Retrospective evaluation of laboratory, radiological and clinical findings of COVID-19 suspected cases with a public health perspective in Adiyaman Training and Research Hospital
Year 2021,
, 469 - 473, 31.07.2021
Ferit Kaya
,
Gülnur Tarhan
,
Sadık Akgün
,
Hakan Sezgin Sayiner
,
Ercan Çil
,
Uğur Lök
,
Safiye Kafadar
,
Furkan Bakirhan
Abstract
Aim: The purpose of this study is to evaluate SARS-CoV-2 cases based on clinical evidence from the perspective of public health.
Materials and Methods: The data of 354 people were analyzed which were among the patients admitted to the pandemic hospital in Adiyaman in the study.
Results: 70.6% of those admitted to the hospital with suspected COVID-19, 60% of those received inpatient treatment and 61.2% of those who were PCR-positive were male. The median age of those admitted to the hospital was 37 years. 90% were in a good general condition. The median length of hospitalization was 7 days. 14.8% PCR-positive patients required mechanical ventilation. Generally, D-dimer, CRP and WBC levels were poor, which were higher in those receiving intensive care (p<0.05).
Conclusion: As a result, the disease seems to be more common among men. CT abnormalities are common. D-Dimer, CRP and WBC levels are associated with severe disease.
References
- 1. İtil O, Altınışık Ergur G, Köktürk N, Havlucu Y, Akgün M, Aykaç N, eds. COVID-19 Pandemisi ve Sağlığın Sosyal Bileşenleri, Türk Toraks Derneği COVID-19 E-Kitapları Serisi, Haziran.; 2020
- 2. Seker M, Özer A, Tosun Z, Korkut C, Doğrul M. Covid-19 Pandemi Değerlendirme Raporu.; 2020. Accessed September 16, 2020.
- 3. Lauer SA, Grantz KH, Bi Q, et al. The incubation period of coronavirus disease 2019 (CoVID-19) from publicly reported confirmed cases: Estimation and application. Annals of Internal Medicine. 2020;172(9):577-582.
- 4. Pérez A, Santamaria EK, Operario D, et al. World Health Organization (2020). Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). Vol 5.; 2017. Accessed October 14, 2020.
- 5. Karaca B. Clinical Findings of the COVID-19 in the Adult Group. J Biotechnol and Strategic Health Res. 2020;1:85-90.
- 6. Pan A, Liu L, Wang C, et al. Association of Public Health Interventions with the Epidemiology of the COVID-19 Outbreak in Wuhan, China. JAMA. 2020;323(19):1915-1923.
- 7. Argenzian MG, Bruc SL, Slate CL, et al. Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: Retrospective case series. The BMJ. 2020;369.
- 8. Mardani R, Ahmadi Vasmehjani A, Zali F, et al. Laboratory Parameters in Detection of COVID-19 Patients with Positive RT-PCR; a Diagnostic Accuracy Study. Archives of academic emergency medicine. 2020;8(1):e43.
- 9. Thai PQ, Toan DTT, Dinh TS, et al. Factors associated with the duration of hospitalization among COVID-19 patients in Vietnam: A survival analysis. Epidemiology and Infection. 2020;148.
- 10. Hur K, Price CPE, Gray EL, et al. Factors Associated With Intubation and Prolonged Intubation in Hospitalized Patients With COVID-19. Otolaryngology - Head and Neck Surgery (United States). 2020;163(1):170-178. doi:10.1177/0194599820929640
- 11. Halaçli B, Kaya A, Topeli A. Critically ill COVID-19 patient. Turkish Journal of Medical Sciences. 2020;50(SI-1):585-591.
- 12. Wu Y, Hou B, Liu J, Chen Y, Zhong P. Risk Factors Associated With Long-Term Hospitalization in Patients With COVID-19: A Single-Centered, Retrospective Study. Frontiers in Medicine. 2020;7:315.
- 13. Karagiannidis C, Mostert C, Hentschker C, et al. Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study. The Lancet Respiratory Medicine. 2020;8(9):853-862.
- 14. To KKW, Tsang OTY, Leung WS, et al. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. The Lancet Infectious Diseases. 2020;20(5):565-574.
- 15. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020;395(10229):1054-1062.
16. Petrilli C, Jones S, Yang J, et al. Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City. BMJ. Published online April 11, 2020:2020.04.08.20057794.
- 17. Wang L. C-reactive protein levels in the early stage of COVID-19. Medecine et Maladies Infectieuses. 2020;50(4):332-334.
- 18. Zhang L, Yan X, Fan Q, et al. D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19. Journal of Thrombosis and Haemostasis. 2020;18(6):1324-1329.
- 19. Mooiweer E, Luijk B, Bonten MJM, Ekkelenkamp MB. C-Reactive protein levels but not CRP dynamics predict mortality in patients with pneumococcal pneumonia. Journal of Infection. 2011;62(4):314-316.
- 20. Satici C, Demirkol MA, Sargin Altunok E, et al. Performance of pneumonia severity index and CURB-65 in predicting 30-day mortality in patients with COVID-19. International Journal of Infectious Diseases. 2020;98:84-89.
Adıyaman Eğitim Araştırma Hastanesine başvuran COVID-19 şüpheli vakaların laboratuvar, radyolojik ve klinik bulgularının halk sağlığı bakışıyla retrospektif değerlendirilmesi
Year 2021,
, 469 - 473, 31.07.2021
Ferit Kaya
,
Gülnur Tarhan
,
Sadık Akgün
,
Hakan Sezgin Sayiner
,
Ercan Çil
,
Uğur Lök
,
Safiye Kafadar
,
Furkan Bakirhan
Abstract
Amaç: Bu çalışmanın amacı, SARS-CoV-2 vakalarını halk sağlığı perspektifinden klinik kanıtlara dayalı olarak değerlendirmektir.
Gereç ve Yöntem: Araştırmada Adıyaman pandemi hastanesine başvuran hastalardan 354 kişinin verileri incelendi.
Bulgular: Hastaneye COVID-19 şüphesi ile başvuranların %70,6'sı, yatarak tedavi görenlerin %60'ı ve PCR pozitif olanların% 61,2'si erkekti. Hastaneye başvuranların ortanca yaşı 37 idi. % 90'ı genel olarak iyi durumdaydı. Ortanca hastanede kalış süresi 7 gündü. PCR pozitif hastaların% 14.8'i mekanik ventilasyona ihtiyaç duydu. Genel olarak D-dimer, CRP ve WBC seviyeleri zayıftı ve yoğun bakım alanlarda daha yüksekti (p<0.05)
Sonuç: Sonuç olarak, hastalık erkekler arasında daha yaygın görünmektedir. BT anormallikleri yaygındır. D-Dimer, CRP ve WBC seviyeleri ciddi hastalıkla ilişkilidir.
Supporting Institution
yok
References
- 1. İtil O, Altınışık Ergur G, Köktürk N, Havlucu Y, Akgün M, Aykaç N, eds. COVID-19 Pandemisi ve Sağlığın Sosyal Bileşenleri, Türk Toraks Derneği COVID-19 E-Kitapları Serisi, Haziran.; 2020
- 2. Seker M, Özer A, Tosun Z, Korkut C, Doğrul M. Covid-19 Pandemi Değerlendirme Raporu.; 2020. Accessed September 16, 2020.
- 3. Lauer SA, Grantz KH, Bi Q, et al. The incubation period of coronavirus disease 2019 (CoVID-19) from publicly reported confirmed cases: Estimation and application. Annals of Internal Medicine. 2020;172(9):577-582.
- 4. Pérez A, Santamaria EK, Operario D, et al. World Health Organization (2020). Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). Vol 5.; 2017. Accessed October 14, 2020.
- 5. Karaca B. Clinical Findings of the COVID-19 in the Adult Group. J Biotechnol and Strategic Health Res. 2020;1:85-90.
- 6. Pan A, Liu L, Wang C, et al. Association of Public Health Interventions with the Epidemiology of the COVID-19 Outbreak in Wuhan, China. JAMA. 2020;323(19):1915-1923.
- 7. Argenzian MG, Bruc SL, Slate CL, et al. Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: Retrospective case series. The BMJ. 2020;369.
- 8. Mardani R, Ahmadi Vasmehjani A, Zali F, et al. Laboratory Parameters in Detection of COVID-19 Patients with Positive RT-PCR; a Diagnostic Accuracy Study. Archives of academic emergency medicine. 2020;8(1):e43.
- 9. Thai PQ, Toan DTT, Dinh TS, et al. Factors associated with the duration of hospitalization among COVID-19 patients in Vietnam: A survival analysis. Epidemiology and Infection. 2020;148.
- 10. Hur K, Price CPE, Gray EL, et al. Factors Associated With Intubation and Prolonged Intubation in Hospitalized Patients With COVID-19. Otolaryngology - Head and Neck Surgery (United States). 2020;163(1):170-178. doi:10.1177/0194599820929640
- 11. Halaçli B, Kaya A, Topeli A. Critically ill COVID-19 patient. Turkish Journal of Medical Sciences. 2020;50(SI-1):585-591.
- 12. Wu Y, Hou B, Liu J, Chen Y, Zhong P. Risk Factors Associated With Long-Term Hospitalization in Patients With COVID-19: A Single-Centered, Retrospective Study. Frontiers in Medicine. 2020;7:315.
- 13. Karagiannidis C, Mostert C, Hentschker C, et al. Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study. The Lancet Respiratory Medicine. 2020;8(9):853-862.
- 14. To KKW, Tsang OTY, Leung WS, et al. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. The Lancet Infectious Diseases. 2020;20(5):565-574.
- 15. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020;395(10229):1054-1062.
16. Petrilli C, Jones S, Yang J, et al. Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City. BMJ. Published online April 11, 2020:2020.04.08.20057794.
- 17. Wang L. C-reactive protein levels in the early stage of COVID-19. Medecine et Maladies Infectieuses. 2020;50(4):332-334.
- 18. Zhang L, Yan X, Fan Q, et al. D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19. Journal of Thrombosis and Haemostasis. 2020;18(6):1324-1329.
- 19. Mooiweer E, Luijk B, Bonten MJM, Ekkelenkamp MB. C-Reactive protein levels but not CRP dynamics predict mortality in patients with pneumococcal pneumonia. Journal of Infection. 2011;62(4):314-316.
- 20. Satici C, Demirkol MA, Sargin Altunok E, et al. Performance of pneumonia severity index and CURB-65 in predicting 30-day mortality in patients with COVID-19. International Journal of Infectious Diseases. 2020;98:84-89.