bakır, Aysel Karatas, vd. 2020. “Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul”. Journal of Anatolian Medical Research 5 (3): 19-24. https://izlik.org/JA38WH56BZ.
EndNote
Alaçam S, Bakır A, Karatas A, Yolburun B, Uzunkaya Ö, Aktaş F, Canberk M (01 Aralık 2020) Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul. Journal of Anatolian Medical Research 5 3 19–24.
IEEE
[1]S. Alaçam vd., “Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul”, JAMER, c. 5, sy 3, ss. 19–24, Ara. 2020, [çevrimiçi]. Erişim adresi: https://izlik.org/JA38WH56BZ
ISNAD
Alaçam, Sema - Bakır, Ayfer - Karatas, Aysel - Yolburun, Belkıs - Uzunkaya, Özlem - Aktaş, Ferda - Canberk, Mehmet. “Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul”. Journal of Anatolian Medical Research 5/3 (01 Aralık 2020): 19-24. https://izlik.org/JA38WH56BZ.
JAMA
1.Alaçam S, Bakır A, Karatas A, Yolburun B, Uzunkaya Ö, Aktaş F, Canberk M. Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul. JAMER. 2020;5:19–24.
MLA
Alaçam, Sema, vd. “Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul”. Journal of Anatolian Medical Research, c. 5, sy 3, Aralık 2020, ss. 19-24, https://izlik.org/JA38WH56BZ.
Vancouver
1.Sema Alaçam, Ayfer Bakır, Aysel Karatas, Belkıs Yolburun, Özlem Uzunkaya, Ferda Aktaş, Mehmet Canberk. Investigation of Seroprevalence of Toxoplasma, Rubella and Cytomegalovirus in Pregnant Population in Istanbul. JAMER [Internet]. 01 Aralık 2020;5(3):19-24. Erişim adresi: https://izlik.org/JA38WH56BZ