Clinical Research

Evaluation of Inflammatory Response with Complete Blood Count Parameters in Abdominal, Vaginal, and Laparoscopic Hysterectomy Techniques: A Retrospective Cohort Study

Volume: 22 Number: 3 September 30, 2025
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Evaluation of Inflammatory Response with Complete Blood Count Parameters in Abdominal, Vaginal, and Laparoscopic Hysterectomy Techniques: A Retrospective Cohort Study

Abstract

Aim: The aim of our study was to evaluate the inflammatory response in abdominal hysterectomy (AH), vaginal hysterectomy (VH), and laparoscopic hysterectomy (LH) techniques using complete blood count (CBC) parameters and to demonstrate the role of the delta neutrophil index (DNI) in hysterectomy types. Materials and Methods: The study included 251 patients. Patients were divided into three groups: AH, VH, and LH. Patient demographic characteristics, operational characteristics, and CBC results (white blood cell (WBC), neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and DNI) were compared separately for the three groups before surgery, at 6 hours postoperatively, and at 24 hours postoperatively. Results: The age and menopause rate of patients in the VH (n=84) group were higher than the LH (n=82) and AH (n=84) groups (P < 0.05). The operative time was longest in the LH group and shortest in the AH group (P < 0.05). The highest WBC, NLR, and PLR levels at postoperative 6th hour were in the AH group, and the lowest levels were in the VH group (P < 0.01). There were no significant differences in serum DNI levels between the LH, AH, and VH groups preoperatively and at the 6th and 24th hours postoperatively. Conclusion: We found the highest postoperative inflammatory response in the AH group and the lowest in the VH group, and contrary to many studies, we found that LH patients had an average inflammatory response. Although DNI increased in the postoperative inflammatory process, there was no difference between the AH, LH, and VH groups.

Keywords

References

  1. 1 Özsürmeli M, Türkay Ü, Salıcı B, Salıcı M, Bölge KN, Terzi H. Evaluation of inflammatuar response in hysterectomies: a retrospective study in Kocaeli, Turkey. Ginekol Pol 2021;92(2):105-109. 2 Blears EE, Pham NK, Bauer VP. A systematic review and meta-analysis of valued obstetric and gynecologic (OB/ GYN) procedures in resource-poor areas. Surg Open Sci 2020;12;2(3):127-135.

Details

Primary Language

English

Subjects

Health Services and Systems (Other)

Journal Section

Clinical Research

Publication Date

September 30, 2025

Submission Date

August 4, 2025

Acceptance Date

August 24, 2025

Published in Issue

Year 2025 Volume: 22 Number: 3

APA
Halilzade, İ., Halilzade, M. İ., & Taş, E. (2025). Evaluation of Inflammatory Response with Complete Blood Count Parameters in Abdominal, Vaginal, and Laparoscopic Hysterectomy Techniques: A Retrospective Cohort Study. Jinekoloji-Obstetrik Ve Neonatoloji Tıp Dergisi, 22(3), 367-372. https://doi.org/10.38136/jgon.1758337
AMA
1.Halilzade İ, Halilzade Mİ, Taş E. Evaluation of Inflammatory Response with Complete Blood Count Parameters in Abdominal, Vaginal, and Laparoscopic Hysterectomy Techniques: A Retrospective Cohort Study. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi. 2025;22(3):367-372. doi:10.38136/jgon.1758337
Chicago
Halilzade, İnci, Mohammad İbrahim Halilzade, and Erdem Taş. 2025. “Evaluation of Inflammatory Response With Complete Blood Count Parameters in Abdominal, Vaginal, and Laparoscopic Hysterectomy Techniques: A Retrospective Cohort Study”. Jinekoloji-Obstetrik Ve Neonatoloji Tıp Dergisi 22 (3): 367-72. https://doi.org/10.38136/jgon.1758337.
EndNote
Halilzade İ, Halilzade Mİ, Taş E (September 1, 2025) Evaluation of Inflammatory Response with Complete Blood Count Parameters in Abdominal, Vaginal, and Laparoscopic Hysterectomy Techniques: A Retrospective Cohort Study. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 22 3 367–372.
IEEE
[1]İ. Halilzade, M. İ. Halilzade, and E. Taş, “Evaluation of Inflammatory Response with Complete Blood Count Parameters in Abdominal, Vaginal, and Laparoscopic Hysterectomy Techniques: A Retrospective Cohort Study”, Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi, vol. 22, no. 3, pp. 367–372, Sept. 2025, doi: 10.38136/jgon.1758337.
ISNAD
Halilzade, İnci - Halilzade, Mohammad İbrahim - Taş, Erdem. “Evaluation of Inflammatory Response With Complete Blood Count Parameters in Abdominal, Vaginal, and Laparoscopic Hysterectomy Techniques: A Retrospective Cohort Study”. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 22/3 (September 1, 2025): 367-372. https://doi.org/10.38136/jgon.1758337.
JAMA
1.Halilzade İ, Halilzade Mİ, Taş E. Evaluation of Inflammatory Response with Complete Blood Count Parameters in Abdominal, Vaginal, and Laparoscopic Hysterectomy Techniques: A Retrospective Cohort Study. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi. 2025;22:367–372.
MLA
Halilzade, İnci, et al. “Evaluation of Inflammatory Response With Complete Blood Count Parameters in Abdominal, Vaginal, and Laparoscopic Hysterectomy Techniques: A Retrospective Cohort Study”. Jinekoloji-Obstetrik Ve Neonatoloji Tıp Dergisi, vol. 22, no. 3, Sept. 2025, pp. 367-72, doi:10.38136/jgon.1758337.
Vancouver
1.İnci Halilzade, Mohammad İbrahim Halilzade, Erdem Taş. Evaluation of Inflammatory Response with Complete Blood Count Parameters in Abdominal, Vaginal, and Laparoscopic Hysterectomy Techniques: A Retrospective Cohort Study. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi. 2025 Sep. 1;22(3):367-72. doi:10.38136/jgon.1758337