Antarktik Mikroalg Ekstrelerinin Antioksidan Potansiyeli, Fenolik İçeriği ve Antimikrobiyal Etkileri

Anıl Tevfik Koçer; Benan İnan; Meyrem Vehapi; Gülcan Ayşin Karaca; Beyza Karacaoğlu; Didem Balkanlı

Antarktik Mikroalg Ekstrelerinin Antioksidan Potansiyeli, Fenolik İçeriği ve Antimikrobiyal Etkileri

Abstract

Amaç: Son yıllarda, kontrolsüz ilaç tüketimi nedeniyle artan patojen mikroorganizmaların antimikrobiyal ajanlara karşı direnç göstermesi önemli bir sorun haline gelmiştir. Bu bağlamda yapılan çalışmalarda, mikroalglerin bu sorunun çözümü için büyük bir potansiyele sahip bir seçenek olduğu görülmüştür. Özellikle ekstrem koşullarda büyüyebilen mikroalglerin, içerdiği farklı biyoaktif bileşenler sayesinde antimikrobiyal özelliklerinin yanı sıra antikanser, antioksidan ve anti-inflamatuar özellikler gösterebildiği belirlenmiştir. Bu çalışmada, Antarktika’nın Horseshoe Adası, Skua Gölü’nden izole edilen Chlorella variabilis YTU.ANTARCTIC.001 türü üzerine odaklanılmış ve bu türün antimikrobiyal potansiyeli ilk kez kapsamlı olarak değerlendirilmiştir. Gereç ve Yöntem: Çalışmada, farklı çözücüler (etanol, metanol, DMSO ve su) kullanılarak hazırlanan ekstrelerin hem antibakteriyel hem de antifungal etkileri sistematik olarak analiz edilmiştir. Bulgular: Bu çalışmanın sonuçları, Antarktik mikroalg ekstrelerinin Bacillus cereus ve Botrytis cinerea’ya karşı en yüksek antibakteriyel ve antifungal aktiviteyi gösterdiğini ortaya koymuştur. Sonuç: Çalışmanın sonucunda, elde edilen ekstrelerin kozmetik ve farmasötik gibi endüstrilerde antimikrobiyal ajanlar olarak kullanılabileceği sonucuna ulaşılmıştır.

Keywords

References

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Details

Primary Language

Turkish

Subjects

Pharmacology and Pharmaceutical Sciences (Other)

Journal Section

Research Article

Authors

Anıl Tevfik Koçer ^*
0000-0003-1519-1711
Türkiye

Benan İnan
0000-0002-2315-3099
Türkiye

Meyrem Vehapi
0000-0001-8235-3552
Türkiye

Gülcan Ayşin Karaca This is me
0000-0003-3905-851X
Türkiye

Beyza Karacaoğlu
0000-0001-7666-1911
Türkiye

Didem Balkanlı
0000-0003-2483-7617
Türkiye

Publication Date

May 29, 2025

Submission Date

March 5, 2025

Acceptance Date

April 16, 2025

Published in Issue

Year 2025 Volume: 1 Number: 1

IZ

https://izlik.org/JA72WS56RY

Cite

RIS / Bibtex

APA

Koçer, A. T., İnan, B., Vehapi, M., Karaca, G. A., Karacaoğlu, B., & Balkanlı, D. (2025). Antarktik Mikroalg Ekstrelerinin Antioksidan Potansiyeli, Fenolik İçeriği ve Antimikrobiyal Etkileri. IYYU Journal of PhytoPharmacy, 1(1), 9-20. https://izlik.org/JA72WS56RY

AMA

1.Koçer AT, İnan B, Vehapi M, Karaca GA, Karacaoğlu B, Balkanlı D. Antarktik Mikroalg Ekstrelerinin Antioksidan Potansiyeli, Fenolik İçeriği ve Antimikrobiyal Etkileri. JPP. 2025;1(1):9-20. https://izlik.org/JA72WS56RY

Chicago

Koçer, Anıl Tevfik, Benan İnan, Meyrem Vehapi, Gülcan Ayşin Karaca, Beyza Karacaoğlu, and Didem Balkanlı. 2025. “Antarktik Mikroalg Ekstrelerinin Antioksidan Potansiyeli, Fenolik İçeriği Ve Antimikrobiyal Etkileri”. IYYU Journal of PhytoPharmacy 1 (1): 9-20. https://izlik.org/JA72WS56RY.

EndNote

Koçer AT, İnan B, Vehapi M, Karaca GA, Karacaoğlu B, Balkanlı D (May 1, 2025) Antarktik Mikroalg Ekstrelerinin Antioksidan Potansiyeli, Fenolik İçeriği ve Antimikrobiyal Etkileri. IYYU Journal of PhytoPharmacy 1 1 9–20.

IEEE

[1]A. T. Koçer, B. İnan, M. Vehapi, G. A. Karaca, B. Karacaoğlu, and D. Balkanlı, “Antarktik Mikroalg Ekstrelerinin Antioksidan Potansiyeli, Fenolik İçeriği ve Antimikrobiyal Etkileri”, JPP, vol. 1, no. 1, pp. 9–20, May 2025, [Online]. Available: https://izlik.org/JA72WS56RY

ISNAD

Koçer, Anıl Tevfik - İnan, Benan - Vehapi, Meyrem - Karaca, Gülcan Ayşin - Karacaoğlu, Beyza - Balkanlı, Didem. “Antarktik Mikroalg Ekstrelerinin Antioksidan Potansiyeli, Fenolik İçeriği Ve Antimikrobiyal Etkileri”. IYYU Journal of PhytoPharmacy 1/1 (May 1, 2025): 9-20. https://izlik.org/JA72WS56RY.

JAMA

1.Koçer AT, İnan B, Vehapi M, Karaca GA, Karacaoğlu B, Balkanlı D. Antarktik Mikroalg Ekstrelerinin Antioksidan Potansiyeli, Fenolik İçeriği ve Antimikrobiyal Etkileri. JPP. 2025;1:9–20.

MLA

Koçer, Anıl Tevfik, et al. “Antarktik Mikroalg Ekstrelerinin Antioksidan Potansiyeli, Fenolik İçeriği Ve Antimikrobiyal Etkileri”. IYYU Journal of PhytoPharmacy, vol. 1, no. 1, May 2025, pp. 9-20, https://izlik.org/JA72WS56RY.

Vancouver

1.Anıl Tevfik Koçer, Benan İnan, Meyrem Vehapi, Gülcan Ayşin Karaca, Beyza Karacaoğlu, Didem Balkanlı. Antarktik Mikroalg Ekstrelerinin Antioksidan Potansiyeli, Fenolik İçeriği ve Antimikrobiyal Etkileri. JPP [Internet]. 2025 May 1;1(1):9-20. Available from: https://izlik.org/JA72WS56RY