Case Report

Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management

Volume: 16 Number: 2 August 6, 2026
EN

Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management

Abstract

This case report presents the medical management of a 34-year-old patient diagnosed with an early-stage tubal ectopic pregnancy characterized by menstrual delay, mild pelvic pain, and elevated C-reactive protein (CRP) levels in laboratory findings, but no signs of rupture. The potential causes of elevated CRP, even in unruptured ectopic pregnancies, and its relationship to treatment approaches are discussed.

Keywords

References

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  2. 2. Baggio S, Garzon S, Russo A, Ianniciello CQ, Santi L, Laganà AS, et al. Fertility and reproductive outcome after tubal ectopic pregnancy: comparison among methotrexate, surgery and expectant management. Arch Gynecol Obstet. 2021;303:259–268. https://doi.org/10.1007/s00404-020-05749-2
  3. 3. RG, TD. 3-year analysis of prognostic factors affecting success in single-dose methotrexate treatment: A single-center experience. Perinatol J. 2018;26:2–3. https://doi.org/10.2399/ prn.18.0262006
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  5. 5. Cohen Y, Ascher-Landsberg J, Cohen A, Lessing JB, Grisaru D. The role of C-reactive protein measurement as a diagnostic aid in early pregnancy. Eur J Obstet Gynecol Reprod Biol. 2014;176:64–67. https://doi.org/10.1016/j.ejogrb.2014.03.004
  6. 6. Theron GB, Shepherd EG, Strachan AF. C-reactive protein levels in ectopic pregnancy, pelvic infection and carcinoma of the cervix. S Afr Med J. 1986;24:681–682.
  7. 7. Drugs and Lactation Database (LactMed®). Bethesda (MD): National Institute of Child Health and Human Development;Methotrexate. https://www.ncbi.nlm.nih.gov/books/ NBK501341/
  8. 8. Sacks GP, Seyani L, Lavery S, Trew G. Maternal C-reactive protein levels are raised at 4 weeks gestation. Hum Reprod. 2004;19:1025–1030. https://doi.org/10.1093/humrep/ deh179

Details

Primary Language

English

Subjects

Clinical Sciences (Other)

Journal Section

Case Report

Publication Date

August 6, 2026

Submission Date

July 16, 2025

Acceptance Date

February 10, 2026

Published in Issue

Year 2026 Volume: 16 Number: 2

APA
Türker Aras, Ü. A., Dutoğlu, E., & Dinçgez, B. (2026). Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management. Kafkas Journal of Medical Sciences, 16(2), 250-252. https://izlik.org/JA57XS84ML
AMA
1.Türker Aras ÜA, Dutoğlu E, Dinçgez B. Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management. Kafkas Journal of Medical Sciences. 2026;16(2):250-252. https://izlik.org/JA57XS84ML
Chicago
Türker Aras, Ülkü Ayşe, Ezgi Dutoğlu, and Burcu Dinçgez. 2026. “Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management”. Kafkas Journal of Medical Sciences 16 (2): 250-52. https://izlik.org/JA57XS84ML.
EndNote
Türker Aras ÜA, Dutoğlu E, Dinçgez B (August 1, 2026) Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management. Kafkas Journal of Medical Sciences 16 2 250–252.
IEEE
[1]Ü. A. Türker Aras, E. Dutoğlu, and B. Dinçgez, “Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management”, Kafkas Journal of Medical Sciences, vol. 16, no. 2, pp. 250–252, Aug. 2026, [Online]. Available: https://izlik.org/JA57XS84ML
ISNAD
Türker Aras, Ülkü Ayşe - Dutoğlu, Ezgi - Dinçgez, Burcu. “Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management”. Kafkas Journal of Medical Sciences 16/2 (August 1, 2026): 250-252. https://izlik.org/JA57XS84ML.
JAMA
1.Türker Aras ÜA, Dutoğlu E, Dinçgez B. Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management. Kafkas Journal of Medical Sciences. 2026;16:250–252.
MLA
Türker Aras, Ülkü Ayşe, et al. “Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management”. Kafkas Journal of Medical Sciences, vol. 16, no. 2, Aug. 2026, pp. 250-2, https://izlik.org/JA57XS84ML.
Vancouver
1.Ülkü Ayşe Türker Aras, Ezgi Dutoğlu, Burcu Dinçgez. Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management. Kafkas Journal of Medical Sciences [Internet]. 2026 Aug. 1;16(2):250-2. Available from: https://izlik.org/JA57XS84ML