Comparison of Antioxidant Activities of Mono-, Di- and Tri-substituted Coumarins

Abstract

In this study; Numerous coumarin compounds were synthesized by Pechmann and Knoevenagel methods, and the substitution of the formyl group was provided by the Duff reaction. The IR spectras and melting points of the synthesized compounds were compared with the literature values. Also confirmed by GC/MS analysis. And the synthesized coumarin derivatives were compared in terms of antioxidant activity according to DPPH and Cuprac methods. The main aim of the study is to determine the effects of substituents on antioxidant activity.

Keywords

• Coumarin,Pechmann reaction,Knoevenagel reaction,Duff reaction,Cuprac method,DDPH method

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