Review
BibTex RIS Cite

Peynir Altı Suyu Protein Takviyesi ve Sağlık Üzerindeki Potansiyel Etkileri

Year 2022, Volume: 4 Issue: 3, 318 - 329, 25.12.2022

Abstract

Whey proteini (peynir altı suyu) besleyici değeri yüksek fonksiyonel bir besin olarak kabul edilen sütün bileşenlerinden biri olarak tanımlanmaktadır. Peynir yapımında bir yan ürün olarak elde edilen whey proteini tüm esansiyel amino asitleri içermektedir. Yüksek biyolojik değerinin yanı sıra antioksidan etki gösteren sülfür içeren amino asitler ve dallı zincirli amino asit (lösin, izolösin ve valin) içeriği açısından zengindir. ß-laktoglobulin, α-laktoalbumin, sığır serum albumini, immunoglobulinler, laktoferrin, laktoperoksidaz bileşenlerini ve düşük miktarda süt yağı içermesi nedeniyle sağlığı koruyucu potansiyel olumlu etkileri olan bir besindir. Whey proteini içerdiği biyolojik bileşenler; antiinflamatuar, antidiyabetik, antioksidan, antihipertansif, antitümör, antiviral, hipolipidemik ve antibakteriyel etki gibi önemli etkileri sağlamaktadır. Bu bağlamda obezite, diyabet, kanser, hepatit, kardiyovasküler hastalıklar ve insan immün yetmezlik (HIV) virüsünün tedavisinde olumlu yönde sonuçlara neden olabileceği düşünülmektedir.
Whey proteini, emülsifikasyon, jel oluşturma, köpürme, yağ bağlama kapasitesi, kıvam artırma gibi gelişmiş duyusal özellikleri ile çeşitli bileşenlerin yerine geçerek gıda endüstrisinde kullanımı yaygındır. Yüksek besin değeri, spesifik fonksiyonel özellikleri ve elde edilmesi esnasındaki sürdürülebilirliğe katkısı düşünüldüğünde besin ve sağlık endüstrisinde çeşitli uygulamalara sahip olabilen süt işlemenin sürdürülebilir çok değerli fonksiyonel ürünlerinden biridir. Bu derleme çalışmasının amacı PubMed, Science Direct ve Google Scholar veri tabanlarındaki verilerin incelenmesi doğrultusunda whey proteini takviyesinin sağlık üzerindeki potansiyel etkilerini ve gıda endüstrisindeki uygulamalarını değerlendirmektedir

References

  • Referans1 Abdel-Aziem S.H., Hassan A.M., Abdel-Wahhab M.A. (2011). Dietary supplementation with whey protein and ginseng extract counteracts oxidative stress and DNA damage in rats fed an aflatoxin-contaminated diet. Mutat Res, 723(1):65-71.
  • Referans2 Addai F.P., Lin F., Wang T., Kosiba A.A., Sheng P., Yu F., Gu J., Zhou Y., Shi H. (2020). Technical integrative approaches to cheese whey valorization towards sustainable environment. Food Funct, 21;11(10):8407-8423.
  • Referans3 Akkurt G. (2019). The effect of isolated hydrolyzed whey protein on thyroid hormones, liver and kidney function tests in individuals with regular weight exercise. Ankara Med J, 19;(1):178-86.
  • Referans4 Alpkent Z., Göncü A. (2016). Peynir suyu ve peynir suyu proteinlerinin gıda, kozmetik ve tıp alanlarında kullanımı. Gıda Mühendisliği Dergisi, 5 s.
  • Referans5 Altıner A. (2017). Peynir altı suyunun insan ve hayvanlarda metabolizma üzerindeki etkileri. Bahri Dağdaş Hayvancılık Araştırma Dergisi,6 (1): 29-42.
  • Referans6 Anderson G.H., Moore S.E. (2004). Dietary proteins in the regulation of food intake and body weight in humans. J Nutr, 134(4):974S-9S.
  • Referans7 Athira S., Mann B., Saini P., Sharma R., Kumar R., Singh A. K. (2014). Production and characterisation of whey protein hydrolysate having antioxidant activity from cheese whey. Journal of the Science of Food and Agriculture, 95(14), 2908–2915.
  • Referans8 Attaallah W. (2012). Whey protein versus whey protein hydrolyzate for the protection of azoxymethane and dextran sodium sulfate induced colonic tumors in rats. Pathol Oncol Res, 18(4):817-22.
  • Referans9 Badr G. (2012). Supplementation with undenatured whey protein during diabetes mellitus improves the healing and closure of diabetic wounds through the rescue of functional long-lived wound macrophages. Cell Physiol Biochem, 29(3-4):571-82.
  • Referans10 Baer D.J., Stote K.S., Paul D.R., Harris G.K., Rumpler W.V., Clevidence B.A. (2011). Whey protein but not soy protein supplementation alters body weight and composition in free-living overweight and obese adults. J Nutr, 141(8):1489-94.
  • Referans11 Balbis E. (2009). Whey proteins influence hepatic glutathione after CCl4 intoxication. Toxicol Ind Health, 25(4-5):325-8.
  • Referans12 Bosze Z. (2008). Bioactive components of milk. Advances in Experimental Medicine and Biology; 2008. Springer.
  • Referans13 Bösze Z., Baranyi M., Bruce C., Whitelaw A. (2008). Producing Recombinant Human Milk Proteins in the Milk of Livestock Species. In: Bösze Z. (eds), Bioactive Components of Milk. Advances in Experimental Medicine and Biology, vol 606. Springer, New York, NY.
  • Referans14 Bulut Solak N., Akın N. (2009). Nutritional value and health benefits of whey proteins, International Scientific Conference on Nutraceuticals and Functional Foods, Zilina, Slovakia, June 9th-11th, p.18.
  • Referans15 Cribb P.J., Williams A.D., Hayes A. (2007). A creatine-protein-carbohydrate supplement enhances responses to resistance training. Med Sci Sports Exerc ,39(11):1960-8.
  • Referans16 Cruz-Jentoft A.J., Baeyens J.P., Bauer J.M. (2010). Sarcopenia: European consensus on definition and diagnosis Report of the European Working Group on Sarcopenia in Older People. Age Ageing ,39(4):412-23.
  • Referans17 Dillon E.L., Basra G., Horstman A.M. (2012). Cancer cachexia and anabolic interventions: a case report. J. Cachex Sarcopenia Muscle ,3,253263.
  • Referans18 El-Shinnawy N.A., Abd Elhalem S.S., Haggag N.Z., Badr G. (2012). Ameliorative role of camel whey protein and rosuvastatin on induced dyslipidemia in mice. Food Funct, 21:1038-47.
  • Referans19 Gupta C., Prakash D., Garg A.P., Gupta S. (2012). Whey proteins: a novel source of bioceuticals. Middle East J. Sci. Res ,12, 365375.
  • Referans20 Gutman J.B.L., Kongshavn P.A.L. (2019). Cysteine/cystine-rich undenatured whey protein supplement in patients' pressure ulcers outcomes: an open label study. J Wound Care, 1;28(Sup7):S16-S23.
  • Referans21 Gülmez M. (2019). Peynir altı suyu. Süt Dünyası Dergisi, 72: 44-47.
  • Referans22 Hakkak R., Korourian S., Ronis, M.J., Johnston J.M., Badger T.M. (2001). Dietary whey protein protect. Cancer Epidemiol. Biomark. Prev ,10,555558.
  • Referans23 Harper W.J. (2000). Biological Properties of Whey Components. A Review. Chicago, IL: The American Dairy Products Institute.
  • Referans24 Horton B. (1998). The whey processing industry: Into the 21st century. Whey, Proceedings of the Second International Whey Conference. Chicogo. USA, 12.
  • Referans25 Hoseini S.M., Khosravi-Darani K., Mozafari M.R. (2013). Nutritional and medical applications of spirulina microalgae. Mini Rev Med Chem, 13(8):1231-7.
  • Referans26 Huffman L.M. (1998). The impoıtance of whey protein fractions for WPC and WPI functionality. Whey, Proceedings of the Second International Whey Conference. Chicogo, USA, 197.
  • Referans27 Hulmi J.J., Lockwood C.M., Stout J.R. (2010). Effect of protein/essential amino acids and resistance training on skeletal muscle hypertrophy: A case for whey protein. Nutr Metab, 17;7:51.
  • Referans28 Ikeda M., Sugiyama K., Tanaka T., Tanaka K., Sekihara H., Shimotohno K. (1998). Lactoferrin markedly inhibits hepatitis C virus infection in cultured human hepatocytes. Biochem. Biophys. Res. Commun, 245,549553.
  • Referans29 Jelen P. (2009). Whey-based functional beverages. In: Paquin, P. (ed.) Functional and speciality beverage technology. CRC Press, p. 259-296.
  • Referans30 Jelicic I., Botanic R., Tratnik R. (2008). Whey based beverages-new generation of dairy products. Mljekarstvo, 58: 257-274
  • Referans31 Jooyandeh H. (2009). Effect of fermented whey protein concentrate on texture of Iranian white cheese. Journal of Texture Studies, 40:497-510.
  • Referans32 Kassem J.M. (2015). Future challenges of whey proteins. Int. J. Dairy Sci, 10 (4), 139-159.
  • Referans33 Khalifa I., Peng J., Jia Y., Li J., Zhu W., Yu-Juan X. (2019). Anti-glycation and anti-hardening effects of microencapsulated mulberry polyphenols in high-protein- sugar ball models through binding with some glycation sites of whey proteins.International Journal of Biological Macromolecules, 123, 10–19.
  • Referans34 Kim D.H., Chun S.H., Oh N., Lee J.Y., Lee K.W. (2019). Anti-inflammatory activities of Maillard reaction products from whey protein isolate fermented by Lactobacillus gasseri 4M13 in lipopolysaccharide-stimulated RAW264.7 cells. Journal of Dairy Science, 102, (9), 7707-7716.
  • Referans35 Kimball S.R., Jefferson L.S.(2006). Signaling pathways and molecular mechanisms through which branched-chain amino acids mediate translational control of protein synthesis. J Nutr, 136(1 Suppl):227S-31S.
  • Referans36 Layman D.K., Lönnerdal B., Fernstrom J.D. (2018). Applications for α-lactalbumin in human nutrition. Nutr Rev, 1;76(6):444-460.
  • Referans37 Liberman K., Njemini R., Luiking Y., Forti L.N., Verlaan S., Bauer J.M. (2019). Thirteen weeks of supplementation of vitamin D and leucine-enriched whey protein nutritional supplement attenuates chronic low-grade inflammation in sarcopenic older adults: The provide study. Aging Clinical and Experimental Research, 31(6),845–854.
  • Referans38 Luhovyy B.L., Akhavan T., Anderson G.H.(2007). Whey proteins in the regulation of food intake and satiety. Journal of the American College of Nutrition, 26(6):704S-712S.
  • Referans39 Madadlou A., Abbaspourrad A. (2018). Bioactive whey peptide particles: An emerging class of nutraceutical carriers. Critical Reviews in Food Science and Nutrition, 58:(9), 1468–1477.
  • Referans40 Mangano K.M., Bao Y., Zhao C. (2019). Nutritional properties of whey proteins. Whey Protein Production, Chemistry, Functionality, and Applications, 103–140.
  • Referans41 Mann B., Kumari A., Kumar R., Sharma R., Prajapati K., Mahboob S. (2015). Antioxidant activity of whey protein hydrolysates in milk beverage system. Journal of Food Science and Technology, 52(6), 3235–3241.
  • Referans42 Marshall K. (2004). Therapeutic applications of whey protein. Altern. Med. Rev, 9,136-156.
  • Referans43 McClements J. (1995). Advances in the application of ultrasound in food analysis and processing. Trends Food Sci. Technol, 6, 293299.
  • Referans44 McIntosh G.H., Royle P.J., Le Leu R.K., Regester G.O., Johnson M.A., Grinsted R.L. (1998). Whey proteins as functional food ingredients. Int. Dairy J, 8, 425434.
  • Referans45 Micke P, Beeh KM, Buhl R (2002). Effects of longterm supplementation with whey proteins on plasma glutathione levels of HIV-infected patients. Eur J Nutr, 41(1):12-8.
  • Referans46 Miller P.E., Alexander D.D., Perez V. (2014). Effects of whey protein and resistance exercise on body composition: a meta-analysis of randomized controlled trials. J Am Coll Nutr, 33(2):163-75.
  • Referans47 Moreno Y.F., Sgarbieri V.C., Da Silva M.N., Toro A.A., Vilela M.M. (2006). Features of whey protein concentrate supplementation in children with rapidly progressive HIV infection, J. Trop. Pediatr. 52 (1):34-38.
  • Referans48 Morley J.E. (2007). Weight loss in older persons: new therapeutic approaches. Curr Pharm Des,13(35):3637-47.
  • Referans49 Mortensen L.S. (2012). Effects of different fractions of whey protein on postprandial lipid and hormone responses in type 2 diabetes. Eur J Clin Nutr, 66(7):799-805.
  • Referans50 Muro Urista C., Álvarez Fernández R., Riera Rodriguez F., Arana Cuenca A., Téllez Jurado A. (2011). Review: Production and functionality of active peptides from milk. Food Science and Technology International, 17(4), 293–317.
  • Referans51 Nabuco H.C.G., Tomeleri C.M., Fernandes R.R. (2019). Effects of pre- or post-exercise whey protein supplementation on oxidative stress and antioxidant enzymes in older women. Scand J Med Sci Sports, 29: 1101– 1108.
  • Referans52 Paddon-Jones D, Rasmussen B.B. (2009). Dietary protein recommendations and ththerapy. Curr Opin Clin Nutr Metab Care, 12(1):86-90.
  • Referans53 Pal S., Ellis V., Dhaliwal S. (2010). Effects of whey protein isolate on body composition, lipids, insulin and glucose in overweight and obese individuals. Br J Nutr, 104(5):716-23.
  • Referans54 Pal S., Ellis V. (2010). The chronic effects of whey proteins on blood pressure, vascular function, and inflammatory markers in overweight individuals. Obesity, 18, 13541359.
  • Referans55 Pal, S., Radavelli-Bagatini S. (2013). The effects of whey protein on cardiometabolic risk factors. Obesity Rev, 14: 324-343.
  • Referans56 Patel S. (2015). Emerging trends in nutraceutical applications of whey protein and its derivatives. J. Food Sci.Technol, 52 (11), 68476858.
  • Referans57 Perez-Cano F.J., Marın-Galle´n S., Castell M., Rodriguez-Palmero M., Rivero M., Franch A. (2007). Bovine whey protein concentrate supplementation modulates maturation of immune system in suckling rats. Br. J. Nutr, 98, S80S84.
  • Referans58 Philipina A. Marcelo H.R. (2008). Physicochemical properties of liquid virgin whey protein isolate. International Dairy Journal, 18:236-246.
  • Referans59 Pins J.J., Keenan J.M. (2002). Antihypertensive effects of a hydrolyzed whey protein isolate supplement (BioZate®1), Presented at the 11th International Congress on Cardiovascular Pharmacotherapy, Montreal, Quebec, Canada.
  • Referans60 Salehi A., Gunnerud U., Muhammed S.J. (2012). The insulinogenic effect of whey protein is partially mediated by a direct effect of amino acids and GIP on β-cells. NutrMetab , 9, 48.
  • Referans61 Shankar J.R., Bansal G.K., (2013). A study on health benefits of whey proteins. Int. J. Adv. Biotechnol. Res.,4 :15-19.
  • Referans62 Smithers G.W. (2008). Whey and whey proteins-From ‘gutter-to-gold’. International Dairy Journal., 18:695-704.
  • Referans63 Solak B.B., Akin N. (2012). Health benefits of whey protein: a review. J. Food Sci. Eng, 2, 129137.
  • Referans64 Sousa G.T.D., Lira F.S., Rosa J.C., Oliveira E.P., Oyama, L.M., Santos R.V. (2012). Dietary whey protein lessens several risk factors for metabolic diseases: a review. Lipids Health Dis, 11, 6775.
  • Referans65 Tang J.E., Moore D.R., Kuj S., Kellogg M.D., Maresh C.M., Kraemer W.J. (2013). Whey protein supplementation during resistance training augments lean body mass. J Am Coll Nutr, 32(2):122-35.
  • Referans66 Tomé D. (2009). Protein, amino acids, vagus nerve signaling, and the brain. The American Journal of Clinical Nutrition, 90(3): 838S-843S.
  • Referans67 Tripathi V., Jha Y.K. (2004). Development of Whey Beverage with Antagonistic Characteristics and Probiotics. International Journal of Food Properties, 7:2, 261-272.
  • Referans68 Tsai W.Y., Chang W.H., Chen C.H. (2000). Enchancing effect of patented whey protein isolate on cytotoxicity of an anticancer drug. Nutr. Cancer, 38:200-208.
  • Referans69 Tuomilehto J., Lindström J., Eriksson J.G. (2001). Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med, 344(18):1343-50.
  • Referans70 Van Loon L.J., Saris W.H., Verhagen H., Wagenmakers A.J. (2000). Plasma insulin responses after ingestion of different amino acid or protein mixtures with carbohydrate. Am. J. Clin. Nutr,721: 96-105.
  • Referans71 Wirunsawanya K., Upala S., Jaruvongvanich V., Sanguankeo A. (2018). Whey protein supplementation improves body composition and cardiovascular risk factors in overweight and obese patients: A systematic review and meta-analysis. J Am Coll Nutr, 37:60-70.
  • Referans72 Yamaguchi M., Yoshida K., Uchida M.(2009). Novel functions of bovine milk-derived alphalactalbumin: Anti-nociceptive and antiinflammatory activity caused by inhibiting cyclooxygenase-2 and phospholipase A2. Biol Pharm Bull,32(3):366-71.
  • Referans73 Zemel M.B. (2004). Role of calcium and dairy products in energy partitioning and weight management. Am J Clin Nutr,79(5):907S-12S.
Year 2022, Volume: 4 Issue: 3, 318 - 329, 25.12.2022

Abstract

References

  • Referans1 Abdel-Aziem S.H., Hassan A.M., Abdel-Wahhab M.A. (2011). Dietary supplementation with whey protein and ginseng extract counteracts oxidative stress and DNA damage in rats fed an aflatoxin-contaminated diet. Mutat Res, 723(1):65-71.
  • Referans2 Addai F.P., Lin F., Wang T., Kosiba A.A., Sheng P., Yu F., Gu J., Zhou Y., Shi H. (2020). Technical integrative approaches to cheese whey valorization towards sustainable environment. Food Funct, 21;11(10):8407-8423.
  • Referans3 Akkurt G. (2019). The effect of isolated hydrolyzed whey protein on thyroid hormones, liver and kidney function tests in individuals with regular weight exercise. Ankara Med J, 19;(1):178-86.
  • Referans4 Alpkent Z., Göncü A. (2016). Peynir suyu ve peynir suyu proteinlerinin gıda, kozmetik ve tıp alanlarında kullanımı. Gıda Mühendisliği Dergisi, 5 s.
  • Referans5 Altıner A. (2017). Peynir altı suyunun insan ve hayvanlarda metabolizma üzerindeki etkileri. Bahri Dağdaş Hayvancılık Araştırma Dergisi,6 (1): 29-42.
  • Referans6 Anderson G.H., Moore S.E. (2004). Dietary proteins in the regulation of food intake and body weight in humans. J Nutr, 134(4):974S-9S.
  • Referans7 Athira S., Mann B., Saini P., Sharma R., Kumar R., Singh A. K. (2014). Production and characterisation of whey protein hydrolysate having antioxidant activity from cheese whey. Journal of the Science of Food and Agriculture, 95(14), 2908–2915.
  • Referans8 Attaallah W. (2012). Whey protein versus whey protein hydrolyzate for the protection of azoxymethane and dextran sodium sulfate induced colonic tumors in rats. Pathol Oncol Res, 18(4):817-22.
  • Referans9 Badr G. (2012). Supplementation with undenatured whey protein during diabetes mellitus improves the healing and closure of diabetic wounds through the rescue of functional long-lived wound macrophages. Cell Physiol Biochem, 29(3-4):571-82.
  • Referans10 Baer D.J., Stote K.S., Paul D.R., Harris G.K., Rumpler W.V., Clevidence B.A. (2011). Whey protein but not soy protein supplementation alters body weight and composition in free-living overweight and obese adults. J Nutr, 141(8):1489-94.
  • Referans11 Balbis E. (2009). Whey proteins influence hepatic glutathione after CCl4 intoxication. Toxicol Ind Health, 25(4-5):325-8.
  • Referans12 Bosze Z. (2008). Bioactive components of milk. Advances in Experimental Medicine and Biology; 2008. Springer.
  • Referans13 Bösze Z., Baranyi M., Bruce C., Whitelaw A. (2008). Producing Recombinant Human Milk Proteins in the Milk of Livestock Species. In: Bösze Z. (eds), Bioactive Components of Milk. Advances in Experimental Medicine and Biology, vol 606. Springer, New York, NY.
  • Referans14 Bulut Solak N., Akın N. (2009). Nutritional value and health benefits of whey proteins, International Scientific Conference on Nutraceuticals and Functional Foods, Zilina, Slovakia, June 9th-11th, p.18.
  • Referans15 Cribb P.J., Williams A.D., Hayes A. (2007). A creatine-protein-carbohydrate supplement enhances responses to resistance training. Med Sci Sports Exerc ,39(11):1960-8.
  • Referans16 Cruz-Jentoft A.J., Baeyens J.P., Bauer J.M. (2010). Sarcopenia: European consensus on definition and diagnosis Report of the European Working Group on Sarcopenia in Older People. Age Ageing ,39(4):412-23.
  • Referans17 Dillon E.L., Basra G., Horstman A.M. (2012). Cancer cachexia and anabolic interventions: a case report. J. Cachex Sarcopenia Muscle ,3,253263.
  • Referans18 El-Shinnawy N.A., Abd Elhalem S.S., Haggag N.Z., Badr G. (2012). Ameliorative role of camel whey protein and rosuvastatin on induced dyslipidemia in mice. Food Funct, 21:1038-47.
  • Referans19 Gupta C., Prakash D., Garg A.P., Gupta S. (2012). Whey proteins: a novel source of bioceuticals. Middle East J. Sci. Res ,12, 365375.
  • Referans20 Gutman J.B.L., Kongshavn P.A.L. (2019). Cysteine/cystine-rich undenatured whey protein supplement in patients' pressure ulcers outcomes: an open label study. J Wound Care, 1;28(Sup7):S16-S23.
  • Referans21 Gülmez M. (2019). Peynir altı suyu. Süt Dünyası Dergisi, 72: 44-47.
  • Referans22 Hakkak R., Korourian S., Ronis, M.J., Johnston J.M., Badger T.M. (2001). Dietary whey protein protect. Cancer Epidemiol. Biomark. Prev ,10,555558.
  • Referans23 Harper W.J. (2000). Biological Properties of Whey Components. A Review. Chicago, IL: The American Dairy Products Institute.
  • Referans24 Horton B. (1998). The whey processing industry: Into the 21st century. Whey, Proceedings of the Second International Whey Conference. Chicogo. USA, 12.
  • Referans25 Hoseini S.M., Khosravi-Darani K., Mozafari M.R. (2013). Nutritional and medical applications of spirulina microalgae. Mini Rev Med Chem, 13(8):1231-7.
  • Referans26 Huffman L.M. (1998). The impoıtance of whey protein fractions for WPC and WPI functionality. Whey, Proceedings of the Second International Whey Conference. Chicogo, USA, 197.
  • Referans27 Hulmi J.J., Lockwood C.M., Stout J.R. (2010). Effect of protein/essential amino acids and resistance training on skeletal muscle hypertrophy: A case for whey protein. Nutr Metab, 17;7:51.
  • Referans28 Ikeda M., Sugiyama K., Tanaka T., Tanaka K., Sekihara H., Shimotohno K. (1998). Lactoferrin markedly inhibits hepatitis C virus infection in cultured human hepatocytes. Biochem. Biophys. Res. Commun, 245,549553.
  • Referans29 Jelen P. (2009). Whey-based functional beverages. In: Paquin, P. (ed.) Functional and speciality beverage technology. CRC Press, p. 259-296.
  • Referans30 Jelicic I., Botanic R., Tratnik R. (2008). Whey based beverages-new generation of dairy products. Mljekarstvo, 58: 257-274
  • Referans31 Jooyandeh H. (2009). Effect of fermented whey protein concentrate on texture of Iranian white cheese. Journal of Texture Studies, 40:497-510.
  • Referans32 Kassem J.M. (2015). Future challenges of whey proteins. Int. J. Dairy Sci, 10 (4), 139-159.
  • Referans33 Khalifa I., Peng J., Jia Y., Li J., Zhu W., Yu-Juan X. (2019). Anti-glycation and anti-hardening effects of microencapsulated mulberry polyphenols in high-protein- sugar ball models through binding with some glycation sites of whey proteins.International Journal of Biological Macromolecules, 123, 10–19.
  • Referans34 Kim D.H., Chun S.H., Oh N., Lee J.Y., Lee K.W. (2019). Anti-inflammatory activities of Maillard reaction products from whey protein isolate fermented by Lactobacillus gasseri 4M13 in lipopolysaccharide-stimulated RAW264.7 cells. Journal of Dairy Science, 102, (9), 7707-7716.
  • Referans35 Kimball S.R., Jefferson L.S.(2006). Signaling pathways and molecular mechanisms through which branched-chain amino acids mediate translational control of protein synthesis. J Nutr, 136(1 Suppl):227S-31S.
  • Referans36 Layman D.K., Lönnerdal B., Fernstrom J.D. (2018). Applications for α-lactalbumin in human nutrition. Nutr Rev, 1;76(6):444-460.
  • Referans37 Liberman K., Njemini R., Luiking Y., Forti L.N., Verlaan S., Bauer J.M. (2019). Thirteen weeks of supplementation of vitamin D and leucine-enriched whey protein nutritional supplement attenuates chronic low-grade inflammation in sarcopenic older adults: The provide study. Aging Clinical and Experimental Research, 31(6),845–854.
  • Referans38 Luhovyy B.L., Akhavan T., Anderson G.H.(2007). Whey proteins in the regulation of food intake and satiety. Journal of the American College of Nutrition, 26(6):704S-712S.
  • Referans39 Madadlou A., Abbaspourrad A. (2018). Bioactive whey peptide particles: An emerging class of nutraceutical carriers. Critical Reviews in Food Science and Nutrition, 58:(9), 1468–1477.
  • Referans40 Mangano K.M., Bao Y., Zhao C. (2019). Nutritional properties of whey proteins. Whey Protein Production, Chemistry, Functionality, and Applications, 103–140.
  • Referans41 Mann B., Kumari A., Kumar R., Sharma R., Prajapati K., Mahboob S. (2015). Antioxidant activity of whey protein hydrolysates in milk beverage system. Journal of Food Science and Technology, 52(6), 3235–3241.
  • Referans42 Marshall K. (2004). Therapeutic applications of whey protein. Altern. Med. Rev, 9,136-156.
  • Referans43 McClements J. (1995). Advances in the application of ultrasound in food analysis and processing. Trends Food Sci. Technol, 6, 293299.
  • Referans44 McIntosh G.H., Royle P.J., Le Leu R.K., Regester G.O., Johnson M.A., Grinsted R.L. (1998). Whey proteins as functional food ingredients. Int. Dairy J, 8, 425434.
  • Referans45 Micke P, Beeh KM, Buhl R (2002). Effects of longterm supplementation with whey proteins on plasma glutathione levels of HIV-infected patients. Eur J Nutr, 41(1):12-8.
  • Referans46 Miller P.E., Alexander D.D., Perez V. (2014). Effects of whey protein and resistance exercise on body composition: a meta-analysis of randomized controlled trials. J Am Coll Nutr, 33(2):163-75.
  • Referans47 Moreno Y.F., Sgarbieri V.C., Da Silva M.N., Toro A.A., Vilela M.M. (2006). Features of whey protein concentrate supplementation in children with rapidly progressive HIV infection, J. Trop. Pediatr. 52 (1):34-38.
  • Referans48 Morley J.E. (2007). Weight loss in older persons: new therapeutic approaches. Curr Pharm Des,13(35):3637-47.
  • Referans49 Mortensen L.S. (2012). Effects of different fractions of whey protein on postprandial lipid and hormone responses in type 2 diabetes. Eur J Clin Nutr, 66(7):799-805.
  • Referans50 Muro Urista C., Álvarez Fernández R., Riera Rodriguez F., Arana Cuenca A., Téllez Jurado A. (2011). Review: Production and functionality of active peptides from milk. Food Science and Technology International, 17(4), 293–317.
  • Referans51 Nabuco H.C.G., Tomeleri C.M., Fernandes R.R. (2019). Effects of pre- or post-exercise whey protein supplementation on oxidative stress and antioxidant enzymes in older women. Scand J Med Sci Sports, 29: 1101– 1108.
  • Referans52 Paddon-Jones D, Rasmussen B.B. (2009). Dietary protein recommendations and ththerapy. Curr Opin Clin Nutr Metab Care, 12(1):86-90.
  • Referans53 Pal S., Ellis V., Dhaliwal S. (2010). Effects of whey protein isolate on body composition, lipids, insulin and glucose in overweight and obese individuals. Br J Nutr, 104(5):716-23.
  • Referans54 Pal S., Ellis V. (2010). The chronic effects of whey proteins on blood pressure, vascular function, and inflammatory markers in overweight individuals. Obesity, 18, 13541359.
  • Referans55 Pal, S., Radavelli-Bagatini S. (2013). The effects of whey protein on cardiometabolic risk factors. Obesity Rev, 14: 324-343.
  • Referans56 Patel S. (2015). Emerging trends in nutraceutical applications of whey protein and its derivatives. J. Food Sci.Technol, 52 (11), 68476858.
  • Referans57 Perez-Cano F.J., Marın-Galle´n S., Castell M., Rodriguez-Palmero M., Rivero M., Franch A. (2007). Bovine whey protein concentrate supplementation modulates maturation of immune system in suckling rats. Br. J. Nutr, 98, S80S84.
  • Referans58 Philipina A. Marcelo H.R. (2008). Physicochemical properties of liquid virgin whey protein isolate. International Dairy Journal, 18:236-246.
  • Referans59 Pins J.J., Keenan J.M. (2002). Antihypertensive effects of a hydrolyzed whey protein isolate supplement (BioZate®1), Presented at the 11th International Congress on Cardiovascular Pharmacotherapy, Montreal, Quebec, Canada.
  • Referans60 Salehi A., Gunnerud U., Muhammed S.J. (2012). The insulinogenic effect of whey protein is partially mediated by a direct effect of amino acids and GIP on β-cells. NutrMetab , 9, 48.
  • Referans61 Shankar J.R., Bansal G.K., (2013). A study on health benefits of whey proteins. Int. J. Adv. Biotechnol. Res.,4 :15-19.
  • Referans62 Smithers G.W. (2008). Whey and whey proteins-From ‘gutter-to-gold’. International Dairy Journal., 18:695-704.
  • Referans63 Solak B.B., Akin N. (2012). Health benefits of whey protein: a review. J. Food Sci. Eng, 2, 129137.
  • Referans64 Sousa G.T.D., Lira F.S., Rosa J.C., Oliveira E.P., Oyama, L.M., Santos R.V. (2012). Dietary whey protein lessens several risk factors for metabolic diseases: a review. Lipids Health Dis, 11, 6775.
  • Referans65 Tang J.E., Moore D.R., Kuj S., Kellogg M.D., Maresh C.M., Kraemer W.J. (2013). Whey protein supplementation during resistance training augments lean body mass. J Am Coll Nutr, 32(2):122-35.
  • Referans66 Tomé D. (2009). Protein, amino acids, vagus nerve signaling, and the brain. The American Journal of Clinical Nutrition, 90(3): 838S-843S.
  • Referans67 Tripathi V., Jha Y.K. (2004). Development of Whey Beverage with Antagonistic Characteristics and Probiotics. International Journal of Food Properties, 7:2, 261-272.
  • Referans68 Tsai W.Y., Chang W.H., Chen C.H. (2000). Enchancing effect of patented whey protein isolate on cytotoxicity of an anticancer drug. Nutr. Cancer, 38:200-208.
  • Referans69 Tuomilehto J., Lindström J., Eriksson J.G. (2001). Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med, 344(18):1343-50.
  • Referans70 Van Loon L.J., Saris W.H., Verhagen H., Wagenmakers A.J. (2000). Plasma insulin responses after ingestion of different amino acid or protein mixtures with carbohydrate. Am. J. Clin. Nutr,721: 96-105.
  • Referans71 Wirunsawanya K., Upala S., Jaruvongvanich V., Sanguankeo A. (2018). Whey protein supplementation improves body composition and cardiovascular risk factors in overweight and obese patients: A systematic review and meta-analysis. J Am Coll Nutr, 37:60-70.
  • Referans72 Yamaguchi M., Yoshida K., Uchida M.(2009). Novel functions of bovine milk-derived alphalactalbumin: Anti-nociceptive and antiinflammatory activity caused by inhibiting cyclooxygenase-2 and phospholipase A2. Biol Pharm Bull,32(3):366-71.
  • Referans73 Zemel M.B. (2004). Role of calcium and dairy products in energy partitioning and weight management. Am J Clin Nutr,79(5):907S-12S.
There are 73 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Derlemeler
Authors

Esra Aktan 0000-0002-9673-7044

Asli Uçar 0000-0001-9724-9571

Publication Date December 25, 2022
Submission Date August 5, 2021
Acceptance Date March 25, 2022
Published in Issue Year 2022 Volume: 4 Issue: 3

Cite

APA Aktan, E., & Uçar, A. (2022). Peynir Altı Suyu Protein Takviyesi ve Sağlık Üzerindeki Potansiyel Etkileri. Genel Sağlık Bilimleri Dergisi, 4(3), 318-329.


                                                Journal of General Health Sciences is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY NC).