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Retrospective evaluation of laboratory, radiological and clinical findings of COVID-19 suspected cases with a public health perspective in Adiyaman Training and Research Hospital

Year 2021, , 469 - 473, 31.07.2021
https://doi.org/10.16899/jcm.881440

Abstract

Aim: The purpose of this study is to evaluate SARS-CoV-2 cases based on clinical evidence from the perspective of public health.
Materials and Methods: The data of 354 people were analyzed which were among the patients admitted to the pandemic hospital in Adiyaman in the study.
Results: 70.6% of those admitted to the hospital with suspected COVID-19, 60% of those received inpatient treatment and 61.2% of those who were PCR-positive were male. The median age of those admitted to the hospital was 37 years. 90% were in a good general condition. The median length of hospitalization was 7 days. 14.8% PCR-positive patients required mechanical ventilation. Generally, D-dimer, CRP and WBC levels were poor, which were higher in those receiving intensive care (p<0.05).
Conclusion: As a result, the disease seems to be more common among men. CT abnormalities are common. D-Dimer, CRP and WBC levels are associated with severe disease.

References

  • 1. İtil O, Altınışık Ergur G, Köktürk N, Havlucu Y, Akgün M, Aykaç N, eds. COVID-19 Pandemisi ve Sağlığın Sosyal Bileşenleri, Türk Toraks Derneği COVID-19 E-Kitapları Serisi, Haziran.; 2020
  • 2. Seker M, Özer A, Tosun Z, Korkut C, Doğrul M. Covid-19 Pandemi Değerlendirme Raporu.; 2020. Accessed September 16, 2020.
  • 3. Lauer SA, Grantz KH, Bi Q, et al. The incubation period of coronavirus disease 2019 (CoVID-19) from publicly reported confirmed cases: Estimation and application. Annals of Internal Medicine. 2020;172(9):577-582.
  • 4. Pérez A, Santamaria EK, Operario D, et al. World Health Organization (2020). Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). Vol 5.; 2017. Accessed October 14, 2020.
  • 5. Karaca B. Clinical Findings of the COVID-19 in the Adult Group. J Biotechnol and Strategic Health Res. 2020;1:85-90.
  • 6. Pan A, Liu L, Wang C, et al. Association of Public Health Interventions with the Epidemiology of the COVID-19 Outbreak in Wuhan, China. JAMA. 2020;323(19):1915-1923.
  • 7. Argenzian MG, Bruc SL, Slate CL, et al. Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: Retrospective case series. The BMJ. 2020;369.
  • 8. Mardani R, Ahmadi Vasmehjani A, Zali F, et al. Laboratory Parameters in Detection of COVID-19 Patients with Positive RT-PCR; a Diagnostic Accuracy Study. Archives of academic emergency medicine. 2020;8(1):e43.
  • 9. Thai PQ, Toan DTT, Dinh TS, et al. Factors associated with the duration of hospitalization among COVID-19 patients in Vietnam: A survival analysis. Epidemiology and Infection. 2020;148.
  • 10. Hur K, Price CPE, Gray EL, et al. Factors Associated With Intubation and Prolonged Intubation in Hospitalized Patients With COVID-19. Otolaryngology - Head and Neck Surgery (United States). 2020;163(1):170-178. doi:10.1177/0194599820929640
  • 11. Halaçli B, Kaya A, Topeli A. Critically ill COVID-19 patient. Turkish Journal of Medical Sciences. 2020;50(SI-1):585-591.
  • 12. Wu Y, Hou B, Liu J, Chen Y, Zhong P. Risk Factors Associated With Long-Term Hospitalization in Patients With COVID-19: A Single-Centered, Retrospective Study. Frontiers in Medicine. 2020;7:315.
  • 13. Karagiannidis C, Mostert C, Hentschker C, et al. Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study. The Lancet Respiratory Medicine. 2020;8(9):853-862.
  • 14. To KKW, Tsang OTY, Leung WS, et al. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. The Lancet Infectious Diseases. 2020;20(5):565-574.
  • 15. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020;395(10229):1054-1062. 16. Petrilli C, Jones S, Yang J, et al. Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City. BMJ. Published online April 11, 2020:2020.04.08.20057794.
  • 17. Wang L. C-reactive protein levels in the early stage of COVID-19. Medecine et Maladies Infectieuses. 2020;50(4):332-334.
  • 18. Zhang L, Yan X, Fan Q, et al. D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19. Journal of Thrombosis and Haemostasis. 2020;18(6):1324-1329.
  • 19. Mooiweer E, Luijk B, Bonten MJM, Ekkelenkamp MB. C-Reactive protein levels but not CRP dynamics predict mortality in patients with pneumococcal pneumonia. Journal of Infection. 2011;62(4):314-316.
  • 20. Satici C, Demirkol MA, Sargin Altunok E, et al. Performance of pneumonia severity index and CURB-65 in predicting 30-day mortality in patients with COVID-19. International Journal of Infectious Diseases. 2020;98:84-89.

Adıyaman Eğitim Araştırma Hastanesine başvuran COVID-19 şüpheli vakaların laboratuvar, radyolojik ve klinik bulgularının halk sağlığı bakışıyla retrospektif değerlendirilmesi

Year 2021, , 469 - 473, 31.07.2021
https://doi.org/10.16899/jcm.881440

Abstract

Amaç: Bu çalışmanın amacı, SARS-CoV-2 vakalarını halk sağlığı perspektifinden klinik kanıtlara dayalı olarak değerlendirmektir.
Gereç ve Yöntem: Araştırmada Adıyaman pandemi hastanesine başvuran hastalardan 354 kişinin verileri incelendi.
Bulgular: Hastaneye COVID-19 şüphesi ile başvuranların %70,6'sı, yatarak tedavi görenlerin %60'ı ve PCR pozitif olanların% 61,2'si erkekti. Hastaneye başvuranların ortanca yaşı 37 idi. % 90'ı genel olarak iyi durumdaydı. Ortanca hastanede kalış süresi 7 gündü. PCR pozitif hastaların% 14.8'i mekanik ventilasyona ihtiyaç duydu. Genel olarak D-dimer, CRP ve WBC seviyeleri zayıftı ve yoğun bakım alanlarda daha yüksekti (p<0.05)
Sonuç: Sonuç olarak, hastalık erkekler arasında daha yaygın görünmektedir. BT anormallikleri yaygındır. D-Dimer, CRP ve WBC seviyeleri ciddi hastalıkla ilişkilidir.

Supporting Institution

yok

References

  • 1. İtil O, Altınışık Ergur G, Köktürk N, Havlucu Y, Akgün M, Aykaç N, eds. COVID-19 Pandemisi ve Sağlığın Sosyal Bileşenleri, Türk Toraks Derneği COVID-19 E-Kitapları Serisi, Haziran.; 2020
  • 2. Seker M, Özer A, Tosun Z, Korkut C, Doğrul M. Covid-19 Pandemi Değerlendirme Raporu.; 2020. Accessed September 16, 2020.
  • 3. Lauer SA, Grantz KH, Bi Q, et al. The incubation period of coronavirus disease 2019 (CoVID-19) from publicly reported confirmed cases: Estimation and application. Annals of Internal Medicine. 2020;172(9):577-582.
  • 4. Pérez A, Santamaria EK, Operario D, et al. World Health Organization (2020). Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). Vol 5.; 2017. Accessed October 14, 2020.
  • 5. Karaca B. Clinical Findings of the COVID-19 in the Adult Group. J Biotechnol and Strategic Health Res. 2020;1:85-90.
  • 6. Pan A, Liu L, Wang C, et al. Association of Public Health Interventions with the Epidemiology of the COVID-19 Outbreak in Wuhan, China. JAMA. 2020;323(19):1915-1923.
  • 7. Argenzian MG, Bruc SL, Slate CL, et al. Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: Retrospective case series. The BMJ. 2020;369.
  • 8. Mardani R, Ahmadi Vasmehjani A, Zali F, et al. Laboratory Parameters in Detection of COVID-19 Patients with Positive RT-PCR; a Diagnostic Accuracy Study. Archives of academic emergency medicine. 2020;8(1):e43.
  • 9. Thai PQ, Toan DTT, Dinh TS, et al. Factors associated with the duration of hospitalization among COVID-19 patients in Vietnam: A survival analysis. Epidemiology and Infection. 2020;148.
  • 10. Hur K, Price CPE, Gray EL, et al. Factors Associated With Intubation and Prolonged Intubation in Hospitalized Patients With COVID-19. Otolaryngology - Head and Neck Surgery (United States). 2020;163(1):170-178. doi:10.1177/0194599820929640
  • 11. Halaçli B, Kaya A, Topeli A. Critically ill COVID-19 patient. Turkish Journal of Medical Sciences. 2020;50(SI-1):585-591.
  • 12. Wu Y, Hou B, Liu J, Chen Y, Zhong P. Risk Factors Associated With Long-Term Hospitalization in Patients With COVID-19: A Single-Centered, Retrospective Study. Frontiers in Medicine. 2020;7:315.
  • 13. Karagiannidis C, Mostert C, Hentschker C, et al. Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study. The Lancet Respiratory Medicine. 2020;8(9):853-862.
  • 14. To KKW, Tsang OTY, Leung WS, et al. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. The Lancet Infectious Diseases. 2020;20(5):565-574.
  • 15. Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020;395(10229):1054-1062. 16. Petrilli C, Jones S, Yang J, et al. Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City. BMJ. Published online April 11, 2020:2020.04.08.20057794.
  • 17. Wang L. C-reactive protein levels in the early stage of COVID-19. Medecine et Maladies Infectieuses. 2020;50(4):332-334.
  • 18. Zhang L, Yan X, Fan Q, et al. D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19. Journal of Thrombosis and Haemostasis. 2020;18(6):1324-1329.
  • 19. Mooiweer E, Luijk B, Bonten MJM, Ekkelenkamp MB. C-Reactive protein levels but not CRP dynamics predict mortality in patients with pneumococcal pneumonia. Journal of Infection. 2011;62(4):314-316.
  • 20. Satici C, Demirkol MA, Sargin Altunok E, et al. Performance of pneumonia severity index and CURB-65 in predicting 30-day mortality in patients with COVID-19. International Journal of Infectious Diseases. 2020;98:84-89.
There are 19 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Research
Authors

Ferit Kaya 0000-0002-0261-6293

Gülnur Tarhan 0000-0002-1019-0798

Sadık Akgün 0000-0002-1413-0450

Hakan Sezgin Sayiner 0000-0002-4693-3784

Ercan Çil 0000-0002-8981-4232

Uğur Lök 0000-0002-6091-9401

Safiye Kafadar 0000-0003-4070-9615

Furkan Bakirhan 0000-0001-8588-6100

Publication Date July 31, 2021
Acceptance Date March 24, 2021
Published in Issue Year 2021

Cite

AMA Kaya F, Tarhan G, Akgün S, Sayiner HS, Çil E, Lök U, Kafadar S, Bakirhan F. Retrospective evaluation of laboratory, radiological and clinical findings of COVID-19 suspected cases with a public health perspective in Adiyaman Training and Research Hospital. J Contemp Med. July 2021;11(4):469-473. doi:10.16899/jcm.881440