Investigating In Vitro Antioxidant and Antimicrobial Activity of Different Sorbus Species in Artvin Province of Türkiye

Abstract

In the present study, three Sorbus species in the Rosaceae family naturally growing in Artvin province of Turkey were collected. To determine the antioxidant activity, total phenolic and flavonoids capacity of the extracts, their scavenging capacity for (2,2-diphenyl-1-picrylhydrazyl (DPPH) radical, reducing capacity for Fe3+ (FRAP) and copper (II) ions (CUPRAC) were analyzed. Besides, disc diffusion method was used to determine antibacterial activity. It was found that all Sorbus fruit, flower, leaf and pedicle methanolic extracts showed different levels of antioxidant activity. Results of the the total polyphenol, total flavonoid, FRAP, CUPRAC and DPPH analysis, the highest activity was measured in S. persica pedicle, S. umbellate var. cretica leaf, S. persica leaf, S. umbellata var. cretica leaf and S. persica leaf extracts as 25.7 ± 16.49 mg GAE/g, 7.469 ± 0.4926 mg of quercetin/g, 6.248 ± 0.2374 μmol FeSO4.7H2O/g and, 164.4 ± 4.209 mmol TEAC and 46.33 μg/mL, respectively. It was revealed that methanolic extracts of Sorbus plant showing antibacterial activity had very high minimum inhibitory concentration (MIC) values compared to ampicillin. Thus, considering the findings of the present study, it could be stated that these species merit further studies as natural antioxidant and antibacterial sources.

Keywords

• Antimicrobial
• Antioxidant
• Methanolic
• extraction
• Sorbus

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