IMMUNOTHERAPY AND POTENTIAL USE OF PROPOLIS IN CANCER IMMUNOTHERAPY

Abstract

In recent years cancer incidence has increased. Innovative studies have been carried out on the treatment methods of cancer, a major threat to public health. Immunotherapy is the treatment of the disease with therapeutic agents that increase or decrease immune responses. Immunotherapy is known to be effective in the treatment of cancer. A bee product, propolis that has been investigated for its availability in this respect draws attention because of its antitumor effects. In addition, immunomodulatory effects of propolis, which is known to have antibacterial, antimicrobial, antifungal, antiviral and cytotoxic effects, have been investigated in recent years. According to researchers, propolis is a promising compound in cancer immunotherapy. In this review, it is aimed to give information about immunotherapy and the use of propolis in cancer immunotherapy.

Keywords

• Immunotherapy,Propolis,Cancer,Immunomodulator

İMMÜNOTERAPİ VE PROPOLİSİN KANSER İMMÜNOTERAPİSİNDE KULLANIM POTANSİYELİ

Öz

Son yıllarda kanser hastalığı oldukça yaygın olarak görülmektedir. Halk sağlığı için büyük tehlike oluşturan kanser hastalığının tedavi yöntemleri üzerinde yenilikçi araştırmalar yapılmaktadır. İmmünoterapi immün yanıtları artıran veya azaltan terapötik ajanlar ile ortaya çıkan hastalığın tedavisidir. İmmünoterapinin kanser tedavisinde etkili olduğu bilinmektedir. Bu amaç doğrultusunda kullanılabilirliği araştırılan, bir arı ürünü olan propolis antitümör etkiler göstermesi ile dikkat çekmektedir. Bunun yanı sıra antibakteriyel, antimikrobiyal, antifungal, antiviral ve sitotoksik etkileri olduğu bilinmekte olan propolisin son yıllarda immünomodülatör etkileri incelenmektedir. Araştırmacılara göre propolis kanser immünoterapisinde umut vadeden bir bileşendir. Bu derlemede immünoterapi ve propolisin kanser immünoterapisinde kullanımı hakkında bilgi verilmesi amaçlanmaktadır.

Anahtar Kelimeler

• İmmünoterapi,Propolis,Kanser,İmmünomodulatör

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