Case Report

Infantile and Adult Scabies mimicking Langerhans Cell Histiocytosis Clinically and Histopathologically

Volume: 12 Number: 5 September 30, 2022
TR EN

Infantile and Adult Scabies mimicking Langerhans Cell Histiocytosis Clinically and Histopathologically

Abstract

Scabies is an infestation caused by the Sarcoptes scabiei burrowing into the epidermis. Histopathologically scabies infestation may reveal Langerhans cell hyperplasia which might cause misdiagnosis of Langerhans cell histiocytosis in some cases. We presented an infant and an adult who had a misdiagnosis of Langerhans cell histiocytosis (LCH) histopathologically and responded well to antiscabietic treatments. Therefore, awareness of this phenomenon might help clinicans to differentiate these two diseases with distinct prognosis and treatments.

Keywords

References

  1. Sunderkötter C, Feldmeier H, Fölster-Holst R, et al. S1 guidelines on the diagnosis and treatment of scabies – short version. JDDG: Journal der Deutschen Dermatologischen Gesellschaft 2016;14:1155-67.
  2. Sánchez-Borges M, González-Aveledo L, Capriles-Hulett A, et al. Scabies, crusted (Norwegian) scabies and the diagnosis of mite sensitisation. Allergol Immunopathol (Madr) 2018;46:276-80.
  3. Janik-Moszant A, Tomaszewska R, Szczepański T, et al. Infantile scabies or Langerhans cell histiocytosis? Med Pediatr Oncol 2003;40:111-2.
  4. Tidman MJ, Adamson B, Allan S, et al. Childhood scabies mistaken for Langerhans cell histiocytosis. Clin Exp Dermatol 2003;28:111-2.
  5. Burch JM, Krol A, Weston WL. Sarcoptes scabiei infestation misdiagnosed and treated as Langerhans cell histiocytosis. Pediatr Dermatol 2004;21:58-62.
  6. Bhattacharjee P, Glusac EJ. Langerhans cell hyperplasia in scabies: a mimic of Langerhans cell histiocytosis. J Cutan Pathol 2007;34:716-20.
  7. Yang YS, Byun YS, Kim JH, et al. Infantile Scabies Masquerading as Langerhans Cell Histiocytosis. Ann Dermatol 2015;27:349-51.
  8. Ruby KN, Loo EY, Mann JA, et al. Post-scabietic nodules: Mimicker of infantile indeterminate cell histiocytosis and potential diagnostic pitfall. J Cutan Pathol 2020;47:52-6.

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Case Report

Publication Date

September 30, 2022

Submission Date

November 16, 2021

Acceptance Date

August 18, 2022

Published in Issue

Year 2022 Volume: 12 Number: 5

APA
Manav, V., İlhan, D., Ergün, E., Erdil, D., Leblebici, C., & Koku Aksu, A. E. (2022). Infantile and Adult Scabies mimicking Langerhans Cell Histiocytosis Clinically and Histopathologically. Journal of Contemporary Medicine, 12(5), 817-819. https://doi.org/10.16899/jcm.1022846
AMA
1.Manav V, İlhan D, Ergün E, Erdil D, Leblebici C, Koku Aksu AE. Infantile and Adult Scabies mimicking Langerhans Cell Histiocytosis Clinically and Histopathologically. J Contemp Med. 2022;12(5):817-819. doi:10.16899/jcm.1022846
Chicago
Manav, Vildan, Dilara İlhan, Ecem Ergün, Duygu Erdil, Cem Leblebici, and Ayşe Esra Koku Aksu. 2022. “Infantile and Adult Scabies Mimicking Langerhans Cell Histiocytosis Clinically and Histopathologically”. Journal of Contemporary Medicine 12 (5): 817-19. https://doi.org/10.16899/jcm.1022846.
EndNote
Manav V, İlhan D, Ergün E, Erdil D, Leblebici C, Koku Aksu AE (September 1, 2022) Infantile and Adult Scabies mimicking Langerhans Cell Histiocytosis Clinically and Histopathologically. Journal of Contemporary Medicine 12 5 817–819.
IEEE
[1]V. Manav, D. İlhan, E. Ergün, D. Erdil, C. Leblebici, and A. E. Koku Aksu, “Infantile and Adult Scabies mimicking Langerhans Cell Histiocytosis Clinically and Histopathologically”, J Contemp Med, vol. 12, no. 5, pp. 817–819, Sept. 2022, doi: 10.16899/jcm.1022846.
ISNAD
Manav, Vildan - İlhan, Dilara - Ergün, Ecem - Erdil, Duygu - Leblebici, Cem - Koku Aksu, Ayşe Esra. “Infantile and Adult Scabies Mimicking Langerhans Cell Histiocytosis Clinically and Histopathologically”. Journal of Contemporary Medicine 12/5 (September 1, 2022): 817-819. https://doi.org/10.16899/jcm.1022846.
JAMA
1.Manav V, İlhan D, Ergün E, Erdil D, Leblebici C, Koku Aksu AE. Infantile and Adult Scabies mimicking Langerhans Cell Histiocytosis Clinically and Histopathologically. J Contemp Med. 2022;12:817–819.
MLA
Manav, Vildan, et al. “Infantile and Adult Scabies Mimicking Langerhans Cell Histiocytosis Clinically and Histopathologically”. Journal of Contemporary Medicine, vol. 12, no. 5, Sept. 2022, pp. 817-9, doi:10.16899/jcm.1022846.
Vancouver
1.Vildan Manav, Dilara İlhan, Ecem Ergün, Duygu Erdil, Cem Leblebici, Ayşe Esra Koku Aksu. Infantile and Adult Scabies mimicking Langerhans Cell Histiocytosis Clinically and Histopathologically. J Contemp Med. 2022 Sep. 1;12(5):817-9. doi:10.16899/jcm.1022846