The Role of Vitamins in Alzheimer's Disease

Year 2022, , 1 - 18, 29.04.2022

Seçil Müderrisoğlu , Gül Yarım

https://doi.org/10.47115/jshs.977442

Abstract

Alzheimer's disease is a progressive neurodegenerative disease that occurs due to loss of neurons and synapses in various parts of the central nervous system, characterized by decreased cognitive functions, self-care deficits, and various neuropsychiatric and behavioral disorders. Many factors such as oxidative stress, abnormal tau protein, amyloid deposition, metabolism, inflammation, age, genetic factors, head trauma, vascular damage, infections, environmental factors and nutrition play a role in the etiology of Alzheimer's disease, which is a multifactorial disease. Prophylactic and therapeutic approaches are being developed against Alzheimer's disease, which has a significant impact on human life and has not yet been fully cured. Emphasizing the importance of healthy nutrition in Alzheimer's disease, patients and their relatives are tried to be informed. In this review, information about the role and importance of vitamins associated with Alzheimer's disease, which has become an important health problem for the whole world, is presented.

Keywords

Alzheimer’s Disease, Nutrition, Vitamin

ALZHEİMER HASTALIĞINDA VİTAMİNLERİN ROLÜ

Abstract

Alzheimer hastalığı, merkezi sinir sisteminin çeşitli bölgelerinde nöron ve sinaps kayıpları nedeniyle ortaya çıkan, bilişsel işlevlerde azalma, öz bakım eksiklikleri, çeşitli nöropsikiyatrik ve davranışsal bozukluklar ile karakterize progresif bir nörodejeneratif hastalıktır. Çok faktörlü bir hastalık olan Alzheimer hastalığının etiyolojisinde oksidatif stres, anormal tau protein metabolizması, amiloid birikimi, enflamasyon, yaş, genetik faktörler, kafa travmaları, vasküler hasar, enfeksiyonlar, çevresel faktörler ve beslenme gibi birçok faktör rol oynamaktadır. İnsan hayatını önemli ölçüde etkileyen, henüz tam olarak tedavi edilemeyen Alzheimer hastalığına karşı profilaktik ve tedavi edici yaklaşımlar geliştirilmektedir. Alzheimer hastalığında sağlıklı beslenmenin önemi vurgulanarak hastalar ve yakınları bilgilendirilmeye çalışılmaktadır. Bu derlemede, tüm dünya için önemli bir sağlık sorunu haline gelen Alzheimer hastalığı ile ilişkili vitaminlerin hastalıktaki rolü ve önemi hakkında bilgiler sunulmuştur.

Keywords

Alzheimer hastalığı, beslenme, vitamin

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